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1357 articles
October 202624
Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.
This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.
Progestogens, cervical cerclage, and cervical pessary for preventing preterm birth in asymptomatic singleton pregnancies with a sonographic short cervix and no previous history of spontaneous preterm birth: systematic review and bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared interventions to prevent preterm birth in asymptomatic women with singleton pregnancies, a sonographic short cervix, and no previous spontaneous preterm…
Effectiveness and safety of target-specific RNA-based lipid-lowering therapies: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed the efficacy and safety of RNA-based therapies targeting PCSK9, APOC3, or ANGPTL3 in patients with hyperlipidemia or…
Sustained potassium control and recurrent hyperkalemia during individualized potassium-guided sodium zirconium cyclosilicate titration in maintenance hemodialysis: a post hoc analysis of a randomized trial.
This exploratory post hoc analysis of a single-centre, open-label randomised trial assessed sustained potassium control with individualized potassium-guided sodium zirconium cyclosilicate (SZC) in 116 maintenance…
Negotiating Care Over Time: A Systematic Review of Alzheimer's Disease Caregiving Through a Life Course Approach.
This systematic review examined sociological research published between 2004 and 2024 on family caregiving for people with Alzheimer’s disease, focusing on how caregiving intersects with caregivers’ life trajectories…
How Do Mindfulness-Based and Cognitive Behavioral Therapies Help Adults With Opioid-Treated Chronic Low Back Pain? A Qualitative Study.
This qualitative study explored how mindfulness-based therapy (MBT) and cognitive behavioral therapy (CBT) may help adults with chronic low back pain treated with opioids.
Necroptosis as a key player in cervical cancer progression and management: a systematic review and transcriptomic cross-study consensus analysis.
This systematic review and transcriptomic cross-study consensus analysis examined published evidence on necroptosis in cervical cancer, including seven prognostic gene models and exploratory analyses of overlapping…
Can't Name It, Can't Log Off: Alexithymia and Problematic Internet-Related Behaviors: A Systematic Review and Meta-Analysis.
This preregistered systematic review and meta-analysis examined quantitative associations between alexithymia and problematic Internet-related behaviors (PIB), including problematic Internet, smartphone, social media…
Inhibin B as a biomarker for ovarian reserve and ovarian response: systematic reviews and meta-analyses of diagnostic test accuracy.
This systematic review and meta-analysis assessed the diagnostic accuracy of inhibin B compared with anti-Müllerian hormone (AMH) for ovarian reserve and ovarian response.
Effects of gliflozins on bone health of patients with chronic kidney disease: a systematic review.
This systematic review assessed skeletal safety and bone-related metabolic outcomes with sodium-glucose co-transporter-2 inhibitors (SGLT2i) in people with chronic kidney disease, drawing on randomised trials and…
Dropout from individual cognitive behavioral psychotherapy for schizophrenia: a systematic review and meta-analysis of randomized clinical trials.
This secondary analysis of a systematic review and meta-analysis examined dropout from individual, face-to-face outpatient cognitive behavioral therapy (CBT) for schizophrenia spectrum disorders.
Impact of HIF-prolyl hydroxylase inhibitors on VEGF expression and vascular adverse events in chronic kidney disease: a meta-analysis of 34 randomized controlled trials.
This meta-analysis of 34 randomized controlled trials assessed VEGF levels and VEGF-related adverse outcomes with hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) in people with chronic kidney disease.
Preclinical and clinical evaluation of an ocular nanoemulsion for the treatment of dry eye disease.
This study evaluated a preservative-free castor oil and sodium hyaluronate nanoemulsion (VSLB) for dry eye disease in a scopolamine-induced rat model and a prospective, randomized, double-masked clinical study of 64…
EORTC QLQ-C30 symptom components and their functional correlates during adjuvant chemotherapy for early breast cancer: a multivariate analysis. Data from GEICAM/2003-02 study.
This multivariate analysis of data from a multicentre phase III randomised trial examined changes in EORTC QLQ-C30 symptoms and their relationships with functioning among 820 patients with early breast cancer receiving…
Integrated management of atrial fibrillation with digital health support: a pooled analysis of individual participant data from the mAFA-II and MIRACLE-AF trials.
This pooled individual participant data analysis combined two prospective randomised trials of adults with atrial fibrillation: mAFA-II, which delivered ABC pathway care through a mobile app, and MIRACLE-AF, which used…
Body Mass Index, Valsartan, and Myocardial Remodeling in Early-Stage Hypertrophic Cardiomyopathy: A Secondary Analysis of the Randomized VANISH Trial.
This post hoc analysis of the randomized, multicenter VANISH trial examined BMI and cardiac remodeling in participants with early-stage hypertrophic cardiomyopathy. Of 171 participants, 52% had elevated BMI.
Assisted Reproductive Technology and Risk of Congenital Heart Defects in the Offspring: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed congenital heart defect (CHD) risk in offspring conceived through assisted reproductive technology (ART) compared with spontaneous conception.
Exploring the Neural Mechanisms of Acupuncture Stimulation in Autism Spectrum Disorder: Protocol for a Randomized, Sham-Controlled, Multimodal Neuroimaging Trial.
This protocol describes a randomized, sham-controlled, stratified 2×2 trial designed to examine brain differences associated with autism spectrum disorder (ASD) and the acute neural response to acupuncture.
Omega-6 Polyunsaturated Fatty Acids and Peripheral Artery Disease: An Individual Participant-Level Analysis of 9 International Prospective Studies.
This multicohort individual participant-level analysis and meta-analysis examined baseline omega-6 polyunsaturated fatty acids and incident peripheral artery disease (PAD) among 137,704 participants without clinical PAD…
Genetic Variants in Intracranial Atherosclerotic Disease: A Systematic Review and Targeted Meta-Analysis Highlighting the RNF213 rs112735431.
This systematic review and targeted meta-analysis examined genetic variants associated with intracranial atherosclerotic disease (ICAD) in human studies identified through September 2025.
Pilot Randomized Trial of 2 Food Purchasing Interventions in Individuals With Hypertension in New Orleans: An American Heart Association Food Is Medicine Initiative.
This randomized pilot trial compared online and in-store food vouchers among 98 people with uncontrolled hypertension in New Orleans.
Application of antibiotic-loaded bone cement in unicompartmental knee arthroplasty: inhibiting IL-6 levels and reducing postoperative infection rate.
This prospective randomized controlled trial compared antibiotic-loaded bone cement (ALBC) containing 1.0 g vancomycin hydrochloride with cement without antibiotics in 104 patients with osteoarthritis undergoing…
Impact of Evolocumab on LDL-Cholesterol and Cardiovascular Outcomes in Patients With Established CVD: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled randomised controlled trials of evolocumab in adults with established cardiovascular disease.
Comparison of Clinical, Metabolic, and Hormonal Profiles in Obese Versus Lean Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis compared clinical, metabolic, and hormonal profiles in obese and lean women with polycystic ovary syndrome (PCOS).
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