Trending archive
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1382 articles
October 202624
Focal Epithelial Hyperplasia in a Somali Child: A Case Report and Review of Management with Topical Imiquimod.
An 8-year-old Somali girl had a 3.5-year history of asymptomatic, progressively increasing oral lesions. Examination showed multiple soft, flat-topped verrucous papules on the lower labial, buccal and lingual mucosa and…
Optimization of Anticoagulation Strategy During Cardiopulmonary Bypass in Neonates with Congenital Heart Disease: A Randomized Controlled Trial.
Neonatal hemostatic immaturity complicates anticoagulation during cardiopulmonary bypass (CPB). Current practice largely follows the strategy of 400 U/kg from adult protocols, as neonatal-specific guidelines and…
Giant Cystic Lymphangioma of the Transverse Mesocolon in a 7-Year-Old Child: A Case Report.
A 7-year-old girl presented with several weeks of vomiting, abdominal pain and progressive distension. Examination found a large abdominal mass; laboratory results were unremarkable.
Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.
A 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation had previously been unable to tolerate oral or intramuscular preoperative sedation because of agitation and physical aggression.
Aberrant splicing caused by a homozygous AK2 c.498 + 1G > A variant in a patient with reticular dysgenesis and concurrent B-cell acute lymphoblastic leukemia.
A boy with reticular dysgenesis (RD), a severe immunodeficiency associated with biallelic AK2 loss of function, was also diagnosed with B-cell acute lymphoblastic leukemia (B-ALL).
Prenatal Diagnosis of Pulmonary Arteriovenous Malformation With 3D/4D STIC Fetal Echocardiography.
A fetus was diagnosed with pulmonary arteriovenous malformation at 21 weeks’ gestation during fetal echocardiography. Color Doppler showed turbulent swirling flow in the right pulmonary vein, and spectral Doppler…
Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…
Cost comparison of the ShangRing device versus Mogen clamp for early infant male circumcision in Sub-Saharan Africa.
This cost comparison alongside a randomized controlled trial assessed early infant male circumcision using the ShangRing (SR) versus the Mogen clamp (MoC) among infants aged 0–60 days in Kenya, Tanzania, and Uganda.
Daily Zinc Supplementation for Infection Prevention in Children With Sickle Cell Anemia: The ZIPS-2 Randomized Clinical Trial.
The ZIPS-2 randomized, double-blind, placebo-controlled trial evaluated daily zinc for infection prevention in children aged 1 to 4.99 years with sickle cell anemia in Uganda.
Adenotonsillectomy for children with mild sleep-disordered breathing: who benefits?
This secondary analysis of a 12-month, multicentre randomised trial examined children aged 3.0–12.9 years with mild sleep-disordered breathing, comparing early adenotonsillectomy (eAT) with watchful waiting and…
Impact of a Dynamic Visualized Pain Assessment Tool on Pediatric Pain Management: A Stepped-Wedge Cluster Randomized Trial.
This stepped-wedge cluster randomized trial evaluated a dynamic visualized pain assessment tool across five clinical wards, involving 15 infants and 45 video segments spanning baseline, procedural pain, and…
Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.
A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.
Comparative effects of non-pharmacological intervention categories on cognitive domains in children with autism spectrum disorder: A systematic review and network meta-analysis of randomized controlled trials.
This systematic review and network meta-analysis compared non-pharmacological intervention categories for cognitive outcomes in children with autism spectrum disorder, drawing on randomized controlled trials.
Efficacy of Ibuprofen Versus Acetaminophen for Acute Fever Management in Febrile Children: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials compared ibuprofen with acetaminophen for acute fever management in children. Seven studies contributed to the quantitative synthesis.
Differential changes in frontolimbic functional connectivity following 12-week psychostimulant monotherapy in ADHD youth with and without familial risk for bipolar I disorder.
This randomized controlled trial examined whether 12 weeks of psychostimulant monotherapy was associated with different changes in amygdala–ventrolateral prefrontal cortex functional connectivity in youth with ADHD…
Home visits following hospital discharge for families with preterm and low-birthweight infants.
This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.
Robotic Parenchyma-Preserving Pancreatic Resection for Focal Congenital Hyperinsulinism in an Infant.
An infant weighing 4.6 kg with focal congenital hyperinsulinism underwent robot-assisted, parenchyma-preserving pancreatic resection using indocyanine green, intraoperative ultrasound, and suture-based retraction.
Use of Instructional Therapeutic Play during the preoperative nursing consultation of a child with orofacial clefts.
An 8-year-old girl with an orofacial cleft was preparing for cleft palate repair and expressed fear and anxiety about surgery, especially that she might not wake up after anesthesia.
Effect of Oliceridine on Early Postoperative Recovery in Children Undergoing Adenotonsillectomy: A Prospective, Double-Blind, Randomized Controlled Trial.
Children undergoing adenotonsillectomy may be vulnerable to opioid-related adverse effects, creating a need for analgesic strategies that support rapid postoperative recovery.
Assessment of Autism Spectrum Disorder in Gender-Diverse Populations: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined how autism spectrum disorder (ASD) and autistic traits are assessed in gender-diverse populations.
Assisted Reproductive Technology and Risk of Congenital Heart Defects in the Offspring: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed congenital heart defect (CHD) risk in offspring conceived through assisted reproductive technology (ART) compared with spontaneous conception.
Detection of MOG-IgG and MOG-IgA in Maternal Breast Milk and Infant Blood in MOGAD: A Case Report.
A mother with MOG antibody-associated disease had persistently elevated plasma MOG-IgG, with a transient decrease in early pregnancy.
Effect of Digital Technology-Based Interventions on Core Symptoms and Cognitive Function in Children With Attention-Deficit/Hyperactivity Disorder: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 37 randomized controlled trials of digital interventions for children with ADHD, covering computer-based interventions, serious video games, exergames, and virtual…
Concurrent biliary atresia and intestinal atresia: a systematic review of clinical characteristics, pathogenesis, management, and outcomes.
This systematic review examined clinical features, management, and outcomes in patients with concurrent biliary atresia (BA) and intestinal atresia (IA), drawing on case reports, case series, and retrospective reviews.
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