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266 articles

November 202612

Clinical ResearchNephrology

Thrombin-antithrombin complex and fibrinogen predict microangiopathic acute kidney injury in patients with traumatic injuries.

This secondary analysis of a single-center randomized controlled trial examined whether early coagulation and fibrinolysis biomarkers were associated with acute kidney injury (AKI) in adults with severe traumatic…

Blood AdvNov 12, 2026Read summary
Clinical ResearchCardiology

Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.

This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.

Eur Heart JNov 10, 2026Read summary
Clinical ResearchCardiology

Angiotensin receptor neprilysin inhibitors and renal outcomes in patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis examined renal outcomes with angiotensin receptor neprilysin inhibitors (ARNi) versus renin-angiotensin-aldosterone system inhibitors (RAASi) alone in patients with heart…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchCardiology

Effectiveness of nurse-led hypertension interventions on retention, adherence, and blood pressure control among adults in low- and middle-income countries: A systematic review.

This systematic review assessed nurse-led hypertension interventions in primary care among adults in low- and middle-income countries, examining retention, medication adherence, and blood pressure.

PLoS OneNov 5, 2026Read summary
Clinical ResearchNephrology

Effect of Kunxian capsule, a novel Tripterygium wilfordii preparation, on reducing proteinuria and slowing renal function decline in diabetic kidney disease: a 48-week randomized controlled trial.

This 48-week randomized controlled trial assigned 80 patients with diabetic kidney disease to irbesartan-based standard therapy with or without adjunctive Kunxian capsule.

Ren FailNov 4, 2026Read summary
Clinical ResearchNephrologyOpen access

Proton pump inhibitors in prevention of cisplatin-induced nephrotoxicity: a systematic review.

This systematic review assessed whether proton pump inhibitor (PPI) co-administration prevents cisplatin-related kidney injury and whether it is safe.

Support Care CancerNov 4, 2026Read summary
Clinical ResearchNephrology

Risk factors for cognitive impairment in patients undergoing hemodialysis: an umbrella review and meta-analysis.

This umbrella review and meta-analysis examined factors associated with cognitive impairment and cognitive frailty in adults receiving maintenance hemodialysis. It included five meta-analyses covering 97 associations.

Ren FailNov 3, 2026Read summary
Clinical ResearchNephrology

Exploratory serum renal biomarker and eGFR responses to high-protein diets during resistance versus concurrent training in resistance-trained men.

This randomized 2 × 2 factorial trial examined renal biomarkers and estimated glomerular filtration rate (eGFR) in resistance-trained men consuming 1.6 or 3.2 g·kg⁻¹·d⁻¹ of protein during 16 weeks of resistance or…

J Int Soc Sports NutrNov 3, 2026Read summary
Clinical ResearchGeriatricsOpen access

Dapagliflozin attenuates progression from prefrailty to frailty in patients with hypertension and chronic kidney disease.

DAPA-FORTRESS followed prefrail hypertensive adults aged over 65 years with chronic kidney disease (CKD) for 1 year to examine links between renal measures and physical performance, and whether dapagliflozin was…

J Clin InvestNov 2, 2026Read summary
Clinical ResearchNephrology

Role of magnesium as a protective agent in cisplatin-induced nephrotoxicity in head and neck cancer.

This randomized controlled trial evaluated intravenous magnesium sulfate for prevention of cisplatin-induced nephrotoxicity in 100 newly diagnosed patients with head and neck squamous cell carcinoma receiving concurrent…

Indian J PharmacolNov 2, 2026Read summary
Clinical ResearchNephrologyOpen access

Effects of a Nurse-Led Multicomponent Exercise Intervention for Haemodialysis Patients With Possible or Confirmed Sarcopenia: A Cluster Randomised Trial.

This cluster randomised trial evaluated a 12-week nurse-led multicomponent exercise programme in haemodialysis patients with possible or confirmed sarcopenia.

Nurs OpenNov 1, 2026Read summary
Clinical ResearchNephrologyOpen access

Transplantation of Hepatitis B Surface Antigen Positive or Viremic Kidneys: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed outcomes after transplantation of hepatitis B surface antigen-positive or viremic kidneys into non-viremic kidney transplant recipients.

Clin TransplantNov 1, 2026Read summary

October 202612

Clinical ResearchNephrology

Post-transplant follow-up for kidney transplant recipients: a systematic review of clinical practice guidelines.

This systematic review compared clinical practice guidelines for post-transplant follow-up of kidney transplant recipients, assessing methodological quality and recommendations for surveillance.

J NephrolOct 30, 2026Read summary
Clinical ResearchNephrology

Effects of a telehealth-supported home-based exercise program on functional capacity, sarcopenia risk, and patient-reported outcomes in non-dialysis stage 4-5 chronic kidney disease.

This prospective, parallel-group randomized controlled trial assessed a 12-week telehealth-supported home exercise program in adults aged ≥45 years with non-dialysis stage 4-5 chronic kidney disease.

J NephrolOct 30, 2026Read summary
Clinical ResearchNephrology

Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.

J NephrolOct 30, 2026Read summary
Clinical ResearchNephrology

Sexual dimorphism and age effects in CKD and type 2 diabetes in the CONFIDENCE trial.

This analysis of the randomized CONFIDENCE trial examined age- and sex-related differences in urinary albumin-to-creatinine ratio (UACR) changes among people with type 2 diabetes and chronic kidney disease receiving…

Nephrol Dial TransplantOct 30, 2026Read summary
Clinical ResearchCardiology

Acute declines in kidney function with thiazide plus loop diuretics versus loop diuretics alone in acute decompensated heart failure.

This analysis of the randomized CLOROTIC trial examined whether early eGFR changes were associated with outcomes in patients admitted with acute decompensated heart failure and randomized to thiazide or placebo…

Nephrol Dial TransplantOct 30, 2026Read summary
Clinical ResearchNephrology

Efficacy and Safety of Nafamostat Mesilate Injection in Patients Receiving Continuous Renal Replacement Therapy: A Meta-Analysis.

This meta-analysis assessed the efficacy and safety of nafamostat mesilate injection versus no anticoagulation in patients receiving continuous renal replacement therapy (CRRT).

J Vis ExpOct 30, 2026Read summary
Clinical ResearchCardiology

Oral Potassium Supplementation Lowers Clinic Blood Pressure in Untreated Primary Hypertension-Systematic Review and Meta-Analysis of Randomized Trials.

This systematic review and meta-analysis assessed oral potassium supplementation versus placebo, sodium chloride, or no treatment in adults with untreated primary hypertension.

J Am Heart AssocOct 30, 2026Read summary
Clinical ResearchCardiology

Efficacy of Stellate Ganglion Block for Preventing Postoperative Atrial Fibrillation After Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

This single-center, randomized, double-blind, placebo-controlled trial assessed whether preoperative ultrasound-guided right stellate ganglion block (SGB) prevents postoperative atrial fibrillation (POAF) in patients…

J Am Heart AssocOct 30, 2026Read summary
Clinical ResearchNephrology

Music-based interventions for people with kidney failure undergoing haemodialysis.

This Cochrane systematic review and meta-analysis assessed randomised trials of music-based interventions in people with kidney failure receiving haemodialysis.

Cochrane Database Syst RevOct 26, 2026Read summary
Clinical ResearchNephrology

Effects of E-Coach-Based Chronic Disease Management on Self-Management, Quality of Life, and Mental Health in Maintenance Hemodialysis Patients.

This randomized controlled trial evaluated a WeChat-based E-Coach programme in 96 patients receiving maintenance hemodialysis, comparing usual care plus E-Coach with usual care alone.

J Vis ExpOct 23, 2026Read summary
Clinical ResearchNephrology

Interim Analysis of a Phase 3 Trial of Povetacicept in IgA Nephropathy.

This prespecified interim analysis of an ongoing, multicenter, phase 3 randomized, double-blind, placebo-controlled trial evaluated povetacicept in participants with biopsy-proven IgA nephropathy receiving stable…

N Engl J MedOct 23, 2026Read summary
Clinical ResearchNephrology

Ravulizumab in IgA Nephropathy - Interim Analysis of a Phase 3 Trial.

This phase 3, multicenter, randomized, placebo-controlled trial evaluated intravenous ravulizumab every 8 weeks in adults with IgA nephropathy and persistent proteinuria despite standard therapy.

N Engl J MedOct 23, 2026Read summary

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