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2000 articles
August 202624
Early red blood cell transfusion strategy in septic shock among patients with cancer: the TRANSPORT randomized controlled trial.
The TRANSPORT trial investigated red blood cell transfusion strategies in 187 cancer patients with septic shock. Patients were assigned to either a liberal or restrictive transfusion strategy.
Second umbilical cord blood transplantation for relapsed adverse-risk acute myeloid leukemia patient with near-homozygous HLA haplotypes.
A patient with adverse-risk acute myeloid leukemia (AML) and near-homozygous HLA haplotypes underwent double units unrelated umbilical cord blood transplantation (dUCBT) twice.
Vaginal natural orifice transluminal endoscopic surgery versus conventional laparoscopy for sentinel lymph node mapping in early-stage endometrial cancer: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared vaginal natural orifice transluminal endoscopic surgery (vNOTES) with conventional laparoscopy for sentinel lymph node mapping in early-stage endometrial…
Prognostic Value of Androgen Receptor (AR) Gene Alterations Detected in Circulating Tumor DNA (ctDNA) in Patients With Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the prognostic significance of androgen receptor (AR) gene alterations in circulating tumor DNA (ctDNA) among patients with metastatic castration-resistant prostate…
The clinical value of adding immune checkpoint inhibitors to radiotherapy for cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the clinical benefits of adding immune checkpoint inhibitors (ICIs) to radiotherapy in cancer patients, analyzing 15 randomized clinical trials with 7947 participants.
Addressing fear of breast cancer recurrence through process-oriented hypnosis.
A young woman with a history of breast cancer experienced severe fear of cancer recurrence following a double-mastectomy. This fear significantly impacted her daily life despite successful treatment.
Chemotherapy resistance and risk stratification in gestational trophoblastic neoplasia: A systematic review and network meta-analysis.
This systematic review and network meta-analysis examined pretreatment predictors of chemotherapy resistance and compared resistance across regimens in gestational trophoblastic neoplasia (GTN).
Intravascular Large B-Cell Lymphoma After Kidney Transplantation: A Rare Form of Post-Transplant Lymphoproliferative Disorder.
A Japanese man in his 60s developed intravascular large B-cell lymphoma (IVLBCL) 4.5 years after kidney transplantation, presenting with general fatigue and loss of appetite.
Pediatric Gastric GIST With SDHA Truncation Despite Retained SDHB Staining: A Case Report.
A 14-year-old boy presented with a gastric GIST, which was positive for KIT and DOG1. Genetic analysis revealed a truncating variant in the SDHA gene, indicating SDH deficiency.
Under pressure: A phase I pilot trial evaluating pressurised intraperitoneal aerosol chemotherapy with oxaliplatin in resectable high-risk gastric cancer.
This prospective, single-centre, non-randomised, open-label phase I pilot trial assessed the safety and feasibility of adding pressurised intraperitoneal aerosol chemotherapy with oxaliplatin (PIPAC-O+) to perioperative…
Cutibacterium avidum caused a liver abscess after transarterial chemoembolization for hepatocellular carcinoma.
An 83-year-old man developed a liver abscess following transarterial chemoembolization for recurrent hepatocellular carcinoma, presenting with fever 10 days post-procedure.
Predictors of Enrolment in a Transoral Surgical Trial for HPV-Related Oropharyngeal Carcinoma.
This Phase III clinical trial investigated factors influencing enrolment in a transoral surgical trial for HPV-related oropharyngeal carcinoma. Among 51 eligible patients, 29 (57%) chose to participate.
Immune checkpoint inhibitors in cancer patients with pre-existing autoimmune disease: Comparative safety and efficacy in a registered systematic review.
This registered systematic review and restricted meta-analysis compared immune checkpoint inhibitor (ICI) safety and efficacy in cancer patients with versus without pre-existing autoimmune disease (AID).
Incremental risk of high-grade adverse events with immune checkpoint inhibitors with or without poly(adenosine diphosphate-ribose) polymerase inhibitors in first-line treatment of advanced endometrial cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled six randomized phase II or III trials involving 2,995 patients with advanced or recurrent endometrial cancer receiving first-line platinum-based chemotherapy.
Circulating MicroRNAs as Diagnostic and Prognostic Biomarkers for Neuroblastoma: A Systematic Review and Exploratory Re-analysis.
This systematic review and exploratory re-analysis assessed circulating microRNAs as diagnostic and prognostic biomarkers in patients with neuroblastoma. Nine studies involving 385 patients were included.
Biomarker-based risk stratification for predicting late recurrence and benefit of extended endocrine therapy: A secondary analysis of the IDEAL trial.
This secondary analysis of the Phase III IDEAL trial evaluated the CanAssist Breast (CAB) biomarker for predicting late recurrences in 3052 hormone receptor-positive, HER2-negative early breast cancer patients.
Impact of propofol-based vs. volatile-based anaesthesia on survival and recurrence after cancer surgery: a systematic review and meta-analysis of randomised trials.
This systematic review and meta-analysis assessed randomised trials comparing propofol-based with volatile-based anaesthesia in adults undergoing curative cancer surgery.
Pineoblastoma in a 5-Year-Old Male: A Case Report and Review of Literature.
A 5-year-old male presented with symptoms indicative of raised intracranial pressure. Imaging studies identified a tumor in the pineal region, which was confirmed as pineoblastoma through histopathological evaluation.
Postdiagnostic Red Meat, Poultry, and Egg Intake and Risk of Prostate Cancer Progression and Mortality: A Systematic Review.
This systematic review assessed prospective cohort evidence on postdiagnostic red meat, poultry, and egg intake and outcomes among men with prostate cancer. Six cohorts including more than 10,000 men were eligible.
Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy.
A 3-month-old male presented with fever, lymphadenopathy, and macrocephaly due to multiple dural-based masses causing obstructive hydrocephalus.
Anthracycline-Free Neoadjuvant Therapy With Nab-Paclitaxel and Carboplatin in Non-Luminal Breast Cancer: A Single-Arm Clinical Trial.
NEOPATH was a prospective, single-centre, single-arm clinical trial evaluating neoadjuvant nab-paclitaxel plus carboplatin in patients with stage II–III triple-negative or HER2-positive breast cancer; HER2-positive…
False-Positive 123I-MIBG Uptake Attributable to Contralateral Erector Spinae Muscle Hypertrophy Following Retroperitoneal Surgery in a Child With Neuroblastoma.
A 5-year-old girl with high-risk neuroblastoma underwent ¹²³I-MIBG SPECT/CT after resection of a right adrenal tumor; baseline imaging showed no abnormal uptake.
The Potential Role of 99m Tc-FAPI SPECT/CT in the Staging of Mucinous Appendiceal Adenocarcinoma.
We present a 55‑year‑old woman with adnexal masses and elevated CEA. Malignancy workup, adnexal biopsy, and intraoperative assessment revealed the appendix as the primary site, with pathology confirming mucinous…
Neoadjuvant Immunotherapy in Localized dMMR/MSI-H Colon Cancer: A Systematic Review of Pathological Response and Surgical Outcomes.
This systematic review assessed prospective interventional studies of neoadjuvant immune checkpoint inhibition in adults with localized, non-metastatic dMMR/MSI-H colon cancer. Six studies were included.
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