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Diagnostic yield and early outcomes of radical prostatectomy without prior histopathologic diagnosis: a single-arm systematic review and meta-analysis.
World J UrolNov 10, 2026Open access
This single-arm systematic review and random-effects meta-analysis assessed radical prostatectomy without prior histopathologic confirmation in adult men with high clinical suspicion of clinically significant prostate…
Why it matters
The findings suggest that imaging and clinical risk assessment can identify a group in whom prostatectomy without prior biopsy often yields clinically significant cancer, with few benign surgical specimens.