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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

FeaturedClinical ResearchPediatrics

Gastric Residual Volume Assessment in Critically Ill Children: The GASTRIC-PICU Randomized Clinical Trial.

JAMASep 8, 2026Open access

The GASTRIC-PICU trial evaluated the impact of routine gastric residual volume (GRV) assessment on enteral feeding in critically ill children.

Why it matters

This study challenges the routine practice of GRV assessment in critically ill children, suggesting that it may not be necessary and could hinder nutritional delivery.

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Also worth knowing

Clinical ResearchPediatrics

Intimate Partner Violence Against Women and Mortality Among Children Younger Than 5 Years: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the association between intimate partner violence (IPV) against women and mortality among children under 5 years.

JAMA Netw OpenSep 1, 2026Open accessRead summary
Clinical ResearchNeurology

Improving survival in Duchenne muscular dystrophy across eras: a systematic review and cumulative meta-analysis.

This systematic review and cumulative meta-analysis evaluated survival trends in Duchenne muscular dystrophy (DMD) across eras, analyzing over 13,000 patients.

J NeurolSep 6, 2026Open accessRead summary
Clinical ResearchNephrology

Outcomes and learning curve of single-kidney transplantation from small pediatric donors in children: a retrospective cohort study with meta-analysis.

This retrospective cohort study evaluated outcomes of single-kidney transplantation from small pediatric donors in 77 children.

Pediatr Surg IntSep 6, 2026Open accessRead summary
Clinical ResearchPsychiatry

A multicenter randomized controlled effectiveness trial of transdiagnostic treatment for adolescents with subthreshold anxiety and depressive symptoms.

This multicenter randomized controlled trial evaluated the effectiveness of the Unified Protocol for Adolescents (UP-A) compared to progressive relaxation in 676 adolescents with subthreshold anxiety and depressive…

Psychol MedSep 4, 2026Read summary
Clinical ResearchMedical Genetics

Safety and efficacy of guanabenz in early-childhood onset vanishing white matter: primary analysis of a single-arm, phase 1/2 trial.

This single-arm, phase 1/2 trial evaluated the safety and efficacy of guanabenz in 31 children with early-childhood onset vanishing white matter.

Lancet NeurolSep 1, 2026Read summary
Clinical ResearchPediatrics

Triggering modalities to synchronise non-invasive respiratory support in preterm infants: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of synchronised nasal intermittent positive pressure ventilation (sNIPPV) in preterm infants, comparing it to other non-invasive respiratory support…

BMJ Paediatr OpenSep 8, 2026Read summary
Clinical ResearchPediatrics

Multisensory stimulation for promoting development and preventing morbidity in preterm infants.

This systematic review and meta-analysis evaluated the effects of multisensory stimulation on neurodevelopmental outcomes in preterm infants, comparing it to standard care and single-sensory interventions.

Cochrane Database Syst RevSep 3, 2026Open accessRead summary
Clinical ResearchObstetrics & Gynecology

Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.

This systematic review and meta-analysis evaluated the effectiveness of magnesium sulphate for fetal neuroprotection in women at risk of preterm birth.

Cochrane Database Syst RevSep 3, 2026Open accessRead summary
Clinical ResearchOncology (Medical)

EuroNet-PHL-LP1: complete resection or low-dose chemotherapy for pediatric low-risk nodular lymphocyte-predominant Hodgkin lymphoma.

The EuroNet-PHL-LP1 trial evaluated treatment strategies for pediatric patients with early-stage nodular lymphocyte-predominant Hodgkin lymphoma (nLPHL).

Blood AdvSep 6, 2026Open accessRead summary
Clinical ResearchPediatrics

Immunogenicity of Two Versus Three Doses of Hepatitis B Vaccine When Administered to Children Aged 2-18 Months: A Randomized Clinical Trial.

This randomized clinical trial evaluated the immunogenicity of 2-dose versus 3-dose hepatitis B vaccination schedules in children aged 2-18 months.

J Infect DisSep 2, 2026Open accessRead summary
Clinical ResearchInfectious Diseases

Predictors of Treatment Failure in Children With HIV Starting First-line Antiretroviral Therapy in the ODYSSEY Trial.

The ODYSSEY trial investigated predictors of treatment failure in 381 children starting first-line antiretroviral therapy (ART), primarily in Africa.

Clin Infect DisSep 2, 2026Open accessRead summary

Showing 12 of 42 publications that cleared our clinical screen in the last 14 days.

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