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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportPlastic Surgery

Optimizing survival and long-term outcomes in complex pediatric digital amputations: a case report with a 6.5-year follow-up.

J Plast Surg Hand SurgNov 11, 2026

A 1.5-year-old boy sustained complete thermal-crush amputations of the left index, middle, and ring fingers in an industrial sealer injury.

Clinical pearl

In this case, a targeted replantation strategy preserved digit length while achieving survival and favorable long-term function and growth after complex pediatric thermal-crush injury.

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Also worth knowing

Case ReportOrthopedic Surgery

Simultaneous Infection Control and Reconstruction Using Continuous Local Antibiotic Perfusion in Septic Knee With Extensive Soft Tissue Defect: A Case Report.

A 69-year-old woman presented 2.5 months after patellar fracture fixation with methicillin-resistant Staphylococcus aureus infection, septic knee arthritis, and a 12×8 cm anterior soft tissue defect with joint exposure.

Am J Case RepNov 9, 2026Read case
Case ReportPlastic Surgery

Reconstruction of the Burned Nose Using an Expanded Skin-Grafted Forehead Flap, Delayed Turnover Flaps, and Indocyanine Green Perfusion Assessment.

A 35-year-old man developed severe nasal deformity and airway compromise after a flame burn involving about 20% of total body surface area.

J Burn Care ResNov 4, 2026Read case
Case ReportPlastic SurgeryOpen access

Topical MSC-Derived Extracellular Vesicles Accelerate Healing of Second-Degree Burns: A Case Report.

A 48-year-old man with deep second-degree burns received a single topical dose of allogeneic bone marrow mesenchymal stem cell-derived extracellular vesicles within 48 hours of injury in an open-label phase 1/2a study.

J Burn Care ResNov 4, 2026Read case
Case ReportPlastic Surgery

Fascial Patch Reconstruction of a Gastric Conduit Defect Using an Anterolateral Thigh-Vastus Lateralis Composite Free Flap: A Case Report.

A 71-year-old man with a retrosternal gastric conduit developed a full-thickness rupture during coronary artery bypass grafting through median sternotomy.

MicrosurgeryNov 2, 2026Read case
Case ReportPlastic SurgeryOpen access

Conservative Management of Presumptive Free Flap Pedicle Compromise on Postoperative Day 6: Report of Two Cases and Literature Review.

Two patients underwent lower-extremity free-flap reconstruction for exposed tibial bone or hardware. On postoperative day 6, both developed loss of Doppler signal and clinical ischemia, raising concern for late pedicle…

MicrosurgeryNov 2, 2026Read case
Case ReportVascular Surgery

Orthoplastic Limb Salvage Using Transtibial Transport and Free-Flap Reconstruction in Patients With Diabetes-Related Chronic Limb-Threatening Ischemia.

A 56-year-old man with poorly controlled diabetes and severe peripheral arterial disease developed a chronic foot ulcer with toe gangrene despite unsuccessful revascularization, leaving no conventional revascularization…

J Am Acad Orthop Surg Glob Res RevNov 2, 2026Read case
Case ReportPlastic Surgery

From Shrapnel to Stability: A Reverse Perforator Flap for Definitive Elbow Coverage Seven Decades Post-Trauma. A Case Report.

A man injured by shrapnel at age four sustained a severe right elbow fracture and complete ulnar nerve transection, leaving ankylosis and chronic dysfunction.

Mil MedNov 1, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Diagnosis and Surgical Management of a Solitary Fibrofatty Lesion of the Finger Mimicking Pachydermodactyly.

A 30-year-old man had progressive, painless enlargement around the proximal interphalangeal joint of his right middle finger after long-term repetitive mechanical stimulation.

J Vis ExpOct 30, 2026Read case
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