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2000 articles

August 202624

Clinical ResearchOncology (Medical)

Beyond predictive performance: A systematic review and critical methodological appraisal of AI/ML and conventional modelling strategies in breast, colorectal, and pancreatic Cancer.

This systematic review evaluated the methodological performance of AI/ML models versus conventional logistic regression and Cox proportional hazards models in predicting outcomes for breast, colorectal, and pancreatic…

Artif Intell MedAug 17, 2026Read summary
Clinical ResearchOncology (Medical)

Eight-year outcomes of testosterone suppression plus enzalutamide or a nonsteroidal antiandrogen for metastatic hormone-sensitive prostate cancer (ENZAMET; ANZUP 1304).

ENZAMET was a phase III, multicentre randomised trial comparing enzalutamide with a first-generation nonsteroidal antiandrogen (NSAA), each given with testosterone suppression, in participants with metastatic…

Ann OncolAug 17, 2026Read summary
Clinical ResearchOncology (Medical)

Total thyroidectomy versus limited thyroidectomy for isthmic papillary thyroid carcinoma: a systematic review and meta-analysis of oncologic outcomes and surgical morbidity.

This systematic review and meta-analysis compared oncologic outcomes and surgical complications after total versus limited thyroidectomy for isthmic papillary thyroid carcinoma.

J Endocrinol InvestAug 17, 2026Read summary
Clinical ResearchOncology (Medical)

Induction TPF versus adjuvant PF after CCRT in locally advanced nasopharyngeal carcinoma: A multicenter, randomized controlled phase III clinical trial.

This multicenter, randomized controlled phase III trial evaluated the efficacy and safety of TPF induction chemotherapy combined with concurrent chemoradiotherapy (CCRT) versus CCRT followed by PF adjuvant chemotherapy…

Radiother OncolAug 16, 2026Read summary
Clinical ResearchOncology (Medical)

Preoperative stereotactic body radiotherapy for early-stage luminal breast cancer: a systematic review and meta-analysis (PRELUMEN).

This systematic review and meta-analysis evaluated preoperative stereotactic body radiotherapy (SBRT) in 428 patients with early-stage luminal breast cancer.

Radiother OncolAug 16, 2026Read summary
Clinical ResearchPulmonology

Diagnostic performance of machine learning models for malignant and non-malignant pleural effusion: Systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic performance of machine learning models in distinguishing malignant pleural effusion (MPE) from non-malignant pleural effusion.

Int J Med InformAug 16, 2026Read summary
Clinical ResearchOncology (Medical)

Sexual intimacy after breast cancer: A systematic review of qualitative studies on women's and partners' experiences in dating and romantic relationships.

This systematic review synthesizes qualitative studies on the impact of breast cancer on sexual intimacy and romantic relationships, including partners' perspectives.

Body ImageAug 15, 2026Read summary
Clinical ResearchOncology (Medical)

The role of circulating tumor cell dynamics in the prognosis of colorectal cancer: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether circulating tumor cell (CTC) measurements track treatment response and prognosis in colorectal cancer. It included 18 cohort studies involving 2838 patients.

Crit Rev Oncol HematolAug 15, 2026Read summary
Clinical ResearchOncology (Medical)

Acute Radiation Side Effects of Proton Versus Photon Therapy Following Surgery for Early Breast Cancer, a Substudy of the Randomized Controlled Danish Breast Cancer Group Proton Trial.

This preplanned substudy of a phase 3 randomized trial compared acute side effects of moderately hypofractionated proton therapy (PT) and photon radiation therapy (γRT) after surgery for invasive breast cancer or ductal…

Int J Radiat Oncol Biol PhysAug 14, 2026Read summary
Clinical ResearchOncology (Medical)

Quality of surgical reporting and adequacy of surgical treatment in salivary gland cancer: a quality assurance ancillary study of the GORTEC 2016-02 SANTAL trial.

This ancillary study of the GORTEC 2016-02 SANTAL randomized trial evaluated surgical reporting and treatment adequacy in 87 patients with salivary gland carcinomas across 26 centers.

Eur J Surg OncolAug 14, 2026Read summary
Clinical ResearchGastroenterology

Efficacy of probiotic and synbiotic supplementation on antibiotic use duration and risk of postoperative infection in patients undergoing gastrointestinal and cancer-related surgery: An umbrella review of meta-analyses.

This umbrella review assessed the impact of synbiotic and probiotic supplementation on antibiotic use duration and postoperative infection risk in patients undergoing gastrointestinal and cancer-related surgery.

Clin Nutr ESPENAug 14, 2026Read summary
Clinical ResearchOncology (Medical)

A Sentiment-Based Comparison of AI- and Physician-Generated Empathic Statements in Palliative Care.

This randomized controlled trial analyzed patient preferences for AI-generated versus physician-generated empathic statements in palliative care among 105 cancer patients.

J Pain Symptom ManageAug 14, 2026Read summary
Case ReportGeneral SurgeryOpen access

Salvage pancreaticoduodenectomy for localized recurrence after resection of ascending colon cancer: a case report.

A 66-year-old man underwent right hemicolectomy for ascending colon cancer directly invading the gallbladder; pathology showed T4bN0M0, Stage IIC disease with a KRAS G12D mutation.

Clin J GastroenterolAug 14, 2026Read case
Case ReportOncology (Medical)

Uncommon Concurrent Retinal and Cerebral Metastasis in High-risk Neuroblastoma: Diagnostic Utility of 68Ga-DOTATATE PET/CT Despite Negative 18F-FDG PET/CT.

A 5-year-old girl with high-risk neuroblastoma presented for surveillance with an 18F-FDG PET/CT, which showed two metabolically silent lesions in the right retina and brain.

Clin Nucl MedAug 14, 2026Read case
Clinical ResearchNuclear MedicineOpen access

68 Ga-granzyme B ( 68 Ga-NOTA-GSI) PET/CT for predicting immunotherapy response and progression free survival in NSCLC.

This prospective, single-centre trial evaluated ⁶⁸Ga-NOTA-GSI PET/CT after two treatment cycles in 41 patients with stage IIIB/IV non-small cell lung cancer receiving immunotherapy.

Eur J Nucl Med Mol ImagingAug 14, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Robotic left transthoracic left main bronchial sleeve resection with preoperative three-dimensional planning.

A patient with a typical carcinoid tumor in the left main bronchus underwent robotic left main bronchial sleeve resection through a left transthoracic approach.

Gen Thorac Cardiovasc SurgAug 14, 2026Read case
Clinical ResearchOncology (Medical)

Daily low-dose carboplatin or weekly carboplatin plus nab-paclitaxel for concurrent chemoradiotherapy in older patients with locally advanced non-small cell lung cancer (JCOG1914): A randomized phase 3 trial.

This randomized phase 3 trial evaluated daily low-dose carboplatin versus weekly carboplatin plus nab-paclitaxel in patients aged ≥75 years with locally advanced non-small cell lung cancer (LA-NSCLC).

Lung CancerAug 14, 2026Read summary
Clinical ResearchOncology (Medical)

Adjuvant oxaliplatin with S-1 (SOX) versus S-1 for stage II-III gastric cancer (CAPITAL): A randomized, open-label, phase 3 trial.

The CAPITAL trial, a multicenter, randomized phase 3 study, evaluated the efficacy of adjuvant oxaliplatin plus S-1 (SOX) versus S-1 alone in patients with stage II-III gastric or gastroesophageal junction…

MedAug 14, 2026Read summary
Clinical ResearchGeneral Surgery

Textbook outcome in esophagogastric oncological surgery and long-term survival - A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether achieving Textbook Outcome (TO), a composite measure of surgical quality, was associated with long-term survival after esophageal or gastric cancer surgery.

Eur J Surg OncolAug 14, 2026Read summary
Case ReportEndocrinology

Molecular stability overrides size in giant pediatric pheochromocytoma.

A 16-year-old female presented with severe hypertension and hyperglycemia, initially misdiagnosed with essential hypertension and type 2 diabetes.

J Pediatr Endocrinol MetabAug 14, 2026Read case
Clinical ResearchOncology (Medical)

Effects of non-pharmacological interventions on chemotherapy-induced taste alterations among cancer patients: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed non-pharmacological interventions for chemotherapy-induced taste alterations in people with cancer.

Int J Nurs StudAug 14, 2026Read summary
Clinical ResearchNuclear Medicine

Comparison of lesion detection rates between FAPI PET/CT and 18 F-FDG PET/CT in hepatocellular carcinoma: a systematic review and meta-analysis of head-to-head studies.

This systematic review and meta-analysis compared lesion detection by fibroblast activation protein inhibitor (FAPI) PET/CT and 18F-FDG PET/CT in hepatocellular carcinoma (HCC), using head-to-head studies.

Jpn J RadiolAug 14, 2026Read summary
Clinical ResearchGastroenterology

Cryoablation versus radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of cryoablation (CA) versus radiofrequency ablation (RFA) in treating hepatocellular carcinoma (HCC).

Int J HyperthermiaAug 13, 2026Read summary
Case ReportOncology (Medical)

Atezolizumab, lurbinectedin, tarlatamab, and FOLFIRNOX in a patient with metastatic small cell carcinoma of the anal canal: A case report and review of the literature.

A 60-year-old woman with metastatic small cell carcinoma of the anal canal was treated with a regimen based on small cell lung cancer protocols.

Semin OncolAug 13, 2026Read case

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