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702 articles

October 202624

Clinical ResearchOrthopedic Surgery

Efficacy and cost effectiveness of high volume injections with and without corticosteroid compared with sham for midportion Achilles tendinopathy (Inject trial): randomised controlled trial.

The Inject trial was a single-centre, participant- and assessor-masked, three-arm randomised controlled trial in 192 adults with midportion Achilles tendinopathy.

BMJOct 28, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Short-term effects of myofascial release with therapist-mediated transcutaneous electrical nerve stimulation in adolescent idiopathic scoliosis: an exploratory randomized controlled trial .

This assessor-blinded, exploratory randomized controlled trial evaluated short-term myofascial release with therapist-mediated transcutaneous electrical nerve stimulation (MFR-TENS) in 27 adolescents with idiopathic…

Childs Nerv SystOct 28, 2026Read summary
Clinical ResearchAnesthesiology

Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.

This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…

Acta Anaesthesiol ScandOct 27, 2026Read summary
Clinical ResearchOrthopedic Surgery

Comparative effectiveness of three splints for rehabilitation after finger flexor tendon repair (FIRST): randomised controlled trial.

The FIRST pragmatic, multicentre randomised trial compared forearm-based long, Manchester short, and relative motion flexion mini splints for rehabilitation after primary zone 1 or 2 finger flexor tendon repair.

BMJOct 27, 2026Read summary
Clinical ResearchOrthopedic Surgery

Evaluating treatment efficacy for Iliotibial Band Syndrome: A comparison of combined foam rolling and stretching with strengthening exercises versus strengthening alone in athletes.

This randomized controlled trial compared strengthening alone with strengthening plus foam rolling and stretching in 20 athletes with confirmed iliotibial band syndrome.

PLoS OneOct 27, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Cost-effectiveness of recommended interventions for managing low back pain: A systematic review.

This systematic review assessed the cost-effectiveness of guideline-recommended interventions for non-specific low back pain compared with usual care.

PLoS MedOct 27, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Efficacy and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis pooled randomized controlled trials comparing topical with intravenous tranexamic acid (TXA) in patients undergoing primary total knee arthroplasty. Eleven trials were included.

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Virtual reality surgical simulator training of residents and early-career surgeons for pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis included six randomized controlled trials comparing virtual reality (VR) simulation with conventional teaching for pedicle screw placement training in residents and early-career…

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Closed percutaneous reduction versus mini-open sinus tarsi approach for fixation of displaced intra-articular calcaneal fractures: a systematic review and meta-analysis.

This systematic review and meta-analysis compared closed percutaneous reduction (PR) with the mini-open sinus tarsi approach (STA) for acute displaced intra-articular calcaneal fractures.

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchNeurosurgery

Intra-wound Vancomycin Powder for Surgical Site Infection Prophylaxis in Spinal Surgery: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis examined intra-wound vancomycin powder at closure versus no powder in patients undergoing spinal surgery.

J Vis ExpOct 27, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of Adding Esketamine to Patient-Controlled Intravenous Analgesia on Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether adding esketamine to postoperative patient-controlled intravenous analgesia (PCIA) reduces rebound pain after interscalene brachial plexus block in patients undergoing…

Drug Des Devel TherOct 27, 2026Read summary
Clinical ResearchOrthopedic Surgery

Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .

This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchRadiology (Diagnostic)Open access

A systematic review of the spectrum of magnetic resonance imaging features of degenerative thoracic myelopathy.

This PRISMA-guided systematic review synthesised evidence on MRI features of degenerative thoracic myelopathy (DTM) and their clinical significance.

Neurosurg RevOct 26, 2026Read summary
Case ReportAnesthesiologyOpen access

Sequential Lidocaine and Liposomal Bupivacaine for Popliteal Sciatic Nerve Block in Foot and Ankle Surgery: A Randomized Controlled Trial.

In foot and ankle surgery, prolonged analgesia after popliteal sciatic nerve block (PSNB) may be accompanied by delayed motor recovery.

Drug Des Devel TherOct 26, 2026Read case
Clinical ResearchOrthopedic Surgery

Clinical Pathway Management for Platelet-Rich Plasma Therapy in Kellgren-Lawrence Grade I and II Knee Osteoarthritis: A Prospective, Multicenter, Double-Blind Randomized Controlled Trial.

This multicenter, double-blind randomized controlled trial compared a standardized platelet-rich plasma (PRP) pathway with physician-directed conventional PRP care in patients with Kellgren-Lawrence grade I or II knee…

Am J Sports MedOct 26, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Measurement Properties of Hand-Held Dynamometry for Ankle Strength Assessment: A COSMIN-Based Systematic Review and Meta-Analysis.

This COSMIN-based systematic review and meta-analysis assessed handheld dynamometry (HHD) for measuring isometric ankle muscle strength in healthy individuals.

Musculoskeletal CareOct 25, 2026Read summary
Case ReportNeurosurgeryOpen access

Posterior Realignment and Anterior Column Reconstruction of Thoracic Spondyloptosis Using Intraoperative CT and Navigation: Case Report and Review of the Literature.

An 18-year-old man presented after a motorcycle collision with complete paraplegia and a T4 sensory level (AIS A). CT showed T5–T6 spondyloptosis with translation, rotation, vertebral comminution, and complete…

Int Med Case Rep JOct 24, 2026Read case
Case ReportOrthopedic SurgeryOpen access

Integrated tendon repair and staged skin grafting for a severe forearm degloving injury: A case report from a low-resource setting.

A 21-year-old right-handed man presented two hours after a road traffic collision with extensive degloving of the right forearm, wrist, and dorsal thumb.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Effects of grip strengthening combined with scapular stabilization exercise on shoulder muscle strength and functional outcomes in individuals with subacromial pain syndrome: A randomized controlled trial.

This randomized controlled trial compared scapular stabilization exercise with the same exercise combined with grip strengthening in 36 individuals with subacromial pain syndrome (SAPS).

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

A case report of pulmonary embolism following endoscopic cervical discectomy in an elderly patient with cervical disc herniation.

A 65-year-old woman with cervical disc herniation, right arm pain, and multiple comorbidities underwent posterior percutaneous endoscopic cervical discectomy after conservative treatment failed.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Effects of sensorimotor training combined with short foot exercise on knee and ankle gait kinematics in individuals with flatfoot: A preliminary study.

This preliminary randomized controlled trial compared six weeks of sensorimotor training plus short-foot exercises with sensorimotor training alone in 32 asymptomatic young adults with flexible flatfoot.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportAnesthesiologyOpen access

Opioid-Free versus Opioid-Based Anesthesia for Quality of Recovery After Knee Arthroscopy: A Randomized Non-Inferiority Trial.

We determined whether dexmedetomidine- and esketamine-based opioid-free anesthesia (OFA) was non-inferior to opioid-based anesthesia (OA) for 24-hour Quality of Recovery-15 (QoR-15) after elective knee arthroscopy with…

Drug Des Devel TherOct 23, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Platelet-rich plasma for knee osteoarthritis: a systematic review and meta-analysis of structural outcomes.

This systematic review and meta-analysis assessed imaging-based structural outcomes after platelet-rich plasma (PRP) treatment in people with knee osteoarthritis.

Arch Orthop Trauma SurgOct 22, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Mid-term clinical outcomes and isokinetic performance after primary total knee arthroplasty within a modified ERAS protocol: a single-blinded randomized controlled trial.

This prospective, single-blinded randomized controlled trial compared a modified Enhanced Recovery After Surgery (ERAS) protocol with conventional perioperative care in 58 patients undergoing primary total knee…

BMC Musculoskelet DisordOct 22, 2026Read summary

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