Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportRheumatology

Rheumatoid factor positivity in ANCA-negative eosinophilic granulomatosis with polyangiitis: cardiac mimicry, mononeuritis multiplex, and long-term outcome in a case-based systematic review.

Rheumatol IntNov 10, 2026Open access

A 42-year-old woman with long-standing asthma and rheumatoid factor (RF) of 322 IU/mL presented with myocardial infarction-like cardiac involvement despite non-obstructive coronary arteries.

Clinical pearl

High RF positivity does not exclude EGPA. In a patient with asthma, eosinophilia, and compatible ENT, neurologic, or cardiac manifestations, consider EGPA even when ANCA is negative and RF is elevated.

Read case

Also worth knowing

Case ReportRheumatology

Bone marrow sarcoidosis in Takayasu arteritis: Case report and literature review.

A 46-year-old woman with confirmed Takayasu arteritis presented with elevated systemic inflammatory markers and diffuse hypermetabolic activity on PET.

Medicine (Baltimore)Nov 6, 2026Read case
Case ReportRheumatologyOpen access

Pulmonary-Cardiac Involvement in a Patient with IgA Vasculitis.

A 41-year-old woman with biopsy-proven IgA nephropathy presented with progressive dyspnea, hemoptysis, and a painful purpuric rash.

Methodist Debakey Cardiovasc JNov 3, 2026Read case
Case ReportPediatrics

Paraneoplastic Autoimmune Multiorgan Syndrome: Diagnostic Lessons for Pediatricians.

An 11-year-old boy developed subacute erythroblastopenia, followed by polymorphic mucocutaneous findings, severe myositis with a dermatomyositis-like phenotype, and mild hepatitis.

PediatricsNov 1, 2026Read case
Case ReportRheumatologyOpen access

Severe ARDS and secondary haemophagocytic lymphohistiocytosis complicating a flare of adult-onset Still's disease: a case-based review.

A 42-year-old woman with adult-onset Still’s disease (AOSD) developed a flare after a five-week interruption of conventional synthetic disease-modifying therapy around surgery for a perianal abscess with fistulous…

Rheumatol IntOct 31, 2026Read case
Case ReportNephrology

Voclosporin for the treatment of lupus nephritis flares in patients with inadequate response to mycophenolate mofetil and belimumab: a case series.

This case series describes three patients with lupus nephritis (LN) flares and nephrotic-range proteinuria despite treatment with mycophenolate mofetil and belimumab.

J NephrolOct 30, 2026Read case
Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.