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Outcomes with Catheter-Directed Thrombolysis versus Mechanical Thrombectomy for Patients with Intermediate/High Risk Pulmonary Embolism: A Meta-Analysis of 24,090 Patients.

LungNov 10, 2026Open access

This meta-analysis compared catheter-directed thrombolysis (CDT) with mechanical thrombectomy (MT) in patients with intermediate- or high-risk pulmonary embolism treated with catheter-based therapies.

Why it matters

For intermediate- or high-risk pulmonary embolism managed with catheter-based treatment, this synthesis found no clear difference between CDT and MT in mortality, major bleeding, or several other clinical outcomes.

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