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2000 articles
August 202624
Diet and risk of bladder cancer: a systematic review of epidemiological evidence.
This systematic review synthesised prospective cohort evidence on dietary exposures and urothelial cancer incidence. It included 32 cohorts with 2 277 677 participants; only one study specifically examined upper tract…
Prognostic value of CD103+ tumor-infiltrating lymphocytes in bladder cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic significance of CD103+ tumor-infiltrating lymphocytes in bladder cancer, focusing on muscle-invasive and metastatic cases.
Antitumor activity of scorpion venom-derived peptides: A meta-analysis of preclinical studies.
This meta-analysis evaluated the antitumor effects of scorpion venom-derived peptides (SVDPs) across various cancer types in preclinical studies.
BK Polyomavirus-Associated Carcinoma In Situ of the Renal Allograft: Balancing Oncologic Control and Graft Preservation.
A female renal transplant recipient in her 60s presented with biopsy-proven carcinoma in situ (CIS) of the urothelium within her renal allograft, following a history of BK polyomavirus nephropathy.
CEUS-Guided Core Needle Biopsy Reduces Underestimation in Breast Lesions: A Prospective Randomized Study.
This single-centre prospective randomised controlled trial compared contrast-enhanced ultrasound (CEUS)-guided with conventional ultrasound-guided core needle biopsy in 340 patients undergoing breast lesion biopsy.
Complete Resection of Simultaneous Hepatic and Pulmonary Metastases from Colorectal Cancer in the Era of Modern Systemic and Surgical Therapies: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the feasibility and outcomes of resecting simultaneous hepatic and pulmonary metastases from metastatic colorectal cancer.
Whole-pelvic Versus Prostate-only Radiotherapy in Clinically Node-negative High-Risk Localised Prostate Cancer: A Systematic Review and Meta-analysis with Reconstructed Individual-patient Data.
This systematic review and meta-analysis pooled five phase III randomised trials (5172 patients) comparing elective whole-pelvic radiotherapy (WPRT) with prostate-only radiotherapy (PORT) for clinically node-negative…
Older adults with resectable gastric cancer undergoing perioperative chemotherapy or preoperative chemoradiotherapy plus perioperative chemotherapy: A secondary analysis of the AGITG TOPGEAR phase III trial.
This secondary analysis of the AGITG TOPGEAR phase III trial evaluated older adults (≥70 years) with resectable gastric cancer undergoing perioperative chemotherapy or chemoradiotherapy.
First-line pyrotinib plus apatinib in advanced non-small cell lung cancer harboring HER2 mutations or amplification: a phase II trial.
This phase II trial evaluated the efficacy of pyrotinib plus apatinib in treatment-naïve patients with advanced non-small cell lung cancer (NSCLC) harboring HER2 mutations or amplification.
Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36.
This phase I clinical trial evaluated the immunogenicity of 20 µg AAV2-like particles displaying HPV L2 residues in 20 healthy subjects.
Atezolizumab with or without tiragolumab in unresectable esophageal squamous-cell carcinoma following definitive concurrent chemoradiotherapy (SKYSCRAPER-07): a randomised, phase III study.
SKYSCRAPER-07 was a global, randomised, placebo-controlled phase III trial of 760 adults with unresectable esophageal squamous-cell carcinoma after definitive concurrent chemoradiotherapy.
Geriatric Assessment and Cancer Survival Prediction by the Vulnerable Elders Survey-13 Screening Tool: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the Vulnerable Elders Survey-13 (VES-13) tool's diagnostic and prognostic value in cancer patients aged 65 and older.
Soft tissue reconstruction techniques after musculoskeletal tumor resection: A systematic review of gastrocnemius flap, free flap, local flap, and orthoplastic reconstruction.
This PRISMA-guided systematic review examined soft tissue reconstruction after musculoskeletal tumor resection, searching six databases through 30 June 2026.
Five-year outcomes of perioperative pembrolizumab for early-stage non-small-cell lung cancer from the randomized KEYNOTE-671 study.
This phase III, multicentre randomised trial assessed perioperative pembrolizumab plus platinum-doublet chemotherapy and surgery in previously untreated, resectable stage II, IIIA, or IIIB (N2) non-small-cell lung…
Multifocal Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type, Presenting on Face and Chest: Complete Remission With R-CHOP.
A 79-year-old woman developed rapidly enlarging erythematous-to-violaceous tumors and plaques on her face, chest, left upper arm, and upper back.
Hidden Malignancy: Predominantly InSitu Porocarcinoma Arising in a Poroma.
A 79-year-old woman presented with a well-circumscribed exophytic mass on her right calcaneal region, which had been enlarging over two years.
Prognostic value of inflammation-immunity-nutrition score in cancer patients: a meta-analysis.
This meta-analysis evaluated the prognostic value of the inflammation-immunity-nutrition score (IINS) in cancer patients, analyzing data from 3,950 participants across eight studies.
Pathologic Complete Response (pCR) Rate and Predictors of Response to Taxane, Trastuzumab, and Pertuzumab in HER2‑Positive Breast Cancer: Secondary Analyses of EA1181/CompassHER2 pCR.
This single-arm phase II trial evaluated neoadjuvant taxane, trastuzumab, and pertuzumab (THP) followed by surgery in patients with clinical stage II/IIIa HER2-positive breast cancer.
Positive Intraoperative Frozen Section during Surgery for Junctional and Gastric Cancer: Should We Re-Resect? A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed whether re-excision after a positive intraoperative frozen section is associated with improved overall survival in patients undergoing curative-intent…
Effect of renin-angiotensin system inhibitors on survival in glioma patients: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of renin-angiotensin system inhibitors (RASIs) on survival in glioma patients, analyzing data from seven studies involving 2660 patients.
Prognostic significance of NLRP-3 expression in solid cancers: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prognostic significance of NLRP-3 expression in patients with solid cancers.
Prophylactic Hyperthermic Intraperitoneal Chemotherapy in Locally Advanced Colorectal Cancer: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) for locally advanced colorectal cancer.
Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy.
A 70-year-old man with metastatic melanoma developed a distinct pleomorphic rhabdomyosarcoma during treatment with immune checkpoint inhibitors, including pembrolizumab and ipilimumab.
Multimodal management of refractory gastrointestinal bleeding in myeloma-associated acquired von Willebrand syndrome: a role for emicizumab prophylaxis.
A 72-year-old woman with IgG κ multiple myeloma, acquired von Willebrand syndrome, and gastrointestinal angiodysplasia had recurrent life-threatening bleeding despite factor concentrates, intravenous immunoglobulin…
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