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370 articles

November 202622

Clinical ResearchNeurology

Cutaneous Silent Period-Based Comparison of Dorsal Root Ganglion Pulsed Radiofrequency and Transforaminal Epidural Steroid Injection in Lumbar Radicular Pain: A Randomized Controlled Trial.

This prospective, single-blind randomized controlled trial compared dorsal root ganglion pulsed radiofrequency (DRG-PRF) with transforaminal epidural steroid injection (TFESI) in 36 patients with chronic unilateral…

Clin J PainNov 11, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

The unseen risk: a systematic review of the incidence, management, and outcomes of the trigeminocardiac reflex in skull-base surgery.

This PRISMA-guided systematic review synthesized reports of intraoperative trigeminocardiac reflex (TCR) during skull-base and adjacent neurosurgical procedures.

Neurosurg RevNov 11, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Perioperative neurocognitive outcomes after robot-assisted pelvic surgery: a systematic review and meta-analysis of reported proportions, comparative risk and prognostic factors.

This systematic review and meta-analysis examined delirium and cognitive decline after robot-assisted pelvic surgery in adults, including reported proportions, comparative risk, and prognostic factors.

J Robot SurgNov 11, 2026Read summary
Clinical ResearchAnesthesiology

Oliceridine vs Sufentanil Combined With Ondansetron for Postoperative Nausea and Vomiting and QTc Interval in Hysteroscopic Surgery: A Prospective Randomized Controlled Study.

This prospective, randomized, double-blind controlled study compared oliceridine plus ondansetron with sufentanil plus ondansetron in 62 patients undergoing non-intubated hysteroscopic surgery under general anesthesia.

Med Sci MonitNov 10, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Acupuncture after surgery of soft tissue tumors of the extremities: postoperative pain and feasibility: a prospective trial.

This prospective, single-arm, single-centre pilot study assessed acupuncture feasibility and postoperative pain after extremity soft tissue tumor resection in 25 patients.

Langenbecks Arch SurgNov 10, 2026Read summary
Clinical ResearchAnesthesiology

Discontinuation of renin-angiotensin system inhibitors before non-cardiac surgery: a meta-analysis.

This systematic review and meta-analysis of five randomized controlled trials compared discontinuation with continuation of renin-angiotensin system inhibitors before non-cardiac, non-vascular surgery.

Eur Heart JNov 6, 2026Read summary
Clinical ResearchAnesthesiology

Effects of opioid-free and opioid-sparing anesthesia on postoperative delirium: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed opioid-free and opioid-sparing anesthesia for preventing postoperative delirium (POD) in adult surgical patients.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchAnesthesiology

Thoracic epidural versus paravertebral blockade for reducing chronic post-thoracotomy pain (TOPIC-2): open label, parallel group, superiority, multicentre, randomised controlled trial.

This open-label, multicentre, parallel-group superiority randomised trial compared perioperative paravertebral blockade with thoracic epidural in adults undergoing thoracotomy at 15 UK centres.

BMJNov 5, 2026Read summary
Clinical ResearchAnesthesiology

Perioperative respiratory adverse events in children undergoing adenotonsillectomy with laryngeal mask airway versus endotracheal tube ventilation: multicentre, randomised controlled trial.

This multicentre, randomised, parallel-group trial compared laryngeal mask airway (LMA) with endotracheal tube (ETT) ventilation during adenotonsillectomy under general anaesthesia in 400 children aged 2 to under 7…

BMJNov 4, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Liposomal Bupivacaine versus Ropivacaine for Rhomboid Intercostal and Subserratus Plane Blocks in Video-Assisted Thoracoscopic Surgery: A Randomised Controlled Trial.

This single-centre randomised controlled trial compared liposomal bupivacaine (LB) with ropivacaine (RP) for ultrasound-guided rhomboid intercostal and subserratus plane blocks in patients undergoing video-assisted…

Drug Des Devel TherNov 4, 2026Read summary
Clinical ResearchPulmonologyOpen access

The Association Between Chronic Obstructive Pulmonary Disease and Postoperative Delirium: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether chronic obstructive pulmonary disease (COPD) is associated with postoperative delirium (POD) in surgical patients.

Int J Chron Obstruct Pulmon DisNov 4, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Benson relaxation technique for perioperative anxiety and depressive symptoms in patients undergoing brain tumor surgery: a clinical trial.

This randomized controlled trial evaluated supervised Benson relaxation technique (BRT) sessions for perioperative anxiety and depressive symptoms in patients undergoing brain tumor resection.

Support Care CancerNov 3, 2026Read summary
Clinical ResearchAnesthesiology

The Effect of Perioperative Video Interventions on Postoperative Pain Control: A Systematic Review.

This systematic review examined randomized controlled trials of perioperative video interventions in adult surgical patients, assessing postoperative pain intensity and analgesic consumption.

Acta Anaesthesiol ScandNov 2, 2026Read summary
Clinical ResearchAnesthesiology

Comparison of the opioid-sparing effects of a combination of dexamethasone, paracetamol, and ketorolac versus paracetamol and ketorolac in patients undergoing total laparoscopic hysterectomy: A prospective double-blind randomized controlled trial.

This prospective, double-blind randomized controlled trial compared adding intravenous dexamethasone to paracetamol and ketorolac with paracetamol and ketorolac alone in 100 women aged 18–60 years with ASA I–II status…

Indian J PharmacolNov 2, 2026Read summary
Clinical ResearchUrologyOpen access

Tetracaine hydrochloride gel delays and reduces catheter-related bladder discomfort after transurethral resection: a randomized controlled trial.

This randomized, single-blind trial compared tetracaine hydrochloride gel with standard lubricant in 130 patients undergoing transurethral resection.

PeerJNov 2, 2026Read summary
Clinical ResearchPulmonologyOpen access

Airway occlusions to measure inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation.

This multicenter randomized study assessed whether airway occlusion maneuvers can estimate inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation (NIV).

Am J Respir Crit Care MedNov 1, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Dermabond versus suture fixation for spinal cord stimulator trial lead anchoring: a randomized within-patient controlled trial.

This prospective, randomized within-patient controlled trial compared Dermabond with suture for anchoring bilateral thoracic percutaneous spinal cord stimulator trial leads in 48 adults.

Pain MedNov 1, 2026Read summary
Clinical ResearchEmergency Medicine

Performance of the i-Gel Versus King LT-D by Combat Medics Under Simulated Tactical Conditions: A Prospective Randomized Crossover Study.

This prospective randomized crossover study compared i-gel and King LT-D placement by active-duty combat medics after exertion while wearing full combat gear, using a high-fidelity manikin.

Mil MedNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Pain-Related Outcome Domains and Measures in Randomized Controlled Trials of Treatment for Acute Abdominal Pain: A Systematic Review.

This PRISMA-guided systematic review mapped pain-related outcome domains and measures in randomized controlled trials of acute abdominal pain treatment.

Eur J PainNov 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

The Effect of Virtual Reality on Anxiety and Vital Signs in Patients Undergoing Total Knee Replacement Surgery: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether intraoperative virtual reality affected anxiety and vital signs in 70 patients undergoing total knee replacement.

Comput Inform NursNov 1, 2026Read summary
Clinical ResearchNeurology

The Impact of Outcome Measures for Responder Analyses in Placebo-Controlled Trials of Pharmacological Treatments for Neuropathic Pain.

This meta-analysis examined how dichotomous responder definitions affect estimated treatment effects in placebo-controlled pharmacological trials for neuropathic pain.

Eur J PainNov 1, 2026Read summary

October 20262

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