Trending archive
Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.
2000 articles
August 202624
Comparison of the outcomes of ileal pouch-anal anastomosis and ileorectal anastomosis for patients with familial adenomatous polyposis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated outcomes of ileal pouch-anal anastomosis (IPAA) versus ileorectal anastomosis (IRA) in 4700 patients with familial adenomatous polyposis.
Emotional freedom techniques for cancer-related sleep disturbance and associated symptoms: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of Emotional Freedom Techniques (EFT) for alleviating sleep disturbances in cancer patients.
Axillary Surgery in Sentinel Node-Positive Breast Cancer After Neoadjuvant Therapy: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the outcomes of axillary lymph node dissection (ALND) versus omission of ALND in patients with sentinel node-positive breast cancer after neoadjuvant therapy.
Immune checkpoint inhibitors in the management of oral mucosal melanoma.
Oral mucosal melanoma (OMM) is a rare, aggressive malignancy biologically distinct from cutaneous melanoma. Given complex anatomy and limited chemotherapy efficacy, immune checkpoint inhibitors (ICIs) are increasingly…
Intestine as the Exclusive Site of Distant Metastasis From Lung Adenocarcinoma Detected on 18 F-FDG PET/CT.
A 77-year-old man with lung adenocarcinoma underwent 18F-FDG PET/CT, which showed a moderately hypermetabolic pulmonary nodule and two intensely hypermetabolic intestinal lesions.
Bile Cell-Free DNA as a Tumor-Proximal Source for Molecular Profiling of Biliary Tract Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed bile cell-free DNA (cfDNA) for molecular profiling in biliary tract cancer. Eight studies involving 271 patients were included.
Patient-reported outcomes with tarlatamab in extensive-stage small cell lung cancer after platinum-based chemotherapy: results from the phase 3 DeLLphi-304 trial.
The phase 3 DeLLphi-304 trial evaluated patient-reported outcomes (PROs) in adults with extensive-stage small cell lung cancer (ES-SCLC) receiving tarlatamab versus standard-of-care chemotherapy after platinum-based…
A phase 2 study of encorafenib in combination with binimetinib for Chinese participants with BRAF V600E mutated metastatic non-small cell lung cancer: Results from the OCEAN II study.
The OCEAN II study, a phase 2 clinical trial, evaluated the efficacy and safety of encorafenib combined with binimetinib in 63 Chinese participants with BRAF V600E-mutated metastatic non-small cell lung cancer.
The variant c.2766+3A>T in DPYD leads to exon 21 skipping and is associated with DPD deficiency and severe fluoropyrimidine toxicity.
A 50-year-old man with colorectal cancer developed life-threatening grade 3–4 toxicity while receiving adjuvant XELOX (oxaliplatin and capecitabine). Routine DPYD genotyping found no pathogenic variants.
SYS6010, epidermal growth factor receptor-targeting antibody-drug conjugate for advanced non-small cell lung cancer: A phase 1 trial.
This phase 1 trial evaluated SYS6010, an antibody-drug conjugate targeting EGFR, in 236 patients with advanced non-small cell lung cancer (NSCLC).
Distress Intolerance: Dialectical Behavior Therapy Informed Communication for Serious Illness Care.
A patient with advanced cancer exhibited significant emotion dysregulation and low distress tolerance, impacting their communication with the medical team and causing distress among clinicians.
Matching-adjusted indirect comparison of fruquintinib versus ramucirumab in advanced gastric or gastroesophageal junction adenocarcinoma.
This study conducted a matching-adjusted indirect comparison of fruquintinib plus paclitaxel versus ramucirumab plus paclitaxel in patients with advanced gastric or gastroesophageal junction adenocarcinoma.
Pain management after major oncological breast surgery: an updated systematic review and procedure specific postoperative pain management (PROSPECT) recommendations.
This PROSPECT systematic review updated recommendations for peri-operative pain management after major oncological breast surgery, assessing randomised controlled trials and systematic reviews.
COMBI-I: Long-Term Overall Survival With Spartalizumab Plus Dabrafenib and Trametinib in BRAF V600-Mutant Advanced Melanoma.
The COMBI-I trial, a randomized controlled trial, assessed the efficacy of spartalizumab combined with dabrafenib and trametinib in 267 patients with BRAF V600-mutant advanced melanoma.
Multiple Radioiodine-avid Skin Metastases From Thyroid Carcinoma Detected on Posttherapy 131 I SPECT/CT.
A 77-year-old man with papillary thyroid carcinoma had achieved remission after radioactive iodine treatment for metastatic disease.
SSTR Antagonist PET/CT Unveils Occult Hepatic Metastases in Rectal Neuroendocrine Tumor: Superiority Over 68 Ga-DOTANOC and Clinical Upstaging.
68 Gallium NODAGA-JR11, a somatostatin receptor (SSTR) antagonist, exhibits superior sensitivity in detecting hepatic metastases of neuroendocrine tumors compared with the agonist tracer 68 Ga-DOTANOC PET/CT.
Multitarget Molecular Imaging-based Characterization of Gastrointestinal Stromal Tumor.
An incidental gastric gastrointestinal stromal tumor (GIST) was identified and evaluated using three separate PET radiopharmaceuticals.
Response-adapted surgical de-escalation following neoadjuvant immunotherapy in resectable mucosal HNSCC A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of response-adapted surgery (RAS) following neoadjuvant immunotherapy in 202 patients with resectable mucosal head and neck squamous cell…
Personalized Sedation Goals for Agitated End-of-Life Delirium: Secondary Analysis of RECORD Trial.
This preplanned secondary analysis of a multicenter, double-blind randomized trial assessed whether treatments achieved caregiver-defined personalized sedation goals in patients with advanced cancer and persistent…
Efficacy and safety of endoscopic resection followed by chemoradiotherapy with S-1 plus cisplatin for esophageal cancer.
This single-centre, single-arm exploratory phase II study assessed endoscopic resection (ER) followed by chemoradiotherapy (CRT) with S-1 plus cisplatin in patients with superficial esophageal squamous cell carcinoma…
Metastatic Breast Cancer to the Cervix and Endometrium Mimicking a Primary Gynecologic Malignancy.
A 56-year-old postmenopausal woman with a history of metastatic invasive mammary carcinoma presented after experiencing heavy vaginal bleeding and a syncopal event.
Positive Margin Rate Following Transoral Surgery in T2-T3 Laryngeal Carcinoma - a Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the positive margin rate following transoral endoscopic surgery in 3,281 patients with T2-T3 laryngeal carcinoma.
MicroRNAs in IPF and lung cancer: convergent and divergent mechanisms: a systematic review.
This systematic review examines the role of microRNAs (miRNAs) in idiopathic pulmonary fibrosis (IPF) and lung cancer (LC), highlighting shared and distinct mechanisms.
Autologous dermal flap techniques beyond inferior dermal flap coverage in implant-based breast reconstruction: A systematic review.
While inferior dermal flap (IDF) techniques are gaining popularity for implant-based reconstruction (IBBR), a range of autologous dermal flap (ADF) modifications have been described that serve purposes beyond standard…
Showing the most recent matches. Add a word or a date to reach older ones.
Stay updated for free
Get the 3 most interesting publications in one specialty each week.
Weekly email. Unsubscribe anytime.
Want this personalized?
Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.
- Your specialties
- Your filters and thresholds
- Clinical Research + Case Reports, tuned separately
- Automatic weekly delivery
- Audio and text
Prefer listening? Personalized audio digests are available with Pro.