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257 articles
November 202611
Thrombin-antithrombin complex and fibrinogen predict microangiopathic acute kidney injury in patients with traumatic injuries.
This secondary analysis of a single-center randomized controlled trial examined whether early coagulation and fibrinolysis biomarkers were associated with acute kidney injury (AKI) in adults with severe traumatic…
Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.
Efficiency of Rescue Paramedic Hoist versus Underslung Antenna in Helicopter-Based Avalanche Searches: A Randomized Trial.
This randomized experimental field trial compared helicopter-based avalanche transceiver searches using an underslung antenna or a hoisted rescue paramedic with a handheld transceiver.
Salovum® reduces mortality in isolated severe traumatic brain injury: a randomized phase II trial.
This prospective, double-blind, placebo-controlled phase II randomized trial tested Salovum® in adults with isolated severe traumatic brain injury receiving intracranial pressure monitoring and neurointensive care at a…
Tenecteplase Before Thrombectomy at 4.5 to 24 Hours for Basilar Artery Occlusion: The ATTENTION LATE Randomized Clinical Trial.
This multicenter, open-label, blinded-endpoint randomized clinical trial compared intravenous tenecteplase before endovascular thrombectomy (EVT) with EVT alone in patients with moderate to severe basilar artery…
Short-Term Pain Outcomes of Trigger Point Injection Versus Dry Needling for Acute Myofascial Low Back Pain in the Emergency Department: A Prospective Randomized Comparative Study.
This prospective randomized comparative study evaluated trigger point injection versus dry needling for acute myofascial low back pain in emergency department patients.
Prehospital Pediatric Ventilation Quality Following Use of a Feedback Device: A Randomized Study.
This multicenter, single-anonymized randomized crossover simulation study assessed pediatric manual ventilation by EMS clinicians at 5 agencies across 3 US metropolitan sites.
Telehealth Treatment of Anxiety in Patients With Low-Risk Chest Pain in the Emergency Department: The PACER Randomized Clinical Trial.
The PACER multicentre, three-group randomised comparative effectiveness trial tested peer-supported internet-based cognitive behavioural therapy (iCBT) and therapist-delivered telehealth CBT against primary care…
Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.
This two-arm randomized clinical trial tested IntERact, a 30-day program combining telehealth behavioral counseling and tailored smartphone content, against enhanced usual care among 373 emergency department patients…
Performance of the i-Gel Versus King LT-D by Combat Medics Under Simulated Tactical Conditions: A Prospective Randomized Crossover Study.
This prospective randomized crossover study compared i-gel and King LT-D placement by active-duty combat medics after exertion while wearing full combat gear, using a high-fidelity manikin.
Pain-Related Outcome Domains and Measures in Randomized Controlled Trials of Treatment for Acute Abdominal Pain: A Systematic Review.
This PRISMA-guided systematic review mapped pain-related outcome domains and measures in randomized controlled trials of acute abdominal pain treatment.
October 202613
Prehospital Analgesia in Trauma: A Systematic Review of Current Evidence.
This systematic review assessed the safety and effectiveness of pharmacologic analgesia given before hospital arrival to acutely injured adults aged over 15 years.
Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials.
This systematic review and individual participant data meta-analysis combined five randomised trials comparing 0/1 h with 0/3 h cardiac troponin pathways in patients presenting with suspected myocardial infarction.
Diagnostic accuracy of high-sensitivity point-of-care troponin assays in emergency department for patients presenting with chest pain: a systematic review.
This systematic review assessed the diagnostic accuracy of four commercially available high-sensitivity point-of-care troponin assays in adults presenting to emergency departments with chest pain suggestive of acute…
Jidesheng Snake Pills as Adjunctive Therapy for Snakebite: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis assessed randomized evidence for Jidesheng Snake Pills as adjunctive treatment for snakebite. Five unique trials involving 458 participants were included.
Prediction of death by neurologic criteria in patients with non-traumatic acute brain injury: a systematic review and meta-analysis.
This systematic review and meta-analysis examined predictors of death by neurologic criteria (DNC) after non-traumatic acute brain injury.
A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.
This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.
POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.
This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.
Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.
Acute management of pelvic ring injuries: identifying common treatment principles across institutional algorithms.
This PRISMA-guided systematic review compared published institutional algorithms for acute pelvic ring injury management. Searches identified 25 studies describing algorithms, pathways, or protocols published from 2006…
Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysis.
This Bayesian network meta-analysis compared reperfusion strategies in imaging-selected patients with acute ischemic stroke treated 4.5 to 24 hours after onset or last known well.
Neutrophil to lymphocyte ratio for predicting delayed neurologic sequelae caused by carbon monoxide poisoning: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether the neutrophil-to-lymphocyte ratio (NLR) predicts delayed neurologic sequelae (DNS) after acute carbon monoxide poisoning.
Anxiety in patients with cancer and emergency department use: a systematic review.
This systematic review examined whether anxiety is associated with subsequent emergency department (ED) use among adults with cancer.
Efficacy of Ibuprofen Versus Acetaminophen for Acute Fever Management in Febrile Children: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials compared ibuprofen with acetaminophen for acute fever management in children. Seven studies contributed to the quantitative synthesis.
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