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186 articles
November 202618
The unseen risk: a systematic review of the incidence, management, and outcomes of the trigeminocardiac reflex in skull-base surgery.
This PRISMA-guided systematic review synthesized reports of intraoperative trigeminocardiac reflex (TCR) during skull-base and adjacent neurosurgical procedures.
Conservative versus surgical management of traumatic acute subdural hematoma: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared surgical with conservative management of traumatic acute subdural hematoma in adults.
Efficacy and safety of middle meningeal artery embolisation for chronic subdural haematoma: a systematic review and meta-analysis of randomised controlled trials.
This PRISMA-compliant systematic review and meta-analysis pooled randomised controlled trials comparing middle meningeal artery embolisation (MMAE)-based treatment with standard management in adults with radiologically…
Perioperative neurocognitive outcomes after robot-assisted pelvic surgery: a systematic review and meta-analysis of reported proportions, comparative risk and prognostic factors.
This systematic review and meta-analysis examined delirium and cognitive decline after robot-assisted pelvic surgery in adults, including reported proportions, comparative risk, and prognostic factors.
Surgical outcomes and functional morbidity after retrosigmoid/retrocondylar and midline suboccipital approaches for foramen magnum meningiomas: a single-arm meta-analysis.
This PRISMA-guided systematic review and single-arm meta-analysis assessed surgical control and functional morbidity after posterior or posterolateral approaches for foramen magnum meningiomas.
Paraspinal Muscle Quality and Functional Outcomes Following Lumbar Fusion: A Systematic Review.
This systematic review examined whether preoperative and postoperative paraspinal muscle quality is associated with patient-reported outcomes after lumbar interbody fusion, and whether findings differ between minimally…
Subsequent epilepsy surgery after SEEG-guided radiofrequency thermocoagulation: Outcomes and prognostic value of treatment response-a systematic review and meta-analysis.
This systematic review and meta-analysis assessed outcomes after resective, disconnective, or ablative epilepsy surgery in patients previously treated with SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC), and…
Optimal duration of levetiracetam prophylaxis following supratentorial tumor resection: a multi-study analysis.
This systematic review and meta-analysis compared short-course (≤ 9 days) with extended-course (> 9 days) levetiracetam prophylaxis in seizure-naïve patients after supratentorial tumor resection.
Rescue treatment for medium vessel occlusion by intra-arterial tenecteplase: the RESCUE-TNK randomized clinical trial.
The RESCUE-TNK phase 2, multicentre randomised trial evaluated intra-arterial tenecteplase versus standard care in patients with acute ischaemic stroke caused by medium vessel occlusion.
Syringomyelia secondary to degenerative spinal canal stenosis: a systematic review.
This PRISMA 2020 systematic review synthesised patient-level reports of syringomyelia associated with degenerative spinal canal stenosis, predominantly cervical spondylosis.
Salovum® reduces mortality in isolated severe traumatic brain injury: a randomized phase II trial.
This prospective, double-blind, placebo-controlled phase II randomized trial tested Salovum® in adults with isolated severe traumatic brain injury receiving intracranial pressure monitoring and neurointensive care at a…
Immunothrombosis Biomarkers and Multi-Omics Profiles After Successful Recanalization in Patients Receiving Ischemic Postconditioning: An Exploratory Analysis of the INSPIRE Trial.
This exploratory secondary analysis of the randomized INSPIRE trial examined 60 patients with ischemic stroke after successful endovascular thrombectomy recanalization.
Benson relaxation technique for perioperative anxiety and depressive symptoms in patients undergoing brain tumor surgery: a clinical trial.
This randomized controlled trial evaluated supervised Benson relaxation technique (BRT) sessions for perioperative anxiety and depressive symptoms in patients undergoing brain tumor resection.
Stereotactic radiosurgery for bilateral trigeminal neuralgia: A systematic review and proposed framework for staged treatment.
This systematic review assessed stereotactic radiosurgery (SRS) for medically refractory bilateral trigeminal neuralgia (BTN) in adults.
Predictive Accuracy and Procedural Benefits of Software-Enhanced Flow-Diverter Planning: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed whether software simulations improve flow-diverter (FD) planning and procedural outcomes for intracranial aneurysms compared with physician planning.
Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed imaging methods for visualizing deep cerebral perforating arteries in human studies.
Germline Genetic Variants and Epilepsy Surgery Response: Individual Participant Pooled Analysis of 272 Patients.
This systematic review and individual-participant pooled analysis examined seizure outcomes after resection or laser ablation in 272 people with pathogenic or likely pathogenic germline epilepsy variants, excluding…
Proteomic and Metabolomic Profiling in Moyamoya Disease: A Systematic Review.
This systematic review examined human studies using high-throughput proteomic or metabolomic methods on serum or cerebrospinal fluid in Moyamoya disease (MMD). Of 3,071 records identified, 31 studies were included.
October 20266
Urinary and sexual functional outcomes in female patients following elective lumbar spine surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis examined postoperative urinary and sexual functional outcomes in female patients undergoing elective lumbar fusion or disc replacement.
First-in-Human Phase 1b/2a Trial Shows Safety with MEK 1/2 Inhibitor EDV2209 as A Novel Treatment for Spontaneous Subarachnoid Hemorrhage.
The STOP-DCI first-in-human Phase 1b/2a interventional, randomized, double-blind, placebo-controlled trial evaluated intracerebroventricular EDV2209, a MEK 1/2 inhibitor, in patients with severe spontaneous subarachnoid…
Robot-assisted minimally invasive versus conventional open transforaminal lumbar interbody fusion for lumbar degenerative disease: a prospective randomized controlled trial.
This prospective, single-centre, assessor-blinded randomized trial compared robot-assisted minimally invasive TLIF with conventional fluoroscopy-guided open TLIF in 128 patients with lumbar degenerative disease.
Robot-assisted versus conventional cranial stereotactic neurosurgery: a systematic review and meta-analysis of targeting accuracy, procedural efficiency, and safety.
This systematic review and meta-analysis compared robot-assisted with conventional cranial stereotactic neurosurgery across 21 comparative studies, examining targeting accuracy, procedural efficiency, safety and…
Comparison of sterile silicone studs and scalp infiltration with lignocaine for the attenuation of the hemodynamic and stress response to skull pin insertion during craniotomy in pediatric neurosurgical patients: a randomized controlled trial : Sterile silicone studs versus lignocaine infiltration for skull pin insertion.
This randomized controlled trial compared sterile silicone studs (SSS) with lignocaine infiltration for skull pin insertion in 64 children aged 12 years or younger undergoing neurosurgery.
Virtual reality surgical simulator training of residents and early-career surgeons for pedicle screw placement: a systematic review and meta-analysis.
This systematic review and meta-analysis included six randomized controlled trials comparing virtual reality (VR) simulation with conventional teaching for pedicle screw placement training in residents and early-career…
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