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1382 articles

September 20254

Clinical ResearchDermatology

Efficacy and safety of benvitimod 1% cream for atopic dermatitis in patients aged 2 years and older: A phase III randomized clinical trial.

This phase III randomized controlled trial compared benvitimod 1% cream with vehicle in 271 Chinese patients aged 2 years or older with atopic dermatitis. Participants applied treatment twice daily for 8 weeks.

Chin Med J (Engl)Sep 16, 2025Read summary
Case ReportNephrologyOpen access

Membranous-like glomerulopathy with masked IgG-k deposits in a pediatric patient with juvenile idiopathic arthritis.

A 12-year-old girl with systemic juvenile idiopathic arthritis had persistent proteinuria despite normal kidney function. Her first kidney biopsy suggested mild C3 glomerulonephritis.

Pediatr NephrolSep 15, 2025Read case
Case ReportNeurosurgery

Papillary Tumors of the Pineal Region (PTPR) in Pediatric Population: A Case Report and Literature Review.

A 3-year-old child was diagnosed with a papillary tumor of the pineal region and underwent subtotal resection. Adjuvant radiotherapy was followed by long-term disease stability: no tumor progression was reported during…

Asia Pac J Clin OncolSep 3, 2025Read case
Clinical ResearchPreventive Medicine / Public Health

Examining Racial Differences in the Effects of the Brazilian State-Level Police Substance Use Prevention Program in Schools: a Cluster-Randomized Controlled Trial.

This analysis of two cluster-randomized controlled trials conducted in 2019 examined whether the PROERD school-based substance-use prevention program had different effects across racial groups.

J Racial Ethn Health DisparitiesSep 2, 2025Read summary

August 20255

Clinical ResearchPediatrics

Risk mitigation strategies for children and young people admitted with mental health crisis to acute paediatric care: A systematic review with narrative synthesis.

This systematic review with narrative synthesis examined evaluated pathways for managing self-harm and suicidality risk among children and young people admitted to acute hospital settings during a mental health crisis.

J Child Health CareAug 29, 2025Read summary
Clinical ResearchPediatrics

A Meta-Analytic Review of Spelling Interventions for Students With or At-Risk for Learning Disabilities.

This meta-analysis reviewed spelling interventions evaluated in randomized controlled trials, quasi-experimental studies, and single-case designs among 2,229 students in Grades K–9, the vast majority with or at risk for…

J Learn DisabilAug 28, 2025Read summary
Clinical ResearchPediatrics

The impact of early powered mobility training in families and children with Spinal Muscular Atrophy Type I.

This randomized, waitlist-controlled, single-blinded trial in Spain evaluated 12 weeks of powered mobility training with modified ride-on toy cars in 16 children aged 10 months to 5 years with spinal muscular atrophy…

Assist TechnolAug 22, 2025Read summary
Clinical ResearchPediatrics

Persistent Pulmonary Hypertension Among Infants Undergoing Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether therapeutic hypothermia (TH), compared with no TH or usual care, was associated with persistent pulmonary hypertension (PPHN) in infants with moderate to severe…

Ther Hypothermia Temp ManagAug 20, 2025Read summary
Clinical ResearchPsychiatry

Outcomes of Experiencing Interpersonal Violence in Autism: A Mixed Methods Systematic Review and Meta-Analysis.

This mixed-methods systematic review and meta-analysis examined outcomes of interpersonal violence among autistic people and gender-related differences.

Trauma Violence AbuseAug 9, 2025Read summary

July 20252

June 20255

Clinical ResearchPsychiatryOpen access

Auditory Global-Local Processing in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined auditory global-local pitch processing in individuals with autism spectrum disorder (ASD) compared with typically developing peers.

J Autism Dev DisordJun 24, 2025Read summary
Clinical ResearchPediatricsOpen access

Project ImPACT Reduces Social Hyporesponsiveness and Translates to More Optimal Expressive Language Outcomes in Some Infants at Increased Likelihood of Autism.

This randomized controlled trial tested whether Project ImPACT, a caregiver-implemented naturalistic developmental behavioral intervention, could improve later expressive language in infant siblings of autistic children…

J Autism Dev DisordJun 23, 2025Read summary
Clinical ResearchPediatricsOpen access

Treating preschooler behavioural sleep problems via parent-mediated telehealth: A randomized controlled trial.

This randomized controlled trial evaluated a parent-mediated behavioural sleep intervention delivered through three fortnightly 90-minute videoconference sessions for children aged 3–5 years.

Br J Clin PsycholJun 19, 2025Read summary
Clinical ResearchPediatricsOpen access

Effects of Rhythmic Motor and Behavioral Intervention on Motor and Social Performance in Preschool Children with Autism Spectrum Disorder: A Pilot Randomized Controlled Study.

This pilot randomized controlled study evaluated an 8-week Rhythmic Motor and Behavioral Intervention (RMBI) in 30 preschool children with autism spectrum disorder (median age 5.8 years; 20 males).

J Autism Dev DisordJun 11, 2025Read summary
Clinical ResearchPediatricsOpen access

Randomized Controlled Trial of Developmental Reciprocity Treatment in Young Children with Autism.

This randomized controlled 24-week pilot trial compared Developmental Reciprocity Treatment, combining parent training and direct child treatment, with delayed treatment in 37 children aged 2–5 years with autism…

J Autism Dev DisordJun 9, 2025Read summary

May 20257

Case ReportMedical Genetics

A Rare Presentation of HIST1H1E Syndrome with Short Stature and Multiple Pituitary Hormone Deficiencies.

A 17-year-old male was evaluated for short stature and had characteristic facial features and neurodevelopmental delay. Genetic testing identified a heterozygous pathogenic H1-4 variant on chromosome 6p22.2, confirming…

J Clin Res Pediatr EndocrinolMay 30, 2025Read case
Clinical ResearchPediatricsOpen access

Cannabidiol (CBD) Treatment for Severe Problem Behaviors in Autistic Boys: A Randomized Clinical Trial.

This double-blind, placebo-controlled crossover trial assessed plant-derived cannabidiol (CBD) in autistic boys aged 7–14 years with severe behavior problems.

J Autism Dev DisordMay 24, 2025Read summary
Clinical ResearchPediatricsOpen access

The Effects of Dialogic Reading Intervention on Verbal Interaction and Engagement in Young Autistic Children: A Randomized Controlled Preliminary Study.

This preliminary randomized controlled trial compared dialogic reading with standard book reading in 14 young children with autism.

J Autism Dev DisordMay 22, 2025Read summary
Clinical ResearchPediatricsOpen access

The Effects of Robots on Children with Autism Spectrum Disorder: A Meta-analysis.

This meta-analysis assessed robotic interventions intended to support development in children with autism spectrum disorder (ASD).

J Autism Dev DisordMay 21, 2025Read summary
Clinical ResearchPsychiatryOpen access

Mixed Methods Findings from a Stepped Wedge Hybrid Implementation Trial of ATTAIN NAV: A Mental Health Family Navigation Intervention for Autistic Youth.

This mixed-methods, stepped-wedge hybrid implementation trial evaluated ATTAIN NAV, a family-navigation intervention intended to improve mental health service access and engagement for school-age autistic youth.

J Autism Dev DisordMay 8, 2025Read summary
Clinical ResearchPsychiatryOpen access

Social Responsiveness as a Mediator in Adapted Cognitive Behavioral Therapy for Autistic Youth with Maladaptive and Interfering Anxiety.

This secondary mediation analysis of a multisite randomized clinical trial examined whether improved social responsiveness helped explain outcomes with adapted cognitive behavioral therapy (BIACA) in autistic youth aged…

J Autism Dev DisordMay 7, 2025Read summary
Clinical ResearchPediatricsOpen access

Examining Behavioral Interventions for Infancy and Early Toddlerhood: A Systematic Review of Intervention Effects, Parameters, and Participants.

This systematic review examined behavioral interventions based on operant learning for children in the first two years of life, focusing on key developmental areas.

J Autism Dev DisordMay 5, 2025Read summary

April 20251

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