Trending archive
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464 articles
August 202624
Comparative Effectiveness of Chlorthalidone Versus Hydrochlorothiazide and Dose-Response of Amiloride on Blood Pressure and Biochemical Parameters.
This 12-week factorial randomized clinical trial compared chlorthalidone 25 mg with hydrochlorothiazide 50 mg, and amiloride 5 mg with 10 mg, assessing office and ambulatory blood pressure and laboratory parameters.
Acute water ingestion influences lean soft tissue estimation from dual-energy x-ray absorptiometry: Implications for clinical diagnosis.
This randomized controlled trial investigated the effects of acute water ingestion (AWI) on dual-energy X-ray absorptiometry (DXA) estimates of lean soft tissue (LST) in 46 participants.
Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk.
This multicenter randomized controlled trial evaluated the efficacy of direct oral anticoagulant (DOAC) therapy in patients with atrial fibrillation at intermediate stroke risk in South Korea.
Acetazolamide mitigates opioid-associated sleep-disordered breathing.
This randomized controlled trial investigated the effects of oral acetazolamide on sleep-disordered breathing (SDB) in nine adults with opioid-associated SDB.
Traditional, complementary, and integrative medicine therapies for mild/moderate acute COVID-19: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the effectiveness of Traditional, Complementary, and Integrative Medicine (TCIM) therapies for mild/moderate acute COVID-19 in 18,627 patients across 69 trials.
Kratom-Associated Pulmonary Toxicity: A Systematic Review of Case Reports and Forensic Series with a Proposed Clinical Phenotype Classification.
Kratom use has increased, including concentrated 7-hydroxymitragynine products, but pulmonary toxicity has not been systematically synthesized.
Effect of diet macronutrient content on the cardiometabolic response to weight loss: A randomized clinical trial.
This randomized clinical trial examined the impact of different macronutrient compositions in diets on cardiometabolic responses to moderate weight loss in individuals with metabolically unhealthy obesity.
Achieved home systolic blood pressure and cardiovascular risk in older hypertensive patients.
This secondary analysis of a randomized controlled trial examined achieved home systolic blood pressure (SBP) and cardiovascular outcomes in older adults with hypertension.
Effectiveness of Antiseptic and Antibiotic Use to Prevent Central Line-Associated Bloodstream Infections in ICU Patients: A Systematic Review and Narrative Synthesis of Randomized Clinical Trials.
This systematic review evaluated the effectiveness of antiseptics and antibiotics in preventing central line-associated bloodstream infections (CLABSI) in ICU patients.
Butyrylcholinesterase Activity as a Mortality Marker in ICU Patients: An Individual Participant Data Meta-Analysis.
This meta-analysis evaluated the prognostic value of butyrylcholinesterase (BChE) activity for in-hospital mortality in critically ill adults, primarily those with sepsis.
Effect of Peer Comparison Feedback and Professional Norms on Vitamin D Testing and Generic Medication Prescribing.
This randomized controlled trial evaluated the impact of peer comparison feedback on vitamin D testing and generic medication prescribing among primary care physicians in Switzerland.
Cardiorespiratory and Metabolic Responses After Sleeve Gastrectomy in Adults With Obesity: Systematic Review.
This systematic review examined cardiorespiratory and metabolic responses after sleeve gastrectomy in adults with obesity. It included seven observational reports involving 162 participants from two independent cohorts…
Additional blood-pressure-lowering effect of exercise in adults on stable antihypertensive medication: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis pooled randomised controlled trials of exercise in adults taking stable antihypertensive medication.
Assessment of the safety and efficacy of sodium pentaborate pentahydrate in individuals with overweight and obesity: a randomized, double-blind, placebo-controlled, phase 1/2 dose-finding trial.
This randomized, double-blind, placebo-controlled phase 1/2 trial evaluated the safety and preliminary efficacy of sodium pentaborate pentahydrate in 177 adults with overweight or obesity over 12 weeks.
Protein requirements and determinants of protein catabolic rate in critically ill patients with acute kidney injury: A post hoc analysis of the ENGINE randomized controlled trial.
This post hoc analysis of the ENGINE randomized controlled trial evaluated protein requirements in 78 critically ill patients with acute kidney injury (AKI).
Quadriceps muscle behavior assessed by ultrasound in septic patients: A systematic review.
This systematic review examined the use of ultrasound to assess quadriceps muscle atrophy in adults with sepsis or septic shock in ICUs.
Association between seminal and serum iron parameters and male infertility: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between iron levels and male infertility, analyzing data from ten studies with 985 participants.
Effects of diabetes, obesity, and metabolic syndrome on alcohol-associated liver disease: A systematic review.
This systematic review evaluated the impact of cardiometabolic risk factors (CMRFs) on clinical outcomes in adults with alcohol-associated liver disease (ALD).
Food intake sequence affects postprandial metabolic, hormonal, and appetite responses in healthy male football players: A randomised crossover trial.
This randomized crossover trial examined the effects of food intake sequence on postprandial responses in 14 highly trained male football players.
Severe Disseminated Melioidosis with Pulmonary, Cutaneous, and Osteoarticular Involvement in the Peruvian Amazon.
A 35-year-old man with poorly controlled diabetes living in the Peruvian Amazon presented with multifocal pneumonia, bacteremia, and septic shock requiring mechanical ventilation and vasopressors.
Association Between Follow-Up Mean Blood Pressure and Blood Pressure Control: A Meta-Regression Analysis of 101 Randomized Trials.
This meta-regression analysis examined the relationship between mean blood pressure (BP) and BP control in 101 randomized trials involving over 85,000 participants.
Programmatic effectiveness of tuberculosis preventive treatment for people with HIV in six high-tuberculosis-burden countries (PROTECT): a prospective cohort study and meta-analysis.
This prospective cohort study and meta-analysis evaluated the effectiveness of tuberculosis preventive treatment (TPT) in reducing tuberculosis incidence and all-cause mortality among 235,424 people with HIV initiating…
Toward a standardized framework for chronic obstructive pulmonary disease self-care: An umbrella review.
This umbrella review synthesized international COPD guidelines and systematic reviews to define core components of COPD self-care and assess their alignment with guidance.
Shared Decision-Making and the Role of Maternalism in Resolving Difficult End-of-Life Decisions.
We explore the spectrum of shared decision-making, especially the idea of maternalism, which combines patient or surrogate preferences and goals with the clinician's responsibility to provide care within the boundaries…
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