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2000 articles
July 202624
Total Neoadjuvant Therapy With Long-Course Radiotherapy Versus Chemoradiotherapy in High-Risk Locally Advanced Rectal Cancer (TNTCRT): A Multicenter, Randomized, Phase III Trial.
This multicenter, randomized, phase III trial evaluated total neoadjuvant therapy (TNT) with long-course radiotherapy (LCRT) versus conventional neoadjuvant chemoradiotherapy (nCRT) in patients with high-risk locally…
First Pediatric Use of Pegulicianine for Fluorescence-Guided Surgery in Li-Fraumeni-Associated Rhabdomyosarcoma.
A 4-year-old boy with Li-Fraumeni syndrome and a TP53 mutation presented with a supraclavicular mass, diagnosed as embryonal rhabdomyosarcoma with anaplastic features and positive margins.
Association Between Dinutuximab Beta Exposure and Post-End-of-Treatment Survival in Neuroblastoma: A Weighted Patient-Level Analysis of Three Clinical Studies.
This systematic review analyzed the association between dinutuximab beta (DB) exposure and post-end-of-treatment survival in neuroblastoma patients using data from three clinical trials.
Prospective comparison of [ 68 Ga]Ga-FAPI-04 PET/MRI, [ 18 F]FDG PET/CT, and contrast-enhanced MRI for predicting pathologic complete response after neoadjuvant chemotherapy in breast cancer.
This prospective single-center study evaluated the effectiveness of [68Ga]Ga-FAPI-04 PET/MRI, [18F]FDG PET/CT, and contrast-enhanced MRI in predicting pathologic complete response (pCR) after neoadjuvant chemotherapy in…
Hemophagocytic lymphohistiocytosis and posterior reversible encephalopathy syndrome during BRAF/MEK inhibitor therapy following immune checkpoint blockade in metastatic melanoma: a case report.
A 61-year-old female with BRAF V600K-mutant metastatic melanoma developed hemophagocytic lymphohistiocytosis (HLH) after sequential treatment with immune checkpoint inhibitors and BRAF/MEK inhibitors.
Immune checkpoint inhibitor-based chemotherapy for granulocyte-colony stimulating factor-producing advanced esophageal squamous cell carcinoma: a report of three cases.
Three men with advanced granulocyte-colony stimulating factor (G-CSF)-producing esophageal squamous cell carcinoma received fluorouracil, cisplatin, and pembrolizumab.
Novel Germline ELP1 Splice-Acceptor Variant in NF1-Negative Optic Pathway Glioma: Expanding the Clinical Spectrum Associated With ELP1 Variation.
A 7-year-old boy presented with an optic pathway glioma without neurofibromatosis type 1 (NF1). Whole-exome sequencing revealed a novel germline ELP1 splice-acceptor variant, classified as likely pathogenic.
Fludarabine, Busulfan, Thiotepa, and Melphalan: A Novel Low-Toxicity Myeloablative Conditioning Regimen for Haploidentical HSCT in Children and Adolescents Aged ≥7 Years With Transfusion-Dependent β-Thalassemia.
This prospective clinical trial evaluated a novel low-toxicity myeloablative conditioning regimen (F-BMT) in 29 children and adolescents aged ≥7 years with transfusion-dependent β-thalassemia undergoing haploidentical…
More Prominent 18 F-FDG Uptake Than 68 Ga-FAPI-04 in Nongestational Choriocarcinoma.
A 56-year-old man was found to have nongestational choriocarcinoma of unknown primary with multiple metastases. On PET/CT, the lesions showed intense 18F-FDG uptake but limited accumulation of 68Ga-FAPI-04.
Incidental Detection of Ovarian Hyperstimulation on FDG PET/CT After Oocyte Retrieval in a Breast Cancer Patient.
A breast cancer patient undergoing fertility preservation presented for staging with FDG PET/CT, which incidentally revealed bilateral polycystic ovarian enlargement with intense FDG uptake.
Breast implant-associated squamous cell carcinoma (BIA-SCC): Clinicopathologic analysis of two cases with radiologic-pathologic correlation and a review of the literature.
This report details two cases of breast implant-associated squamous cell carcinoma (BIA-SCC) in women in their 50s, presenting with breast pain and swelling one to two decades post-implantation.
Minimally invasive versus open surgery for gallbladder cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the post-operative outcomes of minimally invasive surgery (MIS) versus open surgery for gallbladder cancer in 8,568 patients.
Validation of the lung immune prognostic index in extensive-stage small cell lung cancer: Post hoc analysis of the caspian and IMpower133 phase 3 trials.
This validation study assessed the Lung Immune Prognostic Index (LIPI) in extensive-stage small cell lung cancer (ES-SCLC) using data from the CASPIAN and IMpower133 phase III trials.
Adrenocortical oncocytoma manifesting as primary aldosteronism: a case report.
A 44-year-old man presented with severe hypertension and hypokalaemia, revealing a right adrenal lesion on imaging. Evaluation confirmed primary aldosteronism, with adrenal venous sampling indicating right-sided…
Krukenberg Tumor with Skin Metastasis: A Rare Entity.
A 42-year-old Nepali woman with a history of total gastrectomy for gastric carcinoma presented with prolonged abnormal uterine bleeding and several months of lower abdominal pain.
Primary Osteosarcoma of the First Metatarsal With Multiple Metastases on 18F-FDG PET/CT.
A patient presented with primary osteosarcoma located in the first metatarsal, an uncommon site for this type of tumor. Imaging with 18F-FDG PET/CT revealed multiple metastases, which were later confirmed through…
Effectiveness of enhanced recovery after surgery among cancer patients: A meta-analysis of randomized controlled trials.
This meta-analysis of randomized controlled trials evaluated the effectiveness of enhanced recovery after surgery (ERAS) in cancer patients.
Endoscopic Salvage Following Radiotherapy for Oesophageal Cancer: A Systematic Review.
This systematic review evaluated the safety and efficacy of endoscopic salvage procedures following definitive chemoradiotherapy (dCRT) for locally advanced oesophageal squamous cell carcinoma (OSCC) and adenocarcinoma…
Minimally Invasive Remote Approaches Versus Conventional Open Approach in Central Neck Dissection for Patients Undergoing Total Thyroidectomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared minimally invasive remote approaches (MIRA) to conventional open approaches (COA) for central neck dissection during total thyroidectomy in thyroid cancer patients.
Associations Between Cardiac Radiation Dose-Volume Metrics and Health-Related Quality of Life for Patients With Breast Cancer on the RadComp Trial.
This analysis of the pragmatic randomised RadComp trial examined cardiac radiation doses and health-related quality of life (HRQOL) in 1160 patients with breast cancer who had dose-volume data and baseline plus…
Polysaccharides-mediated mitochondrial remodeling: role in chemotherapy resistance of gastrointestinal tumors.
This systematic review examined the role of mitochondrial remodeling in chemotherapy resistance in gastrointestinal (GI) tumors and evaluated the potential of polysaccharides as therapeutic agents.
Severe Veno-Occlusive Disease in a Child With Wilms Tumor: Acute Management and Subsequent Bridging With Irinotecan Treatment.
A pediatric patient with Wilms tumor developed severe hepatic veno-occlusive disease (VOD) following treatment with dactinomycin and vincristine.
primary analysis of the RANDOMIZED eortc-2139/columbus-ad trial: Adjuvant encorafenib and binimetinib versus placebo in high-risk stage II BRAF-V600E/K melanoma.
The EORTC 2139 - Columbus-AD trial evaluated the efficacy and safety of adjuvant therapy with encorafenib and binimetinib versus placebo in patients with resected high-risk stage IIB/C BRAF V600E/K melanoma.
Multiple myeloma diagnosed after contrast-enhanced computed tomography without renal complications: a case report with literature review.
A 77-year-old woman presented with numbness of the right lower lip, leading to a panoramic radiography that revealed a radiolucent lesion in the right mandible.
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