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937 articles
October 202624
SYSTEMATIC REVIEW AND BRAZILIAN EXPERT CONSENSUS ON THE USE OF BIOSIMILARS IN INFLAMMATORY BOWEL DISEASE: BRAZILIAN ORGANIZATION FOR CROHN'S AND COLITIS.
This systematic review and Brazilian expert consensus assessed biosimilar use in inflammatory bowel disease (IBD), addressing clinical, therapeutic, and economic questions.
Impact of Side-to-Side Versus End-to-Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreatoduodenectomy (IPAD study): A Randomized Controlled Trial.
The IPAD study was a prospective, open-label randomized trial at two high-volume pancreatic centers in France, comparing side-to-side with end-to-side gastrojejunostomy in adults undergoing pancreatoduodenectomy for…
Depot-specific molecular remodelling of human adipose tissue and liver following bariatric surgery revealed by longitudinal multi-omic profiling.
This randomised, prospective, longitudinal study followed women living with obesity for 1 year during a low-calorie diet followed by sleeve gastrectomy or Roux-en-Y gastric bypass, with a non-obese control group.
Endoscopic double-layer nylon rope ligation for rescue of gastric ulcer bleeding after failed OTSC treatment: A case report (with video).
A 61-year-old man presented with hematemesis and melena due to a bleeding gastric ulcer classified as Forrest IIa. After initial treatment with an over-the-scope clip (OTSC) failed, he underwent endoscopic double-layer…
Safety profile of elafibranor versus placebo in primary biliary cholangitis: A systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the safety profile of elafibranor compared to placebo in patients with primary biliary cholangitis (PBC) who did not adequately respond to first-line therapy.
Genetic evidence for associations between gastroesophageal reflux disease and site-specific extraesophageal cancers: A Mendelian randomization study.
This Mendelian randomization study investigated the relationship between genetically predicted gastroesophageal reflux disease (GERD) and 22 extraesophageal cancers using data from over 600,000 individuals.
Cholecystogastric fistula masquerading as gastrointestinal stromal tumour: Unusual presentation of gallbladder adenomyomatosis - a case report.
A 71-year-old woman presented with acute abdominal pain and signs of mechanical small-bowel obstruction. Imaging revealed a 6-cm mass near the gastric antrum, initially suspected to be an invasive gastrointestinal…
Thyrotoxicosis-Associated Cholestatic Jaundice in a Patient With Incidental Gallstone Disease: A Case Report and Literature Review.
A 62-year-old woman presented with right upper quadrant pain, weight loss, and jaundice. Laboratory tests indicated cholestatic liver injury, and imaging revealed a solitary gallstone and signs of right-sided heart…
Tumor-Free Circulating Tumor DNA in Node-Negative Rectal Cancers Undergoing Neoadjuvant Chemotherapy, Excision, and Observation in the Phase II NEO Trial (CO.28).
The Phase II NEO trial investigated the role of circulating tumor DNA (ctDNA) in guiding treatment decisions for 53 patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy and transanal excision.
Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.
This meta-analysis compared early and standard liver transplantation in patients with alcohol-related liver disease. It included 12 studies and 2323 patients.
Markedly Elevated CA 19-9 in Type I Mirizzi Syndrome in the Absence of Malignancy: A Case Report.
A 50-year-old man presented with acute obstructive jaundice, fever, and right upper quadrant pain; serum CA 19-9 was 1000 U/mL.
Effect of a walnut-based low carbohydrate diet on fat redistribution and visceral fat accumulation in people with central obesity: A randomized controlled trial.
This randomized controlled trial investigated the effects of a walnut-based low carbohydrate diet (w-LCD) on fat redistribution and visceral fat accumulation in individuals with central obesity over 12 weeks.
Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).
The missing evidence: Stricturing Crohn's disease in clinical trials, a systematic review.
This systematic review assessed the efficacy of biologic and small-molecule therapies in stricturing Crohn's disease (CD) among adults.
Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).
Well-differentiated SMARCB1-deficient Pancreatic Malignancy With Indolent Liver Metastases.
A 66-year-old woman underwent distal pancreatectomy for a pancreatic tail malignancy, later developing liver metastases six years post-surgery.
Gastric neuroendocrine tumours after prolonged proton pump inhibitor use.
A woman in her 40s with chronic gastro-oesophageal reflux disease had been on proton pump inhibitors for 20 years. She was diagnosed with gastric neuroendocrine tumours during an upper endoscopy.
Tuberculosis and persistent chylous ascites.
A late adolescent boy presented with fever, weight loss, and lymphadenopathy, leading to a diagnosis of extrapulmonary tuberculosis.
Negative affect influences the computations underlying food choice in bulimia nervosa.
This randomized controlled trial examined how negative affect influences food choice dynamics in 25 women with bulimia nervosa (BN) and 21 healthy controls.
A Phase I Study of PF-07062119, an Anti-GUCY2C/Anti-CD3 Bispecific Fc Antibody, in Patients with Advanced Gastrointestinal Cancers.
This Phase I multicenter study evaluated PF-07062119, an anti-GUCY2C/anti-CD3 bispecific antibody, in 79 patients with advanced gastrointestinal cancers.
Opioid-Sparing Analgesia After Laparoscopic Gastrectomy: Exploratory Clinical Outcomes and Cine-MRI Assessment of Small-Bowel Motility.
This randomized controlled trial evaluated opioid-sparing multimodal analgesia versus conventional opioid analgesia in 130 patients undergoing laparoscopic radical gastrectomy.
Lenalidomide-Related Diarrhea in Patients with Multiple Myeloma Is Associated with Gut Microbiota Dysbiosis and Disruption of the Bile Acid Pool.
This Phase II randomized controlled trial investigated the relationship between gut microbiota dysbiosis, bile acid pool disruption, and lenalidomide-related diarrhea (LRD) in patients with multiple myeloma.
Balloon Enteroscopy-Assisted ERCP and EUS-Guided Biliary Drainage for Malignant Biliary Obstruction in Patients With Surgically Altered Anatomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed balloon enteroscopy-assisted ERCP (BEA-ERCP) versus EUS-guided biliary drainage (EUS-BD) for malignant biliary obstruction in patients with surgically altered anatomy.
A novel variant of pancreaticobiliary maljunction: Complete opening of the common bile duct into the duct of Santorini in a patient with pancreas divisum.
A 20-year-old woman with recurrent cholestasis and acute pancreatitis presented with fever, jaundice, and abdominal pain; laboratory findings supported cholangitis and pancreatitis.
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