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1357 articles
November 202624
Diagnostic yield and early outcomes of radical prostatectomy without prior histopathologic diagnosis: a single-arm systematic review and meta-analysis.
This single-arm systematic review and random-effects meta-analysis assessed radical prostatectomy without prior histopathologic confirmation in adult men with high clinical suspicion of clinically significant prostate…
Comparative Efficacy of Different Biologic Agents on Radiographic Progression in Patients with Rheumatoid Arthritis: A Network Meta-Analysis.
This Bayesian random-effects network meta-analysis compared six biologic DMARD classes for radiographic progression in rheumatoid arthritis, using randomized controlled trials and change in modified Total Sharp Score…
Effectiveness of guided internet-delivered cognitive behavioral therapy for insomnia in autistic adults (i-Sleep Autism): a randomized controlled trial.
This randomized controlled trial evaluated a 5-week, guided internet-delivered cognitive behavioral therapy intervention adapted for autistic adults with insomnia.
Oliceridine vs Sufentanil Combined With Ondansetron for Postoperative Nausea and Vomiting and QTc Interval in Hysteroscopic Surgery: A Prospective Randomized Controlled Study.
This prospective, randomized, double-blind controlled study compared oliceridine plus ondansetron with sufentanil plus ondansetron in 62 patients undergoing non-intubated hysteroscopic surgery under general anesthesia.
Testing the Impact of the #Chatsafe Intervention on Young People's Ability to Communicate Safely About Suicide on Social Media: A Randomized Controlled Trial.
This randomized controlled trial evaluated whether #chatsafe social media content improved safe online communication about suicide among young people aged 16–25 years.
Outcomes with Catheter-Directed Thrombolysis versus Mechanical Thrombectomy for Patients with Intermediate/High Risk Pulmonary Embolism: A Meta-Analysis of 24,090 Patients.
This meta-analysis compared catheter-directed thrombolysis (CDT) with mechanical thrombectomy (MT) in patients with intermediate- or high-risk pulmonary embolism treated with catheter-based therapies.
Left bundle branch area vs biventricular pacing for cardiac resynchronization therapy: the LEFT-BUNDLE-CRT trial.
The multicentre, randomized, non-inferiority LEFT-BUNDLE-CRT trial compared left-bundle branch area pacing (LBBAP) with biventricular pacing (BiVP) for cardiac resynchronization in patients with guideline-based…
A nurse-coordinated intervention programme vs standard of care after an acute coronary syndrome: the ALLEPRE trial.
The multicentre, pragmatic, randomized ALLEPRE trial compared a nurse-coordinated prevention programme with hospital standard care in patients recovering from acute coronary syndrome.
Machine Learning Models for Glycemic Prediction in Type 1 and Type 2 Diabetes: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed machine-learning models predicting glucose values or glycemic events in people with type 1, type 2, mixed, or unclear diabetes.
Sequencing trastuzumab deruxtecan and sacituzumab govitecan in metastatic breast cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether treatment order affects outcomes when patients with metastatic breast cancer receive both trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG).
Sex Differences in Blood Pressure Dynamics and Outcomes After Endovascular Thrombectomy.
This exploratory secondary analysis of the multicenter, open-label, blinded-end-point ENCHANTED2/MT randomized trial examined sex differences in blood pressure (BP) and outcomes among adults with acute ischemic stroke…
Dose-specific effects of caffeinated chewing gum on reactive blocking timing, jump mechanics, and neuromuscular responses after volleyball-specific fatigue in elite female volleyball players.
This randomized, double-blind, placebo-controlled crossover study examined caffeinated chewing gum in 15 elite female volleyball players after a volleyball-specific repeated-blocking fatigue protocol.
Short-term outcomes of the hinotori versus da Vinci robotic surgical systems in colorectal cancer surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis compared short-term perioperative outcomes of hinotori and da Vinci robotic systems in colorectal cancer surgery.
Single-port robotic thoracic surgery: a systematic review and meta-analysis of comparative outcomes versus multiport robotic surgery and uniportal VATS.
This systematic review and meta-analysis compared single-port robotic-assisted thoracic surgery (SP-RATS) with multiport robotic surgery (MP-RATS) and uniportal video-assisted thoracoscopic surgery (uVATS).
Molecular Diagnostics and Clinicopathologic Spectrum of Kinase Fusion-Positive Spindle Cell Neoplasms of the Oral and Maxillofacial Region: A Systematic Review and Pooled Patient-Level Analysis.
This systematic review and pooled patient-level analysis characterized kinase fusion-positive spindle cell neoplasms of the oral and maxillofacial region using published reports.
Cardiac Damage and Clinical Outcomes in Symptomatic Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
This post hoc subanalysis of the multicentre, randomised LANDMARK trial examined whether updated echocardiographic cardiac-damage stages stratified outcomes after transcatheter aortic valve replacement (TAVR) in…
Prevalence and Consequences of Guideline-Directed Indications for Aortic Valve Replacement in the EARLY TAVR Trial.
This analysis of the multicenter randomized EARLY TAVR trial examined how often patients with asymptomatic severe aortic stenosis had ACC/AHA Class II indications for aortic valve replacement (AVR), and whether these…
Evening amber-lensed glasses in combination with a prescribed wake time advance circadian timing in adolescents with delayed sleep-wake phase disorder.
This 3-week randomized controlled trial tested evening amber-lensed glasses plus a prescribed stable wake time in adolescents aged 14.3–18.1 years with delayed sleep-wake phase disorder (DSWPD).
The pen-and-paper tube figures mental rotation task for patients with trauma-related disorders: a randomized controlled trial.
This single-centre, single-blind randomized controlled trial compared a one-session pen-and-paper Tube figures imagery-competing task intervention with a Wikipedia control in 40 patients with trauma-related disorders.
Prolonged exposure, eye movement desensitization and reprocessing therapy, and cognitive restructuring versus waiting-list for individuals with PTSD and psychosis (RE.PROCESS): A multicenter, four-arm, assessor-masked, superiority randomized controlled trial.
The multicenter, assessor-masked RE.PROCESS randomized controlled trial compared Prolonged Exposure (PE), eye movement desensitization and reprocessing (EMDR), and Cognitive Restructuring (CR), each alongside usual…
Surgical outcomes and functional morbidity after retrosigmoid/retrocondylar and midline suboccipital approaches for foramen magnum meningiomas: a single-arm meta-analysis.
This PRISMA-guided systematic review and single-arm meta-analysis assessed surgical control and functional morbidity after posterior or posterolateral approaches for foramen magnum meningiomas.
Efficacy and safety of the cladribine, idarubicin, and cytarabine regimen for treating acute myeloid leukemia: a systematic review and single-arm meta-analysis.
This systematic review and single-arm meta-analysis assessed the efficacy and safety of cladribine, idarubicin, and cytarabine (CIA) for acute myeloid leukemia (AML), separating newly diagnosed (ND) from…
Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): a randomized controlled trial.
This multicentre randomized controlled trial tested whether app-based cognitive behavioural therapy (CBT) reduced persistent postsurgical pain in adults with operatively treated extremity fractures at 11 hospitals in…
Dose-dense neoadjuvant bi-weekly nab-paclitaxel followed by epirubicin-cyclophosphamide versus bi-weekly docetaxel followed by epirubicin-cyclophosphamide in patients with HR+/HER2- early breast cancer: a multicentre, randomised, phase III trial.
This multicentre, randomised phase III trial at three hospitals in China compared dose-dense neoadjuvant nab-paclitaxel with docetaxel, each followed by epirubicin-cyclophosphamide, in patients with early HR+/HER2−…
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