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1357 articles
October 202624
Blood pressure targets in adults with hypertension.
This publication is a protocol for a Cochrane intervention review, not a report of completed results. It sets out to assess lower blood pressure targets (≤ 135/85 mmHg) versus standard targets (≤ 140 to 160/90 to 100…
The impact of kinesiotaping on functional respiratory outcome in chest injuries-a pilot randomized trial.
This pilot randomized trial compared kinesiotaping (KT) plus breathing exercises with breathing exercises alone in 34 patients with isolated unilateral injuries involving fewer than five ribs.
Stereotactic body radiotherapy versus conventional external beam radiotherapy for bone metastases: a meta-analysis.
This systematic review and meta-analysis compared stereotactic body radiotherapy (SBRT) with conventional external beam radiotherapy (cEBRT) for painful bone metastases, pooling comparative clinical studies using…
Laparoscopic and robotic management of symptomatic calyceal diverticula: a systematic review on behalf of YAU and EAU endourology.
This systematic review assessed laparoscopic and robot-assisted management of symptomatic calyceal diverticula. Nine studies were included in a qualitative synthesis.
Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.
This systematic review synthesised 27 studies of FOXP3+ regulatory T-cell (Treg) phenotype and function in human and experimental Trypanosoma cruzi infection: 9 human studies and 18 murine studies.
Resilience interventions for stress-related health outcomes in patients with cancer: Findings from a systematic review of randomized controlled trials.
This systematic review synthesized randomized controlled trials of resilience interventions for stress-related health outcomes in patients with cancer.
Anatomical variation in the cervical branch of the facial nerve: a systematic review.
There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…
Next-generation pharmacological strategies for Parkinson's disease: a systematic literature review of symptom management and disease modification.
This PRISMA 2020 systematic literature review assessed pharmacological and emerging therapeutic strategies for symptom management and disease modification in Parkinson disease.
Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.
This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.
Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.
This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…
Menstrual health challenges and associated barriers among tribal adolescent girls in India: A systematic review.
This systematic review synthesised quantitative, qualitative and mixed-methods research on menstrual health among tribal adolescent girls in India.
Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement: A PRO-TAVI Substudy.
This post hoc substudy of the multicentre randomised PRO-TAVI trial examined whether coronary disease complexity, measured by SYNTAX score, was associated with outcomes among 466 patients with significant coronary…
Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI: A Meta-Analysis of Randomized Trials.
This frequentist meta-analysis of four multicentre randomised trials compared immediate with staged complete revascularization in 2,651 patients with STEMI and multivessel disease.
Improvement in peripheral airway function after a 12-week exercise intervention in COPD.
This prospective, multicenter, single-arm non-randomized intervention study assessed lung function, exercise capacity and symptoms before and after a 12-week supervised exercise program in 62 people with COPD.
Osteopathic manual therapy in fibromyalgia: a pilot study.
This pilot randomised controlled trial assessed whether adding osteopathic manual therapy to Clinical Pilates improved pain, symptom severity, pressure pain threshold, and sleep in 20 women with fibromyalgia.
The effectiveness of guided botulinum toxin "A" injection to the masticatory muscles in the management of condylar and sub condylar fractures: a randomized controlled clinical trial.
This randomized controlled clinical trial compared ultrasound-guided botulinum toxin A injections into the masseter, temporalis and lateral pterygoid muscles plus closed reduction with closed reduction alone in 16…
Analgesic efficacy of uni-level erector spinae plane block in breast cancer surgery patients: a systematic review and Meta-analysis.
This systematic review and meta-analysis assessed uni-level erector spinae plane block (ESPB) as an adjunct to general anesthesia and opioids for breast cancer surgery.
Oral eplerenone in first-episode acute central serous chorioretinopathy: results of a double-masked randomized trial.
This double-masked, randomized, placebo-controlled trial evaluated oral eplerenone in 44 patients with first-episode acute central serous chorioretinopathy (CSCR).
Robotic-assisted versus conventional coronary artery bypass grafting: a systematic review, meta-analysis, and trial sequential analysis of 39,918 patients.
This systematic review and meta-analysis compared robotic-assisted with conventional coronary artery bypass grafting (CABG) across nine observational studies involving 39,918 patients.
Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.
This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…
Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.
This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.
Randomized Trial of Hypofractionated Postmastectomy Radiation Therapy in Women With Breast Reconstruction (RT CHARM, Alliance A221505).
RT CHARM (Alliance A221505) was a randomized noninferiority trial comparing hypofractionated with conventional postmastectomy radiation therapy in women with unilateral invasive breast cancer undergoing immediate or…
The role of fibrinogen concentrate in the reduction of allogeneic blood product requirements: a systematic review and meta-analysis.
This systematic review and meta-analysis compared fibrinogen concentrate (FC) with other treatments for acquired hypofibrinogenaemia across clinical settings.
Assessment of Autism Spectrum Disorder in Gender-Diverse Populations: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined how autism spectrum disorder (ASD) and autistic traits are assessed in gender-diverse populations.
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