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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportOncology (Medical)

Synchronous hepatocellular carcinoma and nasopharyngeal carcinoma in a patient with chronic hepatitis B: A case report and literature review.

Medicine (Baltimore)Nov 6, 2026

A 63-year-old Chinese man with chronic hepatitis B was found on routine screening to have a liver mass and reported nasal obstruction.

Clinical pearl

A liver mass and nasal obstruction in a patient with chronic hepatitis B may reflect synchronous primary cancers; tissue confirmation established distinct hepatocellular and nasopharyngeal malignancies in this case.

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Also worth knowing

Case ReportGastroenterology

Triple immune impairment in an elderly patient with IgG4-AIP and MGUS complicated by dual severe infections over 3 years: A case report.

An 82-year-old man with IgG4-related autoimmune pancreatitis and IgGλ monoclonal gammopathy of undetermined significance had markedly elevated serum IgG4 and a monoclonal paraprotein at baseline.

Medicine (Baltimore)Nov 6, 2026Read case
Case ReportAllergy & Immunology

Sirolimus-induced improvement of immune dysregulation associated hepatosplenomegaly in common variable immunodeficiency: a case-based review.

A 50-year-old woman with common variable immunodeficiency (CVID), treated with regular intravenous immunoglobulin replacement, developed progressive hepatosplenomegaly, cytopenias, abdominal enlargement, dyspnea…

Rheumatol IntNov 5, 2026Read case
Case ReportPediatrics

Excellent Long-Term Outcome in a Staged, Simultaneous Liver-Kidney Transplantation of a Highly Sensitized Pediatric Patient With B and T Cell Positive Crossmatch.

A highly sensitized small child with high-titer class I and II donor-specific antibodies underwent staged simultaneous liver-kidney transplantation from the same donor despite a positive cytotoxic crossmatch.

Pediatr TransplantNov 1, 2026Read case
Case ReportOncology (Medical)

Resolution of Severe Jaundice Following Hepatic Artery Infusion of Bevacizumab and 5-Fluorouracil With Oral Regorafenib in Metastatic Colorectal Cancer：A Case Report.

A patient with sigmoid colon cancer and recurrent liver metastases, previously treated with surgery, systemic chemotherapy, transcatheter arterial chemoembolization, and radiotherapy, presented with severe jaundice.

Am J Case RepNov 4, 2026Read case
Case ReportMedical GeneticsOpen access

Severe Atherogenic Dyslipidemia in Ataxia-Telangiectasia Despite Cachexia: Mechanistic Insights into Mitochondrial Dysfunction.

A 25-year-old woman with genetically confirmed ataxia-telangiectasia and extreme underweight (body mass index 12.5 kg/m²) developed severe mixed atherogenic dyslipidemia despite modest dietary fat intake and no…

Yale J Biol MedNov 4, 2026Read case
Case ReportGastroenterology

Submucosal Tunnel Endoscopic Resection of a Gastric Schwannoma Mimicking a Submucosal Tumor.

A 73-year-old woman with recurrent abdominal distension was found on esophagogastroduodenoscopy to have an 8.2 mm submucosal lesion in the gastric body.

J Vis ExpNov 3, 2026Read case
Case ReportObstetrics & Gynecology

Cesarean Delivery After Multiple Prior Intraperitoneal Surgeries: A Case Report in a Patient With Crohn Disease.

A 25-year-old woman with Crohn disease in sustained remission had an uncomplicated pregnancy after in vitro fertilization. Her history included five intraperitoneal operations, including bilateral hemicolectomy…

Am J Case RepNov 1, 2026Read case
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