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1357 articles
October 202624
Clinical Efficacy of 5-Aminolevulinic Acid Photodynamic Therapy Combined With Interferon Spray in Treating Common and Plantar Warts.
This randomized controlled trial evaluated the efficacy of 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) combined with recombinant human interferon alpha 2b (rhIFN-α2b) spray in 104 patients with refractory…
Artificial intelligence chatbot-assisted preoperative education and perioperative anxiety in surgical patients: A systematic review and structured narrative synthesis of randomized controlled trials.
This systematic review and structured narrative synthesis assessed whether AI chatbot-assisted preoperative education affects perioperative anxiety in surgical patients.
Janus kinase inhibitors in the management of lichen planus: a systematic review.
Lichen planus (LP) is a chronic, lymphocytic, inflammatory skin disorder that can affect the skin, hair follicles, nails, and mucous membranes. It has limited treatment options.
Effect of preoperative video-based digital educational program on incidence of delirium and length of hospital stay following coronary artery bypass grafting: A randomized controlled trial.
This parallel-group randomized controlled trial evaluated whether adding an 8-minute Arabic video-based educational program to standard preoperative education affected delirium and hospital stay after elective…
The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.
Regularly Scheduled Acetaminophen for Pain in Long-Term Care: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed whether regularly scheduled acetaminophen improves pain in long-term care residents.
Effectiveness of psychosocial interventions addressing informal caregivers' mental health: an umbrella systematic review with 26,481 participants.
This umbrella systematic review and random-effects meta-analysis assessed psychosocial interventions for the mental health of informal caregivers, grouped by care recipients’ clinical conditions.
Synbiotic supplementation leads to gut microbiome communities with functional capacity linked to better brain white matter development in preterm infants.
This secondary analysis of a randomized controlled trial examined whether daily synbiotic and nutritional supplementation could shape gut microbiome function in very and extremely preterm infants, and how those…
Neoadjuvant niraparib monotherapy for unresectable, homologous recombination deficiency-positive, high-grade serous ovarian cancer (NANT): a multicentre, single-arm, phase 2 trial.
This multicentre, single-arm phase 2 trial evaluated two cycles of neoadjuvant niraparib monotherapy in treatment-naïve patients with HRD-positive, advanced high-grade serous or endometrioid ovarian cancer considered…
Challenging historical associations and reassuring women: an updated meta-analysis of multiple sclerosis relapse risk following assisted reproductive technology.
This systematic review and random-effects meta-analysis examined whether assisted reproductive technology (ART) is associated with multiple sclerosis (MS) relapses in women with MS or incident MS in previously healthy…
Immunogenicity and Safety of Co-administration of Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine With 20-Valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years: A Randomized, Non-inferiority Trial.
This phase III, open-label, randomized non-inferiority trial compared concomitant versus one-month-apart administration of adjuvanted RSV prefusion F protein vaccine (RSVPreF3) and 20-valent pneumococcal conjugate…
Fractal radiomics as a virtual biopsy in glioma: A systematic review and meta-analysis of molecular status, radiogenomic associations, and survival outcomes.
This systematic review and meta-analysis assessed whether fractal-based imaging features can predict molecular alterations and outcomes in glioma.
A Phase 1/2 Dose-Ranging Safety and Immunogenicity Study of mRNA-Based Candidate Pandemic Influenza Vaccines in Healthy Adults.
This randomised phase 1/2 dose-ranging study evaluated the safety, reactogenicity, and immunogenicity of mRNA-1018 pandemic influenza vaccine candidates in healthy adults.
Immunogenicity and Safety of the Adjuvanted Respiratory Syncytial Virus Prefusion F Protein-Based Vaccine When Co-administered With the Adjuvanted Recombinant Herpes Zoster Subunit Vaccine in Adults ≥ 50 Years of Age.
This phase III, open-label, randomised trial compared co-administration of adjuvanted RSVPreF3 and recombinant zoster vaccine (RZV) with administration one month apart in adults aged ≥50 years.
MRI-derived radiomics for prostate cancer active surveillance: a systematic review.
This PRISMA 2020 systematic review assessed MRI-derived radiomic and artificial intelligence models for selecting men with prostate cancer for active surveillance, detecting clinically significant cancer at baseline…
Peripheral microbial metabolites as indicators of gut microbiome disruption: systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether circulating microbial metabolites can indicate gut microbiome disruption.
Targeted Muscle Reinnervation Versus Regenerative Peripheral Nerve Interface: A Systematic Review Comparing Postoperative Complications and Operative Time.
This systematic review compared postoperative surgical complications and operative time for targeted muscle reinnervation (TMR) and regenerative peripheral nerve interface (RPNI) after upper- or lower-extremity…
Lithium during maintenance electroconvulsive therapy: Secondary neuropsychological outcomes from the open-label PRASED randomized controlled trial.
This secondary neuropsychological analysis of the multicenter, open-label PRASED randomized controlled trial examined patients with major depressive disorder who had remitted after acute electroconvulsive therapy (ECT).
Left Atrial Appendage Closure Versus Oral Anticoagulation in Atrial Fibrillation: An Updated Meta-Analysis of RCTs Using Reconstructed Individual Patient Data.
This updated meta-analysis combined reconstructed individual patient data from six randomized controlled trials comparing left atrial appendage closure (LAAC) with oral anticoagulation (OAC) in 7,004 patients with…
Metabolic Bariatric Surgery for Cancer Prevention and Risk Reduction in Patients with Obesity: A GRADE-Based International Federation for the Surgery and Other Therapies for Obesity (IFSO) Position Statement.
This GRADE-based international position statement systematically reviewed evidence on metabolic bariatric surgery (MBS) and cancer incidence in adults with obesity, comparing surgery with non-surgical weight-loss…
Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) models in classifying glomerular diseases using pathology images.
Maternal circulating cytokine and chemokine levels during pregnancy and risk of autism spectrum disorder in offspring: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether maternal blood cytokine and chemokine levels during pregnancy were associated with autism in offspring, drawing on seven human observational studies.
Exercise to enhance antipsychotic effectiveness and mitigate metabolic harm: systematic review and meta-analysis.
This systematic review and meta-analysis pooled randomised controlled trials of supervised exercise in adults receiving antipsychotic medication for psychotic disorders.
Brief social contact videos to promote treatment seeking among young adults with depressive symptoms: Intention change, suicidal ideation, and treatment use in a randomized controlled trial.
This randomized controlled trial tested whether brief social contact videos featuring personal recovery stories increased help-seeking and treatment use among 1,545 young adults aged 18–25 years with depressive…
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