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2000 articles
September 202624
First-line camrelizumab plus chemotherapy followed by camrelizumab-apatinib maintenance for ES-SCLC: a single-arm phase II study.
This single-arm phase II trial evaluated first-line camrelizumab plus platinum-etoposide followed by camrelizumab-apatinib maintenance in treatment-naïve patients with extensive-stage small-cell lung cancer.
Positive Effect of Methylphenidate for Cancer-Related Cognitive Impairment: A Pilot Randomized Trial.
This pilot randomized, double-blind, placebo-controlled trial assessed methylphenidate (MPH) for cancer-related cognitive impairment in women who had completed breast cancer treatment at least six months earlier and had…
Clinically silent pheochromocytoma presenting as an adrenal incidentaloma: the importance of biochemical evaluation.
A woman in her late 70s presented with a 5 cm left adrenal mass found incidentally during imaging for unrelated issues. Despite well-controlled hypertension and no classic symptoms of catecholamine excess, biochemical…
Vesicocutaneous fistula secondary to invasive bladder squamous cell carcinoma: an unusual initial presentation.
An elderly man presented with urinary leakage from an abdominal wound and signs of sepsis, following a progressive suprapubic swelling that ruptured.
Reversible exacerbation of parkinsonism during epirubicin-cyclophosphamide chemotherapy in a patient with PTEN hamartoma tumor syndrome and young-onset Parkinson's disease.
A patient with a germline PTEN variant and young-onset Parkinson's disease developed severe exacerbations of parkinsonism during epirubicin-cyclophosphamide chemotherapy for bilateral breast cancer.
Natural products targeting the molecular pathology of salivary gland mucoepidermoid carcinoma: A systematic review of In vitro studies.
This systematic review evaluated the antitumor effects of natural products on human mucoepidermoid carcinoma cell lines. Fourteen in vitro studies were included, revealing that these interventions impaired cell…
Safety and antitumor activity of the first-in-class EGFR-HER3 bispecific antibody-drug conjugate iza-bren (BL-B01D1) in patients with pretreated locally advanced or metastatic breast cancer: a phase Ib study.
This multicenter phase Ib study evaluated the safety and antitumor activity of iza-bren, an EGFR-HER3 bispecific antibody-drug conjugate, in 162 patients with heavily pretreated locally advanced or metastatic breast…
Effectiveness of Topical Huzhang Sanhuang with Standard Nursing for Chemotherapy-Induced Phlebitis: Randomized Controlled Study.
This randomized controlled trial assessed the effectiveness of topical Huzhang Sanhuang (HZSH) combined with standard nursing care in 94 hospitalized patients with chemotherapy-induced phlebitis (CIP).
Multidisciplinary management of an older adult with vascular Ehlers-Danlos syndrome and multiple autoimmune comorbidities.
An early 60s female with vascular Ehlers-Danlos syndrome (vEDS) presented with extensive comorbidities, including systemic lupus erythematosus and rheumatoid arthritis.
Prognostic impact of high-grade transformation in low-grade B-cell lymphomas: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled overall-survival data from 38 datasets in 35 studies comparing high-grade transformation (HGT) of low-grade B-cell lymphoma with non-transformed low-grade lymphoma or de…
Pseudo-negative serum protein electrophoresis due to IgM aggregation in a patient with Waldenström macroglobulinemia: A case report.
A 79-year-old male presented with 10 months of anemia and bilateral lower limb and testicular edema. Following serological testing, serum protein electrophoresis, and genetic analysis, he was diagnosed with Waldenström…
Successful treatment of a large-sized triple-negative breast cancer: A case report.
A 38-year-old female with stage IV triple-negative breast cancer (TNBC) experienced tumor recurrence and rapid progression one year post-surgery.
Managing malignant recurrent pericardial effusion in a palliative patient with bleomycin sclerotherapy: A case report from Bangladesh.
A 50-year-old male with advanced lung cancer presented with recurrent malignant pericardial effusion, causing significant dyspnea and chest pain.
Activin pathway inhibition and rapid progression of malignancy in pulmonary arterial hypertension: A case series and hypothesis.
The report describes malignancies occurring in patients with pulmonary arterial hypertension (PAH) treated with sotatercept, an activin-pathway inhibitor.
Pregnancy in a patient with metastatic functioning midgut neuroendocrine tumor receiving lanreotide after peptide receptor radionuclide therapy.
A pregnant patient with a metastatic neuroendocrine tumor of the ileocecal valve and carcinoid syndrome was treated with lanreotide after undergoing peptide receptor radionuclide therapy and debulking surgery.
Assessment of the role and effectiveness of nurse-led multimodal intervention in the rehabilitation of dysphagia in patients with brain tumors.
This randomized controlled trial evaluated the effectiveness of a nurse-led multimodal intervention for dysphagia rehabilitation in 120 brain tumor patients.
ENCERT: A Multisite Phase 1 Trial Using Everolimus in Combination With Nelarabine, Cyclophosphamide, and Etoposide in Relapsed T-Cell Lymphoblastic Leukemia/Lymphoma.
This multisite Phase 1 trial assessed the safety and efficacy of everolimus combined with nelarabine, cyclophosphamide, and etoposide in children and young adults with relapsed/refractory T-cell acute lymphoblastic…
Genetic basis of pancreatic steatosis: a systematic review of comparison between African and non-African populations.
This systematic review examined genetic factors associated with pancreatic steatosis in African versus non-African populations, analyzing data from over 120,000 participants.
Triplet chemotherapy with Gemcitabine, Nab-paclitaxel, and S-1 achieves high response and conversion rates in advanced pancreatic cancer: A multicenter phase II study (GeNeS1S trial).
This multicenter phase II study evaluated the efficacy and safety of triplet chemotherapy with Gemcitabine, Nab-paclitaxel, and S-1 in 30 patients with advanced pancreatic cancer.
Impact of center-level protocol adherence on neoadjuvant treatment outcome in pancreatic ductal adenocarcinoma.
This multicenter phase III trial analyzed the impact of chemotherapy dose reductions and protocol adherence on event-free survival (EFS) in 260 patients with resectable and borderline resectable pancreatic ductal…
Biomarker-defined benefit from FLOT plus nivolumab in metastatic gastroesophageal cancer: Extended follow-up and immune-inflammatory markers of the phase II IKF-AIO-moonlight trial.
This extended follow-up and subgroup analysis of the multicentre phase II AIO-STO-0417 trial examined FLOT plus nivolumab in patients with advanced gastroesophageal adenocarcinoma.
177 Lu-FAPI-2286 Radioligand Therapy in Refractory Scalp Melanoma.
A 66-year-old man with inoperable scalp melanoma that had not responded to immunotherapy was assessed for 177Lu-DOTATATE therapy.
Validation of the newly introduced Deauville score 5a for patients treated for advanced-stage classic Hodgkin lymphoma.
This randomized controlled trial evaluated the prognostic value of the newly defined Deauville score 5a in patients with advanced-stage classical Hodgkin lymphoma (AS-cHL) after two cycles of treatment.
Improved quality of life and prolonged survival with add-on homeopathic treatment in patients with non-small cell lung cancer: a prospective, randomized, placebo-controlled, double-blind, three-arm, multicenter study.
This multicenter, randomized, placebo-controlled trial evaluated the effects of add-on homeopathic treatment on quality of life (QoL) and survival in 98 patients with stage IV non-small cell lung cancer (NSCLC).
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