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1382 articles
April 202624
The effect of the healthy lifestyle 'empowerment program' on care burden and adherence to health-promoting behaviours on mothers of children with type 1 diabetes.
This randomized controlled trial assessed the Healthy Lifestyle Empowerment Program (HLEP) for mothers of children with type 1 diabetes (T1D) in Tehran.
Varenicline for nicotine cessation in youth: A meta-analysis of randomized controlled trials addressing FDA labeling gaps in age and product use.
This meta-analysis evaluated the effectiveness and safety of varenicline for nicotine cessation in young adults aged 12 to 26 years, analyzing data from five randomized controlled trials.
Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock.
This randomized controlled trial evaluated the effects of balanced crystalloid fluid versus 0.9% saline in 8,482 children aged 2 months to <18 years with suspected septic shock.
Cornelia de Lange syndrome in an extremely low birth weight infant: a case report.
An infant born by emergency cesarean delivery at 34 weeks and 1 day weighed 994 g (-3.7 SD score). Cornelia de Lange syndrome (CdLS) was suspected from dysmorphic findings including forehead and femoral hirsutism, cleft…
Clinical Significance of Renal Tissue in Neonatal Sacrococcygeal Teratoma: A Case Report With Review of Literature.
A neonate with a sacrococcygeal teratoma (SCT) had renal differentiation within the tumor, including a minor component interpreted as nephroblastoma.
Electrochemotherapy in pediatrics: a systematic review.
This systematic review evaluated electrochemotherapy (ECT) in pediatric patients, analyzing 15 studies involving at least 127 children.
Maternal Chikungunya virus infection and pregnancy outcomes: a global systematic review and meta-analysis of vertical transmission dynamics and associated morbidity.
This systematic review and meta-analysis evaluated the impact of maternal Chikungunya virus (CHIKV) infection on pregnancy outcomes, analyzing 57 observational studies.
Ultrasound Diagnosis of Giant Testicular Adrenal Residual Tumors: A Case Report and Literature Review.
A 9-year-old male with congenital adrenal hyperplasia presented with giant testicular adrenal residual tumors (TARTs) associated with 11β-hydroxylase deficiency.
Elevated serum creatinine over the first week of life and mortality risk in extremely preterm neonates: a secondary analysis of the Preterm Erythropoietin Neuroprotection Trial (PENUT).
This secondary analysis of the Preterm Erythropoietin Neuroprotection Trial evaluated the association between elevated serum creatinine (SCr) levels and mortality risk in extremely preterm neonates (<28 weeks…
Distal humerus physeal fractures in children under 3 years: a systematic review and quantitative descriptive analysis.
To conduct a systematic review on the imaging diagnosis and modality-specific characterization of distal humerus physeal fractures among children under 3 years of age.
Comparing Buzzy Ⓡ and Pikluc Ⓡ for Pain Relief in Pediatric Intramuscular Injections: A Randomized Equivalence Trial.
This randomized equivalence trial evaluated the effectiveness of Buzzy Ⓡ and Pikluc Ⓡ for pain relief during intramuscular injections in children aged 1-11 years.
Delayed versus Early Umbilical Cord Clamping in Preterm Multiple Gestation: A Randomized Controlled Trial.
This randomized controlled trial evaluated the effects of delayed cord clamping (DCC) versus early cord clamping (ECC) in 155 preterm infants from multiple gestations.
Efficacy of probiotics in vancomycin-resistant enterococci decolonization: A meta-analysis of randomized clinical trials.
This meta-analysis of randomized clinical trials assessed probiotics for vancomycin-resistant enterococci (VRE) decolonization, including subgroup analyses by treatment duration, strain, and age.
False Positive Findings on 18F-MFBG PET/CT Attributable to Benign Neural Differentiation in a Pediatric Patient With Neuroblastoma.
A 5-year-old girl with high-risk neuroblastoma underwent an 18F-MFBG PET/CT scan to evaluate indeterminate lesions seen on prior imaging.
Circulating Piwi-Interacting RNAs Associate With Childhood Asthma ICS Response With Vitamin D Effect Modification.
This randomized controlled trial investigated the association of circulating piwi-interacting RNAs (piRNAs) with inhaled corticosteroid (ICS) response in 492 children with asthma.
A Case Report of I-Cell Disease (Mucolipidosis Type II) With a Novel Placental-Focused Diagnostic Approach.
A neonate was admitted to the NICU with respiratory distress and initial concern for infection. Placental examination showed vacuolization of syncytiotrophoblasts, with intracytoplasmic lipid vacuoles highlighted by Oil…
Hand, foot, and mouth disease: A systematic review of global evidence, climatic drivers, and research gaps (2000-2023).
This systematic review analyzed 125 studies on hand, foot, and mouth disease (HFMD) from 2000 to 2023, primarily focusing on children under five.
Foreign Body Aspiration Presenting as Recurrent Bronchiolitis: Case Report.
A toddler presented with recurrent wheezing and cough that did not improve with standard treatment. Evaluation at a pediatric urgent care center raised concerns for airway obstruction, leading to transfer to a pediatric…
A Novel YY1AP1 Variant in Grange Syndrome: Clinical and Molecular Findings in Eight Individuals With a Dual Molecular Diagnosis Involving CLMP in One Patient.
This report describes eight individuals from a consanguineous family diagnosed with Grange syndrome, characterized by multiple fractures, bone fragility, and other systemic manifestations.
Sweep Flow Nitric Oxide Effects on Coagulation, Inflammation, and Endothelial System Activation During Extracorporeal Membrane Oxygenation.
This randomized controlled trial assessed whether sweep-flow nitric oxide (sNO) altered inflammatory, endothelial, and coagulation biomarkers in 53 neonates and children receiving ECMO, and examined biomarker patterns…
Acquired Syphilis in a Family Cluster Without Evidence of Sexual Transmission.
A family cluster presented with multiple cases of acquired syphilis in pediatric patients, with no evidence of sexual transmission. The index case and a sibling were evaluated, revealing no signs of sexual abuse.
Endoscopic-Assisted Transcervical Excision of Second Branchial Cleft Anomalies in Young Children.
This report details the use of an endoscopic-assisted transcervical technique for excising second branchial cleft anomalies in three young children aged 2 to 8 years.
The Effect of Virtual Reality on Pain Management in Children in the Emergency Department: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of virtual reality on pain and anxiety management in children aged 2-17 undergoing medical procedures in emergency departments.
Management and presentation of pediatric thyroid eye disease: A systematic review and meta-analysis.
BackgroundPediatric Thyroid Eye Disease (TED) is a rare autoimmune condition primarily associated with Graves' disease. Although usually milder than adult TED, it can still cause functional and psychological morbidity.
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