Solitary Flat Bone Metastasis of Follicular Thyroid Carcinoma: Complete Molecular and Partial Structural Response After 2 131 I Therapies.
Rangat Bagasariya, Priyanka Verma, Sandip Basu
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Case in brief
A patient with follicular thyroid carcinoma presented with a solitary metastasis in the right iliac bone, which remained structurally unchanged after two high-dose 131 I therapies. Despite the persistence of the lesion, it exhibited no uptake on various imaging modalities, indicating a lack of metabolic activity. This case underscores the importance of molecular imaging in evaluating treatment response.
What made this case unusual
The lesion's structural persistence contrasted with its lack of metabolic activity on multiple imaging techniques, highlighting a significant discordance.
Diagnostic / clinical pearl
Clinicians should consider the role of molecular imaging in assessing treatment response, particularly when structural lesions remain unchanged.
Why it matters
This case emphasizes the need for integrating molecular imaging into the evaluation of differentiated thyroid carcinoma to better inform management decisions.