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1357 articles

October 202624

Clinical ResearchPulmonology

Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchCardiologyOpen access

Fibro-Inflammatory Signaling, Fibrosis, and Microvascular Ischemia as Convergent Translational Substrates of Sudden Cardiac Death in Hypertrophic Cardiomyopathy: A Systematic Review.

This systematic translational review examined whether fibro-inflammatory signaling, fibrosis, and microvascular ischemia converge as substrates for ventricular arrhythmia and sudden cardiac death in hypertrophic…

J Cardiovasc Transl ResOct 13, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review of Academic Performance and Well-Being in University Students.

This systematic review synthesized 11 observational, cross-sectional studies of female medical and health sciences students published between January 2014 and December 2024.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchGeriatrics

Effects of aquatic and land-based resistance training on hip bone health in overweight older women: A 32-week randomized controlled trial.

This secondary analysis of a six-arm randomized controlled trial compared supervised aquatic and land-based elastic resistance training with control in 98 older women with overweight.

Arch Gerontol GeriatrOct 13, 2026Read summary
Clinical ResearchPediatrics

Cost comparison of the ShangRing device versus Mogen clamp for early infant male circumcision in Sub-Saharan Africa.

This cost comparison alongside a randomized controlled trial assessed early infant male circumcision using the ShangRing (SR) versus the Mogen clamp (MoC) among infants aged 0–60 days in Kenya, Tanzania, and Uganda.

PLoS OneOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

The dual burden of disease: Depression among patients with multidrug resistance tuberculosis in low-income and lower- middle-income countries: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated depression prevalence and examined associated factors among patients with multidrug-resistant tuberculosis (MDR-TB) in low- and lower-middle-income…

PLoS OneOct 13, 2026Read summary
Clinical ResearchOphthalmology

USB-powered vs. self-heating warm compresses for meibomian gland dysfunction: A prospective randomized crossover clinical trial.

This prospective randomized crossover trial compared USB-powered and self-heating warm compresses in 15 adults aged 18–40 years with meibomian gland dysfunction and tear break-up time ≤10 s.

PLoS OneOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Six-month supervised telerehabilitation combining pilates-based therapeutic exercise and self-myofascial release in adults with fibromyalgia: a randomized controlled trial.

This two-arm randomized controlled trial evaluated a six-month supervised home-based telerehabilitation programme in 68 adults with fibromyalgia confirmed by 2016 ACR criteria.

J Rehabil MedOct 13, 2026Read summary
Clinical ResearchCardiology

Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function.

This double-blind, randomized crossover trial examined whether a meal-induced rise in plasma ceramides impairs in vivo microvascular function in 23 healthy young adults.

Am J Physiol Heart Circ PhysiolOct 13, 2026Read summary
Clinical ResearchPediatrics

Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…

PLoS OneOct 13, 2026Read summary
Clinical ResearchNephrology

Haemodiafiltration, haemofiltration and haemodialysis for adults with kidney failure.

This Cochrane systematic review and meta-analysis assessed randomised trials comparing convective dialysis (haemofiltration, haemodiafiltration or acetate-free biofiltration) with diffusive haemodialysis or expanded…

Cochrane Database Syst RevOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.

This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…

BMC Musculoskelet DisordOct 13, 2026Read summary
Clinical ResearchPediatrics

Impact of a Dynamic Visualized Pain Assessment Tool on Pediatric Pain Management: A Stepped-Wedge Cluster Randomized Trial.

This stepped-wedge cluster randomized trial evaluated a dynamic visualized pain assessment tool across five clinical wards, involving 15 infants and 45 video segments spanning baseline, procedural pain, and…

J Vis ExpOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Refining Home-Based Squat Training: The Role of Hip Adduction in Improving Neuromuscular Control for Clinically Diagnosed Patellofemoral Pain Syndrome.

This randomized controlled trial compared an 8-week home-based squat program with and without hip adduction in 30 participants with clinically diagnosed patellofemoral pain syndrome (PFPS); both groups also performed…

Med Sci MonitOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

Epigenetic insights into anti-tuberculosis drug-induced liver injury: A systematic review of DNA methylation as a potential biomarker.

This systematic review assessed whether DNA methylation patterns are associated with susceptibility to anti-tuberculosis drug-induced liver injury (ATDILI).

Eur J PharmacolOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Developing and evaluating a remote, self-administered, AI-powered occupational therapy initial assessment: A crossover randomized controlled trial.

This crossover randomized controlled trial compared a remote, self-administered AI occupational therapy (OT) initial assessment with a human-administered assessment in 30 adults.

WorkOct 13, 2026Read summary
Clinical ResearchPsychiatry

Augmentation strategies for intravenous ketamine in treatment-resistant depression: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed augmentation strategies intended to sustain or improve the effects of intravenous ketamine in adults with treatment-resistant depression.

J Affect DisordOct 12, 2026Read summary
Clinical ResearchPsychiatry

Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.

This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…

Dialogues Clin NeurosciOct 12, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of adjunctive mitochondrial modulators for bipolar depression: A comprehensive systematic review and network meta-analysis.

This systematic review and network meta-analysis compared adjunctive mitochondrial modulators for depressive symptoms in adults with bipolar depression, using evidence from 22 double-blind randomised controlled trials.

J Affect DisordOct 12, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).

This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…

BMC Oral HealthOct 12, 2026Read summary
Clinical ResearchUrologyOpen access

Robot-assisted ileal ureter replacement for complex ureteral strictures: a systematic review and single-arm meta-analysis of surgical and functional outcomes.

This systematic review and single-arm meta-analysis assessed surgical and functional outcomes after robot-assisted ileal ureter replacement (RIUR) in adults with complex ureteral strictures.

J Robot SurgOct 12, 2026Read summary
Clinical ResearchUrologyOpen access

Comparative perioperative outcomes of Hugo™ RAS versus laparoscopic and Da Vinci platforms for partial nephrectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis compared Hugo™ RAS with da Vinci-assisted and laparoscopic partial nephrectomy. It included four observational cohort studies comprising 383 patients.

J Robot SurgOct 12, 2026Read summary
Clinical ResearchPediatrics

Home visits following hospital discharge for families with preterm and low-birthweight infants.

This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.

Cochrane Database Syst RevOct 12, 2026Read summary
Clinical ResearchOncology (Medical)

Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.

This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…

Acta OncolOct 12, 2026Read summary

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