Trending archive
Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.
2000 articles
September 20264
PiggyBac-Engineered Membrane-Bound IL7 TILs Combined with Anti-PD-1 Antibody Demonstrates Efficacy in Recurrent Ovarian Cancer: A First-in-Human Phase I Trial.
This first-in-human phase I trial evaluated the safety and efficacy of GC203, a genetically modified tumor-infiltrating lymphocyte (TIL) product, in 18 heavily pretreated patients with recurrent ovarian cancer.
Etomidate combined with TAPB in ovarian cancer surgery: A controlled study on hemodynamics and immune response.
This randomized controlled trial evaluated the effects of etomidate combined with transversus abdominis plane block (TAPB) on hemodynamics and immune response in 80 patients undergoing ovarian cancer surgery.
High-dose radiotherapy in patients with high-risk prostate cancers treated with long-term androgen deprivation therapy (GETUG AFU 18): a randomised, phase 3 trial.
This multicenter, open-label, randomized phase 3 trial evaluated the impact of dose-escalated radiotherapy (80 Gy) versus standard radiotherapy (70 Gy) on progression-free survival in 505 men with high-risk prostate…
SHR-A2102, a nectin-4 directed antibody-drug conjugate, in patients with pretreated advanced solid tumours: a multicentre, single-arm, phase 1 trial.
This multicentre, single-arm phase 1 trial evaluated the safety and preliminary activity of SHR-A2102, a nectin-4 directed antibody-drug conjugate, in 395 patients with pretreated advanced solid tumours.
August 202620
Long-Term Oncologic Outcomes of Neoadjuvant Tumor-Directed Immunotherapy (PROSTVAC) Before Radical Prostatectomy for Localized Prostate Cancer: A Secondary Analysis of a Neoadjuvant Trial.
This secondary analysis of a phase II neoadjuvant trial assessed long-term oncologic outcomes in 26 patients with localized prostate cancer who received PROSTVAC before radical prostatectomy.
Indocyanine green-guided sentinel node navigation surgery in early gastric cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed the feasibility and diagnostic performance of indocyanine green (ICG)-guided sentinel node navigation surgery (SNNS) in selected patients with early gastric cancer.
Phase II Study of Posttransplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After HLA-Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion Cohort.
This prospective, multicenter phase II study evaluated posttransplant cyclophosphamide (PTCy)-based graft-versus-host disease prophylaxis in adults receiving peripheral blood stem cell transplantation from…
Efficacy and safety of bispecific antibodies versus other antitumor therapies in solid tumors: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of bispecific antibodies (BsAbs) in treating solid tumors, involving 3,505 patients across 9 studies.
Impact of intensive care unit admission on the resumption of treatment in patients with cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the resumption of anticancer treatment in adult patients with cancer after unplanned ICU admission.
Efficacy, safety, and biomarker analysis of neoadjuvant camrelizumab plus apatinib as a chemotherapy-free strategy for early-stage triple-negative breast cancer: a phase II study.
This phase II clinical trial evaluated the efficacy and safety of neoadjuvant camrelizumab plus apatinib in patients with early-stage triple-negative breast cancer (TNBC) and high tumor-infiltrating lymphocytes (TILs).
Impact of patient positioning on the efficacy and safety of doxycycline pleurodesis in malignant pleural effusion: a pilot randomized trial.
This pilot randomized trial evaluated the efficacy and safety of doxycycline pleurodesis in 40 patients with malignant pleural effusion, comparing a standard rotation protocol to a non-rotation approach.
Calcitonin-negative medullary thyroid carcinoma in a young adult.
A young woman in her early 20s presented with a thyroid nodule and normal serum calcitonin levels, which typically indicate the absence of medullary thyroid carcinoma (MTC).
The management of complex patients with inoperable stage III NSCLC: practical lessons from case-based discussion.
This article presents four case studies of patients with inoperable stage III non-small cell lung cancer discussed at a UK academic webinar.
18 F-fluciclovine PET Imaging of Non-PSMA Expressing High-risk Primary Prostate Cancer.
A 67-year-old man with rising PSA and a palpable prostate lesion had a large PI-RADS 5 lesion on MRI. Biopsy showed high-grade prostate cancer (Gleason score 9 [4+5], grade group 5).
CASPR2 antibody-associated neurological syndrome after PD-1 inhibitor treatment (tislelizumab) in a patient with lung adenocarcinoma: A case report and literature review.
A 46-year-old woman with advanced non-small cell lung cancer developed cerebellar, cognitive, and autonomic symptoms one week after her second tislelizumab cycle.
Exercise prehabilitation in head and neck cancer patients proposed for definitive chemoradiotherapy: The FIT4TREAT randomized controlled trial.
The FIT4TREAT randomized controlled trial evaluated the impact of exercise prehabilitation (EP) on functional capacity in patients with head and neck cancer scheduled for definitive chemoradiotherapy.
Pelvic floor muscle training for erectile function in men undergoing radical prostatectomy: a systematic review of randomized controlled trials.
This systematic review evaluated the effectiveness of pelvic floor muscle training (PFMT) on erectile function (EF) in men post-radical prostatectomy, analyzing twelve randomized controlled trials.
Biological determinism and the stage-dependent role of surgical approach in gallbladder cancer: A 20-year cohort study and meta-analysis.
This retrospective cohort study of 416 patients who underwent gallbladder cancer surgery at a national tertiary centre from 2003 to 2022, combined with a systematic review and meta-analysis of surgical approach in…
Radiation Associated Undifferentiated Pleomorphic Sarcoma of the Neck 2 Decades After External Beam Radiation for Medullary Thyroid Carcinoma: A Case Report and Literature Review.
A 54-year-old man developed a painless neck mass 22 years after receiving 59.4 Gy radiation for medullary thyroid carcinoma.
Effect of Vutrisiran According to Baseline Tafamidis Use in Transthyretin Amyloidosis With Cardiomyopathy: Insights From HELIOS-B.
This randomized controlled trial evaluated the effects of vutrisiran in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), stratified by baseline tafamidis use.
Subcentimeter Ileal Neuroendocrine Tumor Resection for Obscure Gastrointestinal Bleeding Followed by Pacemaker-Treated Sick Sinus Syndrome: A Case Report.
A 72-year-old man presented with melena and abdominal discomfort, with prior endoscopies yielding no diagnosis. Multiphase computed tomographic enterography identified an 11×8 mm enhancing nodule in the distal small…
Prognostic significance of systemic immunoinflammatory biomarkers and pathological features in clear cell renal cell carcinoma: a multicenter study.
This multicenter retrospective study evaluated systemic immunoinflammatory biomarkers and pathological features to develop a prognostic model for overall survival (OS) in clear cell renal cell carcinoma (ccRCC).
Prognostic models and predictors of recurrence in resectable colorectal liver metastases: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed prognostic models and recurrence predictors after curative-intent locoregional treatment of colorectal liver metastases.
Liver transplant allocation by milan criteria may exclude eligible HCC patients without survival benefit - a post-hoc analysis of the SiLVER study.
This post-hoc analysis of the SiLVER Study evaluated the Milan criteria for liver transplant eligibility in 485 patients with hepatocellular carcinoma (HCC).
Showing the most recent matches. Add a word or a date to reach older ones.
Stay updated for free
Get the 3 most interesting publications in one specialty each week.
Weekly email. Unsubscribe anytime.
Want this personalized?
Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.
- Your specialties
- Your filters and thresholds
- Clinical Research + Case Reports, tuned separately
- Automatic weekly delivery
- Audio and text
Prefer listening? Personalized audio digests are available with Pro.