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937 articles
October 202624
Metallic versus plastic stents for the management of biliary obstruction: A GRADE-assessed systematic review and meta-analysis.
This GRADE-assessed systematic review and meta-analysis compared metallic with plastic stents for benign or malignant biliary obstruction, including randomized and observational studies.
A Giant Intra-Abdominal Plasmablastic Neoplasm Favoring Lymphoma Mimicking an Exacerbation of Severe Fistulizing Crohn's Disease: A Case Report.
A 44-year-old woman with severe fistulizing Crohn’s disease developed progressive systemic deterioration despite partial intestinal stabilization.
Etrasimod reduces circulating and mucosal inflammatory lymphocyte populations and alters innate immune and non-immune cell signatures in intestinal mucosa: ELEVATE UC phase 3 clinical data.
This analysis of the phase 3 ELEVATE UC randomised trials characterised blood and intestinal mucosal changes in patients with ulcerative colitis treated with etrasimod or placebo.
Tofacitinib 20 vs 30 mg in acute severe ulcerative colitis: a double-blind randomized controlled trial.
This double-blind, pilot randomized controlled trial compared tofacitinib 20 mg/day with 30 mg/day, each given alongside intravenous corticosteroids, in adults with acute severe ulcerative colitis.
Pancreatic Tuberculosis Mimicking Pancreatic Cancer in a Young Immunocompetent Man: A Case Report and Literature Review.
A 34-year-old HIV-seronegative Afghan man had a year of intermittent epigastric pain, nausea, and vomiting. CT showed a 57×30 mm multiloculated hypoattenuating mass in the pancreatic head without biliary dilation; serum…
Finite Versus Indefinite Nucleos(t)ide Analogue Therapy in HBeAg‑Negative Chronic Hepatitis B: Meta‑Analysis of Randomized Trials.
This meta-analysis evaluated the efficacy and safety of finite versus continuous nucleos(t)ide analogue therapy in HBeAg-negative adults with chronic hepatitis B.
Meckel's diverticulum leading to axial torsion and volvulus of the small bowel.
A patient presented with small-bowel obstruction caused by a giant Meckel’s diverticulum measuring 22 cm × 11 cm × 9.8 cm. The diverticulum produced mass effect and was associated with axial torsion and volvulus of the…
Co-supplementation of zinc and probiotic on oxidative stress markers and sleep quality index in irritable bowel syndrome patients: a double-blind randomized controlled trial.
This parallel, double-blind randomised controlled trial assessed zinc alone and zinc plus probiotics in 84 people with irritable bowel syndrome over 90 days, comparing both with placebo.
Efficacy of direct-acting antiviral regimens for acute HCV infection: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed interferon-free dual direct-acting antiviral regimens for acute or recently acquired HCV infection.
Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.
Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…
Compound-Heterozygous PLVAP Missense Variants Associated With Attenuated Protein-Losing Enteropathy (DIAR10).
A three-year-old girl presented with attenuated protein-losing enteropathy and was found to carry compound-heterozygous missense variants in PLVAP.
Peripheral microbial metabolites as indicators of gut microbiome disruption: systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether circulating microbial metabolites can indicate gut microbiome disruption.
Approach to management of walled-off necrosis secondary to trauma-induced pancreatitis in a limited-resource setting.
A patient with trauma-induced pancreatitis developed a walled-off necrosis (WON) characterized by a necrotic peripancreatic collection. Imaging revealed a mature collection with necrotic debris.
Immune-related colitis following head and neck reconstructive surgery in a patient receiving long-term nivolumab.
A man with gastric cancer, receiving long-term nivolumab and prednisolone for immune-related myositis, underwent subtotal glossectomy for advanced tongue cancer. On postoperative day 4, he developed grade 3 diarrhoea.
Long-Term Effects of Biliopancreatic Diversion (BPD), Biliopancreatic Diversion with Duodenal Switch (BPD-DS), and Single Anastomosis Duodeno‑Ileal Bypass with Sleeve Gastrectomy (SADI‑S) in Patients with Obesity: A Meta-Analysis.
This systematic review and meta-analysis assessed outcomes at 10 or more years after biliopancreatic diversion (BPD), BPD with duodenal switch (BPD-DS), and single-anastomosis duodeno-ileal bypass with sleeve…
CHAPLE-Like Enteropathy and Renal Microangiopathy in an Adult Patient With CD46 Deficiency.
A 23-year-old woman with childhood-onset enteropathy and hypogammaglobulinemia had been treated with immunoglobulin replacement for presumed common variable immunodeficiency.
Gastrointestinal manifestations of IgA vasculitis guiding treatment in an adult patient.
A man in his 20s presented with abdominal pain, post-prandial vomiting, a purpuric rash, arthralgia, and hypertension. Urine studies indicated subnephrotic range proteinuria, and colonoscopy revealed ileal ulceration.
Reduced venesection requirement as a clue to occult colorectal cancer in hereditary haemochromatosis.
A man in his late 70s with hereditary haemochromatosis experienced an unexpected cessation of his usual venesection for iron management, despite no gastrointestinal symptoms or anemia.
Cutaneous leukocytoclastic vasculitis with concurrent colitis of uncertain aetiology.
A female in her 20s presented with biopsy-confirmed cutaneous leukocytoclastic vasculitis and significant gastrointestinal symptoms, including recurrent rectal bleeding and abdominal pain.
Fulminant multi-organ failure associated with cereulide-producing Bacillus cereus after consumption of improperly stored rice.
A previously healthy male in his 20s presented with generalized seizures and severe hypoglycemia after eating improperly stored reheated rice.
Multisystem imaging findings as diagnostic red herrings in Wilson's disease.
A previously healthy man in his 20s presented with fever, cough, jaundice, and a right-sided pleural effusion. Initial tests revealed significant hepatic dysfunction, and imaging showed cirrhotic liver morphology…
Acute autoimmune hepatitis diagnosed concurrently with human immunodeficiency virus.
A woman in her 50s presented with jaundice and severe hepatocellular injury, later diagnosed with advanced HIV infection. Initial considerations included infectious hepatitis, but serology, imaging, and liver biopsy…
Follow-up colonoscopy after abnormal stool-based colorectal cancer screening: a systematic review of completion, timeliness and implementation strategies.
This systematic review examined the completion rates and timeliness of diagnostic colonoscopy following abnormal stool-based colorectal cancer screenings in adults.
Efficacy of Bifidobacterium animalis subsp. lactate BL-99 in relieving functional constipation: a randomized placebo-controlled clinical trial.
This randomized, double-blind, placebo-controlled trial evaluated the efficacy of Bifidobacterium animalis subsp. lactis BL-99 in 41 patients with functional constipation over 6 weeks.
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