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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchNeurosurgery

Efficacy and safety of middle meningeal artery embolisation for chronic subdural haematoma: a systematic review and meta-analysis of randomised controlled trials.

Neurosurg RevNov 11, 2026Open access

This PRISMA-compliant systematic review and meta-analysis pooled randomised controlled trials comparing middle meningeal artery embolisation (MMAE)-based treatment with standard management in adults with radiologically…

Why it matters

Treatment failure and repeat intervention are important outcomes in chronic subdural haematoma management. This synthesis of randomised evidence suggests MMAE-based treatment can reduce both, while the available trials…

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Also worth knowing

Clinical ResearchNeurologyOpen access

Subsequent epilepsy surgery after SEEG-guided radiofrequency thermocoagulation: Outcomes and prognostic value of treatment response-a systematic review and meta-analysis.

This systematic review and meta-analysis assessed outcomes after resective, disconnective, or ablative epilepsy surgery in patients previously treated with SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC), and…

Neurosurg RevNov 6, 2026Read summary
Clinical ResearchNeurosurgery

Salovum® reduces mortality in isolated severe traumatic brain injury: a randomized phase II trial.

This prospective, double-blind, placebo-controlled phase II randomized trial tested Salovum® in adults with isolated severe traumatic brain injury receiving intracranial pressure monitoring and neurointensive care at a…

BrainNov 4, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Perioperative neurocognitive outcomes after robot-assisted pelvic surgery: a systematic review and meta-analysis of reported proportions, comparative risk and prognostic factors.

This systematic review and meta-analysis examined delirium and cognitive decline after robot-assisted pelvic surgery in adults, including reported proportions, comparative risk, and prognostic factors.

J Robot SurgNov 11, 2026Read summary
Clinical ResearchOrthopedic Surgery

Paraspinal Muscle Quality and Functional Outcomes Following Lumbar Fusion: A Systematic Review.

This systematic review examined whether preoperative and postoperative paraspinal muscle quality is associated with patient-reported outcomes after lumbar interbody fusion, and whether findings differ between minimally…

Musculoskeletal CareNov 8, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed imaging methods for visualizing deep cerebral perforating arteries in human studies.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchNeurosurgery

Predictive Accuracy and Procedural Benefits of Software-Enhanced Flow-Diverter Planning: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed whether software simulations improve flow-diverter (FD) planning and procedural outcomes for intracranial aneurysms compared with physician planning.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Benson relaxation technique for perioperative anxiety and depressive symptoms in patients undergoing brain tumor surgery: a clinical trial.

This randomized controlled trial evaluated supervised Benson relaxation technique (BRT) sessions for perioperative anxiety and depressive symptoms in patients undergoing brain tumor resection.

Support Care CancerNov 3, 2026Read summary
Clinical ResearchNeurologyOpen access

Rescue treatment for medium vessel occlusion by intra-arterial tenecteplase: the RESCUE-TNK randomized clinical trial.

The RESCUE-TNK phase 2, multicentre randomised trial evaluated intra-arterial tenecteplase versus standard care in patients with acute ischaemic stroke caused by medium vessel occlusion.

Nat CommunNov 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Immunothrombosis Biomarkers and Multi-Omics Profiles After Successful Recanalization in Patients Receiving Ischemic Postconditioning: An Exploratory Analysis of the INSPIRE Trial.

This exploratory secondary analysis of the randomized INSPIRE trial examined 60 patients with ischemic stroke after successful endovascular thrombectomy recanalization.

Transl Stroke ResNov 3, 2026Read summary
Clinical ResearchNeurology

Germline Genetic Variants and Epilepsy Surgery Response: Individual Participant Pooled Analysis of 272 Patients.

This systematic review and individual-participant pooled analysis examined seizure outcomes after resection or laser ablation in 272 people with pathogenic or likely pathogenic germline epilepsy variants, excluding…

NeurologyNov 2, 2026Read summary
Clinical ResearchNeurologyOpen access

First-in-Human Phase 1b/2a Trial Shows Safety with MEK 1/2 Inhibitor EDV2209 as A Novel Treatment for Spontaneous Subarachnoid Hemorrhage.

The STOP-DCI first-in-human Phase 1b/2a interventional, randomized, double-blind, placebo-controlled trial evaluated intracerebroventricular EDV2209, a MEK 1/2 inhibitor, in patients with severe spontaneous subarachnoid…

Transl Stroke ResOct 30, 2026Read summary

Showing 12 of 20 publications that cleared our clinical screen in the last 14 days.

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