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2000 articles
July 202624
Multifocal Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor Mimicking Posttransplant Lymphoproliferative Disorder in a Renal Allograft Recipient.
A 19-year-old renal transplant recipient presented with abdominal symptoms suggestive of posttransplant lymphoproliferative disorder (PTLD). Imaging with 18F-FDG PET/CT revealed multiple hypermetabolic liver lesions.
Cardiotoxicity of newer HER2-Directed therapies in breast cancer: A systematic review and meta-analysis of incidence and comparative risk.
This systematic review and meta-analysis evaluated the incidence and comparative risk of cardiotoxicity associated with newer HER2-targeted therapies versus trastuzumab-based regimens in 35,984 patients.
[ 18 F]FDG PET/MRI for axillary staging in node positive breast cancer patients receiving primary systemic therapy. A prospective single arm trial.
[18F]FDG PET/MRI was evaluated for axillary staging in node-positive breast cancer patients undergoing primary systemic therapy in a prospective single-arm trial.
ADT Combinations With Radiation for Prostate Cancer: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the impact of first-generation nonsteroidal antiandrogens (NSAA) on overall survival (OS) and toxicity in patients with localized prostate cancer receiving androgen…
Minimal incision-assisted endoscopic versus conventional open breast-conserving surgery: A multicentre randomized clinical trial.
This phase III multicentre randomized controlled trial compared minimal incision-assisted endoscopic breast-conserving surgery (M-E-BCS) with conventional open breast-conserving surgery (C-O-BCS) in early-stage breast…
The application of artificial intelligence in healthcare practice: A mapping review of systematic reviews.
This systematic review mapped 368 systematic reviews on artificial intelligence (AI) applications in healthcare, published from 2019 to February 2026.
Acupuncture vs. Massage for Insomnia and Pain in Advanced Cancer: Exploratory RCT.
This multicenter randomized controlled trial compared acupuncture and massage therapy for treating insomnia in 234 patients with advanced cancer and baseline insomnia.
Lutetium-177-PSMA radioligand therapy in metastatic hormone-sensitive prostate cancer: A systematic review of efficacy, safety, and combination strategies.
This systematic review evaluates the efficacy and safety of Lutetium-177-PSMA radioligand therapy (¹⁷⁷Lu-PSMA-RLT) in metastatic hormone-sensitive prostate cancer (mHSPC).
Assessment of the risk of developing second tumors after pediatric craniospinal irradiation.
This systematic review assessed the risk of second tumors following pediatric craniospinal irradiation, comparing Three-Dimensional Conformal Radiotherapy (3DCRT) and Volumetric Modulated Arc Therapy (VMAT).
Anaplastic Thyroid Carcinoma With Kinase Gene Fusions: Report of 3 Cases With Corresponding Cytologic, Histologic, and Molecular Findings.
Three cases of anaplastic thyroid carcinoma (ATC) with kinase gene fusions were analyzed, revealing typical cytologic features such as marked nuclear atypia and sarcomatoid morphology.
OPTIM: a randomized phase II trial of nivolumab followed by nivolumab-ipilimumab or docetaxel at progression in recurrent/metastatic squamous cell carcinoma of the head and neck (OPTIM; AIO-KHT-0117).
OPTIM was a randomized phase II trial in adults with platinum-refractory recurrent or metastatic squamous cell carcinoma of the head and neck.
Survival Outcomes of Head and Neck Neuroendocrine Carcinoma: A Systematic Review.
This systematic review examined survival outcomes in patients with head and neck neuroendocrine carcinoma (HNNEC), focusing on tumor characteristics and treatment strategies.
Splenic Granulomatous Lesions Mimicking Metastases on 18 F-FDG PET/CT in a Patient With Ovarian Cancer.
A 76-year-old woman with a history of ovarian cancer underwent 18 F-FDG PET/CT due to increased CA199 levels in routine surveillance.
Comparison of obecabtagene autoleucel versus an external control arm in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia.
The FELIX study evaluated the efficacy of obecabtagene autoleucel (obe-cel) in adults with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) compared to historical controls.
Evaluating the diagnostic performance of exosome biomarkers for the detection of ovarian cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of exosome biomarkers for ovarian cancer detection, analyzing 16 studies.
Anticancer, hepatoprotective, and mechanistic evidence of chlorogenic acid in liver cancer: A systematic review.
This systematic review evaluated the effects of chlorogenic acid (CGA) on liver cancer, analyzing 21 studies. CGA showed anticancer effects in preclinical models by inhibiting tumor cell proliferation and inducing…
Disease Stabilization with MEK Inhibitors in NF1-Associated Plexiform Neurofibromas: A Systematic Review and Meta-Analysis with Subgroup Analyses by Age and Study Design.
This systematic review and meta-analysis evaluated the efficacy and safety of MEK inhibitors in 769 patients with NF1-associated plexiform neurofibromas (PN).
Immune checkpoint inhibitors in people living with HIV and cancer: a Kaplan-Meier-derived individual patient data meta-analysis.
This systematic review and meta-analysis assessed immune checkpoint inhibitor (ICI) efficacy and safety in people living with HIV (PLWH) and cancer, compared with people without HIV.
A Phase 2 Trial of Intravesical Cabazitaxel, Gemcitabine, and Cisplatin for the Treatment of Nonmuscle-Invasive Bacillus Calmette-Guérin-Unresponsive Urothelial Carcinoma of the Bladder.
This single-center phase 2 trial evaluated sequential intravesical cabazitaxel, gemcitabine, and cisplatin in patients with BCG-unresponsive high-risk nonmuscle-invasive bladder cancer who refused or were ineligible for…
Recurrent Metastatic Esthesioneuroblastoma: First-in-human α/β PRRT With Actinium-225/Lutetium-177-DOTA-LM3 SSTR Antagonist Achieving Partial Response After Failure of Lutetium-177-DOTATOC PRRT.
A 45-year-old woman with recurrent metastatic esthesioneuroblastoma, previously treated and symptomatic, received a novel peptide receptor radionuclide therapy (PRRT) using a somatostatin receptor antagonist labeled…
The laryngofissure approach for near-infrared photoimmunotherapy in laryngeal cancer: A novel larynx-preservation strategy.
A 67-year-old male with laryngeal cancer presented with hoarseness and was staged as cT2N2bM0, Stage IVA. After two years of concurrent chemoradiotherapy, he experienced local recurrence in the subglottic and posterior…
Integrated Evaluation of Survival, Surgical Conversion, and Toxicity for Induction Therapy in Initially Unresectable Colorectal Liver Metastases: An Individual Patient Data Network Meta-analysis.
This network meta-analysis evaluated the efficacy of induction therapies for initially unresectable colorectal cancer liver metastases (CRLM) using individual patient data from seven randomized controlled trials…
Impact of palliative intervention on end-of-life outcomes for patients undergoing surgery for cancer.
This randomized controlled trial examined the impact of early palliative care on end-of-life outcomes in 235 patients undergoing curative surgery for abdominal cancer.
Artificial intelligence-assisted detection and optical differentiation of colorectal lesions in Lynch syndrome surveillance (CADLY2): a multicentre, open-label, randomised controlled superiority trial.
The CADLY2 trial evaluated the impact of computer-aided detection (CADe) on adenoma detection rates during surveillance colonoscopy in patients with Lynch syndrome.
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