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283 articles
November 202616
Thrombocytapheresis for Extreme Thrombocytosis: A 20-Year Single-Center Experience With Acute and Chronic Use in Myeloproliferative Neoplasms.
Thrombocytapheresis is an established adjunctive therapy for rapid platelet cytoreduction in patients with extreme thrombocytosis, particularly in myeloproliferative neoplasms (MPNs), where it is typically used…
Multiorgan [ 18 F]florbetapir PET/CT uptake in multiple myeloma-associated systemic AL amyloidosis: a case report.
A 77-year-old man with multiple myeloma underwent whole-body [18F]florbetapir PET/CT because AL amyloidosis was suspected. The scan showed prominent tracer retention in the myocardium, thyroid, lungs, parotid glands…
Postpartum-acquired hemophilia A presenting as a recurrent rectus sheath hematoma following cesarean section: a case report.
A 30-year-old woman presented 17 days after an uncomplicated second cesarean section with severe abdominal pain and a rectus sheath hematoma.
Triple immune impairment in an elderly patient with IgG4-AIP and MGUS complicated by dual severe infections over 3 years: A case report.
An 82-year-old man with IgG4-related autoimmune pancreatitis and IgGλ monoclonal gammopathy of undetermined significance had markedly elevated serum IgG4 and a monoclonal paraprotein at baseline.
IgD-λ POEMS syndrome presenting with edema, pulmonary hypertension, and renal impairment: A case report.
A 38-year-old woman presented with years of intermittent leg edema, elevated creatinine, and acute worsening, followed by precapillary pulmonary hypertension, polyserous effusions, splenomegaly, lymphadenopathy, anemia…
Assay-aware flow-cytometric interpretation of relapsed B-cell precursor acute lymphoblastic leukemia after sequential CD19- and CD22-directed therapy: A case report.
A 73-year-old woman with B-cell precursor acute lymphoblastic leukemia developed marrow relapse after blinatumomab exposure.
Delayed pancytopenia following ingestion of wild mushrooms consistent with Hypholoma fasciculare: A case report.
A 57-year-old man presented with fever and generalized weakness about 10 days after eating self-collected wild mushrooms consistent with Hypholoma fasciculare. Testing showed delayed-onset pancytopenia.
A case report of ultra-rare SMARCD2 deficiency and review of the literature.
The report describes a patient with congenital neutropenia due to specific granule deficiency type 2, a syndromic autosomal recessive disorder associated with loss-of-function variants in SMARCD2.
Sirolimus-induced improvement of immune dysregulation associated hepatosplenomegaly in common variable immunodeficiency: a case-based review.
A 50-year-old woman with common variable immunodeficiency (CVID), treated with regular intravenous immunoglobulin replacement, developed progressive hepatosplenomegaly, cytopenias, abdominal enlargement, dyspnea…
Pseudo-Metabolic Alkalosis: A Hidden Laboratory Pitfall With Elevated LDH.
A 33-year-old man presented with progressive exertional dyspnea, syncope, and paresthesia. Testing showed pancytopenia, macrocytosis, LDH >3600 U/L, low haptoglobin, and vitamin B₁₂ <68 pg/mL, consistent with pernicious…
"Fatal venous thromboembolism and divergent phenotypes in DOCK8 deficiency: a three-sibling case series".
Three siblings with genetically confirmed DOCK8 deficiency had early-onset atopic dermatitis, recurrent respiratory infections, and failure to thrive. All developed bronchiectasis and severe viral infections.
Acquired haemophilia B in Kyasanur Forest disease: a case series of isolated prolonged activated partial thromboplastin time.
Nine patients with confirmed acute Kyasanur Forest disease had prolonged activated partial thromboplastin time (APTT) with normal prothrombin time.
Paraneoplastic Autoimmune Multiorgan Syndrome: Diagnostic Lessons for Pediatricians.
An 11-year-old boy developed subacute erythroblastopenia, followed by polymorphic mucocutaneous findings, severe myositis with a dermatomyositis-like phenotype, and mild hepatitis.
A Triad of Hematologic Diseases in a Military Member Requiring Splenectomy Case Report.
An active-duty servicemember with hereditary spherocytosis, sickle cell trait, and Factor VII deficiency developed recurrent, worsening pain crises after flights.
Preemptive Kidney Transplantation in a Pediatric Patient With Factor XI Deficiency: A Case Report.
A 14-year-old boy with end-stage renal disease from congenital posterior urethral valves underwent preemptive living-donor heterotopic kidney transplantation from his brother.
Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, and Skin Changes (POEMS) Syndrome With Characteristic Muscle Biopsy Findings and Without M-Protein.
A 63-year-old woman referred with presumed CIDP had not responded to IVIG or steroids. Her presentation included marked weight loss, papilledema, skin changes, thrombocytosis, thromboembolisms, hemi-diaphragmatic…
October 20268
Conservative management of disseminated intravascular coagulation caused by uterine leiomyoma degeneration in pregnancy: Case report and review.
A 35-year-old woman at 25 weeks’ gestation presented with lower abdominal pain and a tender 6.5 cm uterine leiomyoma; fetal well-being and placental appearance were normal on ultrasonography.
Haemodialysis in haemophilia B: a case report. Challenges and strategies from a nephrology perspective.
A 68-year-old man with severe haemophilia B and kidney failure required kidney replacement therapy. He received prophylactic Idelvion® (albutrepenonacog alfa), then underwent arteriovenous fistula creation and started…
Peritoneal Tuberculosis and Chronic Myeloid Leukaemia: A Case of Hickam's Dictum.
A 34-year-old man presented with persistent fever, ascites, thrombocytosis and clinical deterioration despite broad-spectrum therapy.
BILATERAL PARACENTRAL ACUTE MIDDLE MACULOPATHY IN A PEDIATRIC PATIENT WITH SICKLE CELL DISEASE.
An 8-year-old boy with HbSS sickle cell disease and no previous sickle cell retinopathy developed blurred vision, headache, photopsia, and metamorphopsia during an influenza A-associated upper respiratory illness.
Treatment of Crimean-Congo Hemorrhagic Fever With Supportive Care, Favipiravir, and Avatrombopag.
A patient with severe Crimean-Congo hemorrhagic fever was managed in a high-level isolation unit with supportive care, favipiravir, and avatrombopag.
Post-transplant BRAF/MEK inhibitor maintenance sustains complete remission in BRAF V600E-mutant histiocytic sarcoma.
A patient with refractory BRAF V600E-mutant histiocytic sarcoma achieved complete remission with BRAF/MEK inhibition and then underwent allogeneic stem cell transplantation.
Ravulizumab monotherapy for anti-CFH antibody-associated aHUS in an elderly patient: a case report highlighting individualized clinical decision-making.
An 85-year-old man presented with acute kidney injury, thrombocytopenia, microangiopathic hemolytic anemia, and severe hypertension.
Steroid-associated hypofibrinogenemia: an overlooked risk in graft-versus-host disease management after allogeneic hematopoietic stem cell transplantation.
A 47-year-old woman with acute myeloid leukemia developed late acute gastrointestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation and received methylprednisolone at 1 mg/kg/day.
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