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2000 articles
June 202624
A phase 1 dose-finding and pharmacokinetic study of acasunlimab alone or in combination with pembrolizumab in Japanese patients with advanced or metastatic solid tumors.
This phase 1, open-label, dose-escalation trial assessed the safety and pharmacokinetics of acasunlimab, both alone and in combination with pembrolizumab, in Japanese patients with advanced or metastatic solid tumors.
Matching-Adjusted Indirect Comparison of Tarlatamab for Patients with Platinum-Refractory or Platinum-Resistant Extensive-Stage Small-Cell Lung Cancer.
This study conducted a matching-adjusted indirect comparison of tarlatamab versus paclitaxel and CAV in patients with platinum-refractory or platinum-resistant extensive-stage small-cell lung cancer (ES-SCLC).
Intense Incidental F-18 DOPA Uptake in Low-grade Prostate Adenocarcinoma: A Potential Diagnostic Pitfall.
A 60-year-old man presented for evaluation of elevated normetanephrines, during which intense incidental F-18 DOPA uptake was noted in the prostate on PET/CT.
Atypical Grover Disease Associated With Merkel Cell Carcinoma: A Novel Paraneoplastic Presentation.
A 63-year-old man presented with four months of generalized, pruritic papules. Biopsy showed focal intraepidermal acantholysis and dyskeratosis with patchy vacuolar interface change; direct immunofluorescence was…
Synchronous Small Cell and Adenocarcinoma of the Lung Integrating Morphology and Molecular Profiling: A Case Report.
A 61-year-old woman had two synchronous right upper-lobe tumors, both staged pT1bN0M0: a combined small cell lung carcinoma (SCLC) with adenocarcinoma, and a separate invasive adenocarcinoma.
The Role of STAG2, CDKN2A, and TP53 Genes in Ewing Sarcoma: A Report of a Rare Case of Primary Ewing Sarcoma of the Kidney With Favorable Outcome.
A pediatric patient presented with stage IV primary Ewing sarcoma of the kidney, a rare and aggressive malignancy. The patient underwent upfront surgical resection followed by radiation therapy, resulting in a durable…
The clinical relevance of regional lymph node microarchitecture in oesophageal cancer patients - Results from the UK MRC OE02 trial.
This randomized controlled trial examined the impact of neoadjuvant chemotherapy on lymph node microarchitecture in 333 oesophageal cancer patients.
Comparison of the Effects of Intraoperative Pectoral Nerve Block and Local Wound Infiltration in Pain Management for Breast Cancer Surgery: A Randomized Controlled Trial.
This randomized controlled trial evaluated the analgesic effects of intraoperative pectoral nerve block (PECS) versus local wound infiltration in mastectomy patients.
Pilates versus Gyrotonic Expansion System on chemotherapy-induced peripheral neuropathy and fall risk.
This randomized controlled trial compared the effects of Pilates and Gyrotonic Expansion System (GES) on chemotherapy-induced peripheral neuropathy (CIPN) and fall risk in 96 cancer survivors.
Quizartinib in Combination With FLAG-IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG-QUIDA): A PETHEMA Phase I-II Trial.
The FLAG-QUIDA trial, a multicenter phase I/II study, evaluated quizartinib combined with FLAG-IDA in adults with relapsed or refractory acute myeloid leukemia (AML).
Clinical Features, Treatment, and Outcomes for Oropharyngeal Adenoid Cystic Carcinoma: A Systematic Review.
This systematic review analyzed 44 studies involving 195 patients with oropharyngeal adenoid cystic carcinoma to describe clinical features, treatments, and outcomes.
Does the prophylactic use of compression garments reduce the risk of lower limb lymphedema after pelvic and/or inguinal lymphadenectomy for gynecological cancer? A systematic review.
This systematic review evaluated the effectiveness of prophylactic compression garments in reducing lower-limb lymphedema after pelvic and/or inguinal lymphadenectomy in women with gynecological cancer.
Epileptogenic Brain Metastasis Early Positive on 18 FDG PET/CT Compared to MRI.
A 61-year-old woman with metastatic small cell lung carcinoma presented with a persistent tremor in her right upper limb. Initial brain MRI results were normal, but 18 F-FDG PET/CT revealed hypermetabolism in the left…
18 F-MFBG Uptake From Multiple Focal "Hot Spots" to Superscan in a Pediatric Patient With High-risk Neuroblastoma.
A 5-year-old girl with high-risk neuroblastoma presented for 18 F-MFBG PET/CT, which revealed multiple discrete focal 'hot spots.' Bone marrow aspiration confirmed metastatic involvement.
99m Tc‑FAPI‑46 Scintigraphy for Staging of Non-Small Cell Lung Carcinoma.
A 71-year-old man with squamous cell lung carcinoma underwent staging with CT and 99m Tc-MDP bone scintigraphy, which indicated limited skeletal involvement.
Extracranial Meningiomas of the Left Neck.
A 64-year-old woman presented with an extracranial meningioma in the left side of her neck. Histological examination and immunohistochemical staining confirmed the diagnosis.
Residual disease after radiologically complete vacuum-assisted breast excision in patients with ductal carcinoma in situ: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the rates of residual disease and upstaging to invasive carcinoma following radiologically complete vacuum-assisted breast excision (VABE) in patients with ductal…
Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.
This retrospective clinicopathological review describes seven women aged 45–74 years with malignant adenomyoepithelioma (M-AME) of the breast.
Spontaneous regression of colorectal liver metastasis with coexisting IgG4-rich inflammatory pseudotumor-like changes: a case report.
A 71-year-old man developed hepatic lesions in segments S5 and S7, diagnosed on imaging as colorectal liver metastases, eight months after surgery for rectal cancer.
A case of small pancreatic neuroendocrine tumor of less than 10 mm showing metastasis to multiple organs.
A woman in her sixties followed for a pancreatic body cyst for more than a decade developed a hypoechoic pancreatic lesion.
Reduced Length of ADT and ARTA With XRT in High-Risk Prostate Cancer (RELAX): A Randomised Controlled Trial.
The RELAX trial is a multicenter, phase II randomized controlled trial evaluating a short regimen of androgen deprivation therapy (ADT) and androgen receptor-targeted agent (ARTA) combined with external beam…
ESTRO recommendations for the use, planning and delivery of reirradiation in locally recurrent rectal cancer - Endorsed by ASTRO.
This systematic review and practice guideline by ESTRO, endorsed by ASTRO, addresses reirradiation in locally recurrent rectal cancer (LRRC).
Robotic Resection of Right Perihilar Intrahepatic Cholangiocarcinoma: Practical Technique of Major Hepatic Resection for Biliary Tract Cancer.
A 76-year-old woman with hepatic steatosis had a 5.5-cm centrally located intrahepatic cholangiocarcinoma near the hilum. Imaging and volumetric assessment were used to evaluate the future liver remnant.
Any impact of pre-operative radiotherapy on renal function in retroperitoneal soft tissue sarcomas? A secondary ancillary analysis of the EORTC 62092 STRASS 1 trial.
This ancillary analysis of the EORTC 62092 STRASS 1 trial evaluated the impact of preoperative radiotherapy on renal function in patients with retroperitoneal soft tissue sarcomas.
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