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1382 articles

June 20266

Clinical ResearchPediatrics

Randomised, Multicentre Clinical Trial Found That Hypertonic Saline Did Not Reduce the Length of Stay of Hospitalised Patients With Acute Bronchiolitis.

This randomized controlled trial evaluated the effectiveness of nebulised hypertonic saline compared to normal saline in 181 hospitalized infants with acute bronchiolitis.

Acta PaediatrJun 3, 2026Read summary
Clinical ResearchPediatrics

Venous thromboembolism in children with lower limb fractures: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed venous thromboembolism (VTE), risk factors, mortality, and pharmacological prophylaxis in children with lower limb fractures.

InjuryJun 3, 2026Read summary
Case ReportPediatrics

A Case Series of Vaccine-strain Reactivation Varicella Zoster in Two Pediatric Patients Presenting With Headache and Rash.

Two immunocompetent children who had received routine varicella vaccination presented with headache and rash. Cerebrospinal fluid testing confirmed varicella zoster virus meningitis and identified the Oka vaccine strain.

Pediatr Infect Dis JJun 3, 2026Read case
Case ReportInfectious Diseases

First Case of Congenital Toxoplasmosis After Maternal Reinfection in Colombia: Serotyping Evidence of Reinfection by Different Strains.

An immunocompetent woman with prior Toxoplasma IgG positivity later had both IgG and IgM detected four months before pregnancy.

Pediatr Infect Dis JJun 3, 2026Read case
Case ReportDermatology

Infantile tinea faciei caused by Trichophyton indotineae successfully treated with topical ketoconazole: A case report.

A 5-month-old Vietnamese infant presented with tinea faciei caused by Trichophyton indotineae, likely transmitted from the mother.

Diagn Microbiol Infect DisJun 2, 2026Read case
Case ReportGastroenterology

Sudden Acute Liver Failure in Citrullinemia Type 1: An Argument for Earlier Liver Transplantation?

This report details a case of a child with citrullinemia type 1 who presented with sudden acute liver failure. Despite medical management, the child experienced recurrent hepatic decompensations, ultimately…

J PediatrJun 2, 2026Read case

May 202618

Clinical ResearchNeurology

Prevalence of drug-resistant epilepsy in low and middle income countries: a systematic review and meta-analysis.

This systematic review and meta-analysis estimated the prevalence of drug-resistant epilepsy (DRE) in low- and middle-income countries (LMICs).

Epilepsy BehavMay 31, 2026Read summary
Case ReportPediatrics

Percc1-Associated Congenital Diarrhea and Enteropathy: Description of a Novel Variant.

An infant diagnosed at 2 months of age had congenital diarrhea and enteropathy associated with a novel homozygous PERCC1 variant, c.337 del, in exon 2.

Pediatr Dev PatholMay 31, 2026Read case
Clinical ResearchPsychiatryOpen access

Safety and tolerance of oral ketamine: A systematic review.

This systematic review assessed the safety and tolerability of oral ketamine across various clinical populations, including adults and children.

Psychiatry Clin NeurosciMay 30, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Lethal Suspected DICER1 Syndrome Spectrum in Neonate with CPAM Type IV/Type I PPB, Genitourinary Abnormalities, and CNS Embryonal Tumor with Multilayered Rosettes.

A premature neonate, aged 8 days, had been diagnosed prenatally with renal and cystic lung abnormalities and died from severe respiratory dysfunction.

Pediatr Dev PatholMay 30, 2026Read case
Case ReportPediatrics

Non-24-Hour Sleep-Wake Disorder in Children and Adolescents: A Case Series.

A single-center retrospective series described six sighted children and adolescents diagnosed with non-24-hour sleep-wake disorder.

Behav Sleep MedMay 30, 2026Read case
Case ReportPediatricsOpen access

Subperiosteal abscess in pediatric acute osteomyelitis: ultrasound-guided percutaneous aspiration in three cases.

Three pediatric patients with acute osteomyelitis developed subperiosteal abscesses, traditionally treated with surgical drainage.

Skeletal RadiolMay 29, 2026Read case
Case ReportInfectious Diseases

Congenital syphilis in neonates: Persistent diagnostic and treatment challenges in resource-limited settings.

Five neonates born to mothers with reactive syphilis serology were identified at a tertiary care center in northern India. All infants were asymptomatic at birth, but only two mothers received adequate treatment.

Trop DoctMay 29, 2026Read case
Case ReportInfectious Diseases

Case report:Maribavir for refractory CMV infection in 2 pediatric HSCT recipients.

Two pediatric patients with refractory cytomegalovirus (CMV) infection post-hematopoietic stem cell transplantation (HSCT) were treated with maribavir after conventional therapies failed.

Diagn Microbiol Infect DisMay 28, 2026Read case
Case ReportInfectious Diseases

Successful use of outpatient parenteral antimicrobial therapy (OPAT) aztreonam-avibactam in a pediatric case of an infectious pseudoarthrosis caused by NDM-producing Klebsiella pneumoniae and Pseudomonas aeruginosa.

A 9-year-old girl with war-related trauma developed infectious pseudoarthrosis of the distal tibia due to NDM-producing Klebsiella pneumoniae and Pseudomonas aeruginosa.

Int J Infect DisMay 28, 2026Read case
Case ReportOtolaryngology (ENT)

Bioabsorbable Stenting in a Case of Severe Pediatric Posterior Glottic Stenosis.

A 2-year-old girl with transverse myelitis and neuromuscular respiratory failure developed posterior glottic stenosis after multiple intubations.

Ann Otol Rhinol LaryngolMay 28, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Thyroid Myofibroma in a Child With Turner Syndrome: Integrated Cytologic, Histopathologic, and Molecular Characterization.

A 9-year-old girl with Turner syndrome and a history of parotid myofibroblastic proliferation presented with a solitary thyroid nodule.

Pediatr Dev PatholMay 28, 2026Read case
Clinical ResearchPediatricsOpen access

Comparison of safety and immunogenicity between high-dose and low-dose quadrivalent influenza vaccines in children aged 6-35 months in China: A randomized, double-blind clinical study.

This randomized, double-blind clinical study evaluated the safety and immunogenicity of high-dose versus low-dose quadrivalent influenza vaccines in 3,000 children aged 6-35 months in China.

Hum Vaccin ImmunotherMay 27, 2026Read summary
Clinical ResearchPediatrics

Sustained and indirect effects of PCV10 reduced-dose schedules on pneumococcal carriage in Viet Nam: a long-term follow-up of a cluster-randomised controlled trial.

This long-term follow-up of a cluster-randomised controlled trial in Nha Trang, Viet Nam, assessed the effects of reduced-dose PCV10 schedules on pneumococcal carriage 5.5 years post-vaccination.

Lancet Infect DisMay 27, 2026Read summary
Clinical ResearchAllergy & Immunology

Exploratory pilot trial of a multicomponent immunonutritional supplement in children with allergic asthma and rhinitis: The INAPRA study.

The INAPRA study was a multicenter, randomized, double-blind, placebo-controlled pilot trial investigating a multicomponent immunonutritional supplement in 40 children aged 5-12 with allergic asthma and rhinitis.

Int ImmunopharmacolMay 27, 2026Read summary
Case ReportInfectious Diseases

Diphtheritic polyneuropathy: Not so uncommon.

This report details four cases of diphtheritic polyneuropathy (DP) identified during a limited outbreak of diphtheria, affecting children who had received their infant vaccinations.

Trop DoctMay 27, 2026Read case
Case ReportPediatrics

Postnatal Care-associated Echovirus 11 Infection in Malaysia: Severe Disease With Variable Outcomes.

Five neonates aged 2–9 days in Kuala Lumpur had laboratory-confirmed echovirus 11 (E11) infection. Four developed multiorgan failure, particularly liver dysfunction, and required intensive care; two died.

Pediatr Infect Dis JMay 27, 2026Read case
Clinical ResearchPediatricsOpen access

Immunogenicity and safety of an investigational quadrivalent measles, mumps, rubella, and varicella vaccine in children aged 4-6 years: A phase II, randomized, multi-country trial.

This phase II, randomized, multi-country trial evaluated the immunogenicity and safety of an investigational quadrivalent measles, mumps, rubella, and varicella vaccine (MMRVNS) in healthy children aged 4-6 years.

Hum Vaccin ImmunotherMay 26, 2026Read summary
Clinical ResearchUrology

Comparative Analysis of Ureteral Reimplantation and Dextranomer/Hyaluronic Acid Injection Between Two Centers With Systematic Review and Meta-Analysis.

This study compared dextranomer/hyaluronic acid (Dx/HA) injection and ureteral reimplantation in children under 18 with recurrent UTIs.

J UrolMay 26, 2026Read summary

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