Trending archive
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542 articles
September 202624
Associations Between Gut Microbiota and Immune Profiles in Community-Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum.
This randomized controlled trial investigated the effects of Polygonatum odoratum on gut microbiota and immune profiles in 140 community-dwelling older adults aged 60 and above over 90 days.
Bridging the gap in caregiver support: A systematic review of screening practices in primary care.
This systematic review examined the use of caregiver burden screening practices in primary care, focusing on studies from 2013 to 2023.
Awake full-endoscopic transforaminal lumbar interbody fusion via the trans-Kambin approach under local anaesthesia in a nonagenarian.
A nonagenarian with recurrent symptomatic foraminal stenosis at L4-L5, following previous decompression surgeries, underwent full-endoscopic transforaminal lumbar interbody fusion (FE-TLIF) via the trans-Kambin approach…
Survival benefit of guideline-directed medical therapy in older patients with heart failure: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the survival benefits of guideline-directed medical therapy (GDMT) in older patients (≥65 years) with heart failure and reduced ejection fraction (HFrEF).
Brain-motor behavior coupling during walking while negotiating obstacle: A systematic review.
This systematic review examined cortical activity alongside gait during obstacle negotiation in adults, using a brain–motor behavior framework.
Alzheimer's disease and related dementias in South and Southeast Asia: a systematic review and meta-analysis of epidemiology and associated factors.
This systematic review and meta-analysis examined the prevalence and associated factors of Alzheimer's disease and related dementias (AD/ADRDs) in South and Southeast Asia, analyzing data from 31 studies.
Cancer co-medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care.
This multicentre, single-blinded randomised controlled trial tested a pharmacist-led medication review using the FORTA list versus usual care in patients aged ≥ 65 years with common cancers and polypharmacy at ten…
Systematic review of cost-effectiveness analyses of weight loss interventions for knee osteoarthritis.
This systematic review assessed the cost-effectiveness of weight-loss interventions for adults with knee osteoarthritis and obesity.
Implementing the MATILDA intervention to enhance community participation for older adults with intellectual disability: A feasibility randomised controlled trial and RE-AIM guided process evaluation.
This feasibility randomized controlled trial evaluated the MATILDA intervention aimed at enhancing community participation among older adults with intellectual disabilities in the UK.
Artificial Intelligence and Machine Learning for Outcome Prediction After Osteoporotic Hip Fracture: A Systematic Review and Meta-analysis of Prediction Model Performance.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) and machine learning (ML) models in predicting outcomes after osteoporotic hip fractures.
Total Intravenous vs Volatile Inhalational Anesthesia for Major Noncardiac Surgery: A Randomized Clinical Trial.
This randomized clinical trial compared total intravenous anesthesia (TIVA) with volatile inhalational anesthesia in 2508 older adults (aged 50+) undergoing major noncardiac surgery.
Effects of a self-selected vegetarian compared with an omnivorous diet on protein intake and muscle mass in older adults during resistance exercise: the IMPACT randomized controlled trial.
The IMPACT randomized noninferiority trial compared self-selected lacto-ovo vegetarian and omnivorous diets during 12 weeks of resistance training in adults aged 55 years and older.
A Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay-Based Diet with or without Digital Cognitive Training Improves Cognitive Function and Nutritional Status in Older Adults with Mild Cognitive Impairment.
This 12-week, open-label cluster-randomized controlled trial evaluated a MIND-based diet, with or without digital cognitive training, in 80 adults aged 65 years or older with mild cognitive impairment attending daycare…
Multifactorial and multiple component interventions for preventing falls in older people living in the community.
This systematic review and meta-analysis evaluated the effects of multifactorial and multiple component fall prevention interventions in community-dwelling older adults (≥ 60 years).
Barriers and enablers to deprescribing from the perspectives of older adults with polypharmacy and their stakeholders: A systematic review of qualitative studies.
This systematic review synthesised qualitative studies on barriers and enablers to deprescribing among older adults with polypharmacy and relevant stakeholders.
Comparative effects of activity-based interventions on quality of life among community-dwelling older adults: A systematic review and Bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis examined activity-based interventions and quality of life (QoL) in community-dwelling older adults aged 65 years or older.
Effectiveness of Nutrition and Exercise Interventions Among Community-Dwelling Older Vietnamese Adults with Sarcopenia: A Cluster-Randomized Controlled Trial.
This cluster-randomized controlled trial evaluated the effectiveness of exercise alone and exercise with nutritional support in managing sarcopenia among 90 older Vietnamese adults aged 60-70.
Haloperidol for Hypoactive and Hyperactive Delirium in ICU Patients-A Post Hoc Bayesian Analysis of the AID-ICU Trial.
This post hoc analysis of the AID-ICU trial evaluated the effects of haloperidol on delirium subtypes in 987 ICU patients. Haloperidol was linked to more days alive out of hospital, with a 76.5% probability of greater…
"A better system" - managing the adverse effects of prescribed medicines: Cluster-randomised controlled trial and process evaluation of the ADRe Profile in primary care.
This cluster-randomized controlled trial evaluated the ADRe Profile's effectiveness in managing adverse drug reactions among patients aged ≥65 on multiple long-term medications in primary care.
Using the Social Ecological Model to identify barriers to accessing and using primary healthcare services by the rural Bangladeshi elderly: A systematic review.
This systematic review examined barriers to accessing primary healthcare services among rural elderly populations in Bangladesh, utilizing the Social Ecological Model.
Associations Between Peripheral Blood Inflammatory and Immune Markers and Osteoporotic and Fragility Fractures: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the associations between peripheral blood inflammatory and immune markers and osteoporotic or fragility fractures.
Risk factors for frailty in older adults with cancer: a systematic review.
This systematic review examined risk factors for frailty in older adults with cancer, integrating data from 30 studies. It identified six categories of influencing factors: disease-related, physiological, psychological…
Examining the Effects of Testosterone and Strength Training on Fat Mass and Functional Strength in Older Adult Males: A Systematic Review.
This systematic review evaluated the effects of testosterone therapy combined with strength training versus strength training alone in males over 60.
Impact of Dietetic Counseling Combined With Digital Tools on Obesity-Related Indices in Greek Adults: The GATEKEEPER Study.
The GATEKEEPER study evaluated the impact of dietetic counseling combined with digital tools on obesity-related outcomes in adults aged 55 and older at high risk for metabolic syndrome.
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