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1357 articles
October 202624
Incidence and Influencing Factors of Pain Crisis in Cancer Patients: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the incidence of pain crisis and associated factors among people with cancer. Seven studies including 1865 patients were analysed; the pooled incidence was 37%.
Evidence for a time-dependent pain response to platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a cluster-stratified systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of six randomised controlled trials examined how pain outcomes after platelet-rich plasma (PRP) versus corticosteroid injection for lateral elbow tendinopathy varied with…
Large language models for patient-facing consultation in elective aesthetic and appearance-related plastic surgery: a systematic review and exploratory meta-analysis.
This systematic review and exploratory meta-analysis assessed patient-facing large language model (LLM) responses for consultation, education, and perioperative information in elective aesthetic and appearance-related…
Plasma Glutamine and Glutamate in Relation to Clinical Outcomes After Ischemic Stroke: A Multicenter Prospective Study.
This secondary analysis of the multicenter CATIS study examined plasma glutamine (Gln), glutamate (Glu), and their ratio (GGR) in 3499 patients with ischemic stroke.
Effects of anti-inflammatory dietary education on sleep disturbances among patients with breast cancer undergoing chemotherapy: A randomized controlled trial.
This randomized controlled trial assessed whether anti-inflammatory dietary education could improve sleep and related outcomes in 132 patients with breast cancer, sleep disturbances, and ongoing chemotherapy.
Robotic systems in cranial surgery: a systematic review of accuracy, clinical outcomes, and adverse events.
This systematic review examined robotic systems used in cranial neurosurgical procedures and their reported accuracy, clinical outcomes, and adverse events.
Exercise modality and planned weekly exercise exposure for motor outcomes in Parkinson's disease: a systematic review, Bayesian network meta-analysis, and meta-regression.
This systematic review and Bayesian network meta-analysis synthesized 173 randomized trials of exercise in people with Parkinson’s disease, assessing motor symptoms, balance, walking speed, and Timed Up and Go (TUG).
The effect of a stress ball on pain, anxiety, satisfaction, and treatment continuation during extracorporeal shock wave lithotripsy: a randomized controlled trial.
This prospective, two-arm randomized controlled trial assessed whether using a stress ball during extracorporeal shock wave lithotripsy (ESWL) affected pain, anxiety, satisfaction, and continuation among 50 patients…
Bridging evidence gaps in opioid-sparing postoperative pain control for percutaneous nephrolithotomy: a network meta-analysis identifying optimal strategies.
This systematic review and Bayesian network meta-analysis compared postoperative analgesic strategies in adults undergoing percutaneous nephrolithotomy (PCNL), using randomised controlled trials that assessed pain.
Association of virulence genes with biofilm formation in clinical Enterococcus faecalis isolates: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed associations between virulence gene carriage and microplate-measured biofilm formation in human clinical Enterococcus faecalis isolates.
Effect of web-based education on NIV-related side effects and insomnia severity in COPD patients using home NIV: a randomized controlled trial.
This randomized controlled trial evaluated web-based education about NIV-related side effects and insomnia management in 75 patients with COPD using home noninvasive ventilation.
The conformation-selective PI3Kδ inhibitor roginolisib in patients with advanced or metastatic cancer, including metastatic uveal melanoma: first-in-human clinical trial.
This first-in-human, phase I dose-escalation and expansion trial evaluated continuous daily roginolisib in patients with solid and haematologic malignancies.
Women's experiences of a medically supervised fasting intervention for infertility: a qualitative study.
Nested within a randomized controlled trial of medically supervised prolonged fluid-only fasting (< 500 kcal/day) for infertility, this qualitative study explored women’s experiences of the intervention.
The effect of cognitive behavioral therapy for sleep and glycemic outcomes in people with diabetes: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled 10 randomised controlled trials involving 2,827 people with diabetes from four countries to assess cognitive behavioral therapy (CBT) for sleep and glycemic outcomes.
Over-dispersion in malaria-schistosoma co-infection: insights from a meta-analytical approach and systematic review.
This systematic review and meta-analysis assessed malaria–schistosomiasis co-infection patterns in endemic settings, primarily in sub-Saharan Africa, and tested whether co-infections exceeded levels expected if the…
Dose-response effects of robot-assisted training on poststroke functional recovery: A systematic review and meta-analysis.
This systematic review and meta-analysis included 36 randomised controlled trials involving 1941 adults with stroke, comparing robot-assisted training (RAT), alone or with conventional rehabilitation, against…
Stakeholder Perspectives on Digital Health Technologies in Poststroke Self-Management and Rehabilitation: Systematic Review Based on the NASSS Framework.
This systematic review synthesized stakeholder perspectives on digital health technologies (DHTs) for poststroke self-management and rehabilitation, mapping findings to the NASSS framework.
Tofacitinib 20 vs 30 mg in acute severe ulcerative colitis: a double-blind randomized controlled trial.
This double-blind, pilot randomized controlled trial compared tofacitinib 20 mg/day with 30 mg/day, each given alongside intravenous corticosteroids, in adults with acute severe ulcerative colitis.
Dexamethasone versus triamcinolone acetonide for the management of postoperative inflammation following cataract surgery: A systematic review and meta-analysis.
This systematic review and meta-analysis compared dexamethasone with triamcinolone acetonide (TCA) for postoperative inflammation in adults undergoing phacoemulsification.
Efficacy of Kinesio tape for central facial paralysis: A prospective, randomized sham-controlled, single-blinded clinical trial.
This prospective, randomized, single-blind, sham-controlled trial evaluated Kinesio tape (KT) as an adjunct to routine rehabilitation in 121 adults after a first stroke with central facial paralysis.
Faith-based organisations in providing HIV services within low- and middle-income countries (LMICs): a systematic review.
This systematic review assessed empirical studies of faith-based organisations (FBOs) delivering HIV services in low- and middle-income countries.
Rehabilitative efficacy of cognitive behavioral therapy-based intervention for chronic fatigue syndrome: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for fatigue, physical functioning, and psychological health in people with chronic fatigue syndrome.
Comparison of the Efficacy of Appiani and Zuma Maneuvers in Patients with Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo.
This prospective randomized comparative study evaluated the Appiani and Zuma repositioning maneuvers in patients with unilateral apogeotropic horizontal canal benign paroxysmal positional vertigo.
Etrasimod reduces circulating and mucosal inflammatory lymphocyte populations and alters innate immune and non-immune cell signatures in intestinal mucosa: ELEVATE UC phase 3 clinical data.
This analysis of the phase 3 ELEVATE UC randomised trials characterised blood and intestinal mucosal changes in patients with ulcerative colitis treated with etrasimod or placebo.
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