Important medical research and remarkable case reports worth knowing.
Selected from high-relevance medical literature published in the last 14 days.
Two double-blind, placebo-controlled randomized trials evaluated plozasiran in 757 adults with severe hypertriglyceridemia.
Why it matters
Severe hypertriglyceridemia is associated with acute pancreatitis, and these trials found that plozasiran lowered triglyceride levels while the pooled analysis showed fewer pancreatitis events than with placebo.
This systematic review and meta-analysis assessed polyphenol interventions and gut microbiota and inflammatory biomarkers in people with overweight or obesity, drawing on 32 randomized controlled trials.
This individual patient data meta-analysis pooled cohort studies of patients with cirrhosis and portal vein thrombosis (PVT) who were not receiving anticoagulation.
This frequentist network meta-analysis compared seven pharmacological regimens for ulcer healing and prevention of delayed bleeding or perforation after gastric endoscopic submucosal dissection.
These European multidisciplinary practice guidelines address diagnosis and management of obstructed defecation syndrome (ODS).
This systematic review and meta-analysis examined randomized trials comparing follow-up protocols with versus without colonoscopy within 5 years after colorectal cancer surgery.
This systematic review and meta-analysis pooled placebo-controlled randomized trials of advanced therapies for perianal fistulizing Crohn’s disease.
This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.
This randomized controlled trial assessed daily physical activity and abdominal pain in girls aged 9 to 13 years with functional abdominal pain disorders who participated in an 8-month dance and yoga intervention.
This double-blind, three-arm randomised dietary intervention compared four weeks of pea protein concentrate (PPC), pea protein isolate (PPI), or whey protein isolate (WPI) supplementation in healthy adults.
This systematic review and meta-analysis assessed imaging-based AI models for predicting pathological complete response after neoadjuvant therapy for esophageal cancer, separating internal from external validation.
This consensus statement addresses diagnosis and management of achalasia in children, for whom pediatric-specific guidelines were lacking.
Showing 12 of 26 publications that cleared our clinical screen in the last 14 days.
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