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1382 articles
July 202624
Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341-Associated Cancer.
A lethal round-cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent.
Smoking cessation interventions for parents of children with chronic disease: A systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated smoking cessation interventions for parents of children with chronic diseases, analyzing ten randomized controlled trials with 3758 participants.
Precision of neuromuscular monitoring in paediatric patients: a randomised prospective agreement study of kinemyography and electromyography.
This randomized controlled trial evaluated the precision of kinemyography versus electromyography for neuromuscular monitoring in children under 5 years old.
Recurrent KCNN4 p.Ser314Pro variant in a child with Gardos channelopathy: a 6-year follow-up.
A child with Gardos channelopathy due to a recurrent KCNN4 p.Ser314Pro variant was followed for 6 years. The patient maintained a stable baseline but experienced hemolytic crises triggered by infections and exacerbated…
Association of maternal prepregnancy malnutrition with offspring growth trajectories: a secondary data analysis of the Women First Trial.
This secondary data analysis from the Women First Trial examined the impact of maternal prepregnancy malnutrition on offspring growth in 2228 mother-child pairs across several countries.
Early-onset juvenile Paget disease associated with a homozygous intronic TNFRSF11B variant: a 2-year follow-up.
A 2-month-old infant presented with severe irritability and pain on gentle movement, femoral swelling, and persistent hyperphosphatasemia.
Clinical Reasoning: A Toddler With Heat Stroke.
A 17-month-old boy presented with febrile seizures and encephalopathy after being exposed to hot weather in a poorly ventilated car.
Dexamethasone-Free Antiemetic Prophylaxis for Children and Adolescents Receiving Highly Emetogenic Chemotherapy: A Multicenter, Phase III, Noninferiority Trial (CIVIC POD).
The CIVIC POD trial evaluated the efficacy of olanzapine versus dexamethasone for preventing chemotherapy-induced nausea and vomiting in children aged 4-18 receiving highly emetogenic chemotherapy.
Neuroimaging anxious children and adolescents before and after cognitive behavioral therapy: a systematic review.
This systematic review examined neuroimaging studies of youths under 19 with anxiety disorders undergoing cognitive behavioral therapy (CBT).
Genetic susceptibility to thrombotic microangiopathy in a 10-month-old patient with SMA type 1: a caveat for gene therapy eligibility.
A 10-month-old girl with spinal muscular atrophy type 1 was initially deemed eligible for gene therapy with onasemnogene abeparvovec.
The effect of mandala coloring on pain, stress, and sleep quality in children hospitalized in a burn unit: A randomized controlled trial.
This randomized controlled trial assessed the impact of mandala coloring on pain, stress, and sleep quality in 40 children aged 7-12 hospitalized in a burn unit.
Otopathology of Pediatric Acute Tuberculous Meningitis-Case Series.
This case series presents three temporal bones from infants who succumbed to acute tuberculous meningitis (TBM). Pathological examination revealed significant inner ear damage, including cochlear fibrosis, atrophy of…
Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence.
This systematic review examined how puberty, emotion regulation, and body dissatisfaction relate in young people aged 6–18. Searches of five databases identified 103 studies for data extraction from 3,658 records.
Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes.
This Phase II/III clinical trial analyzed the efficacy of intravenous plasminogen concentrate in 17 pediatric patients with Type 1 plasminogen deficiency (PLGD-1).
Outcomes of Congenital Neuroblastoma With Placental Metastases: A Systematic Review.
This systematic review examined outcomes of congenital neuroblastoma with placental metastases, analyzing 16 articles and identifying 19 cases.
Evaluating a culturally adapted question prompt list to improve end-of-life communication among indonesian migrant caregivers: A randomized controlled trial with qualitative insights.
This randomized controlled trial evaluated a culturally adapted Question Prompt List (QPL) aimed at improving end-of-life communication among 60 Indonesian caregivers in Taiwan.
Brain Abscess as the Initial Manifestation of Hereditary Hemorrhagic Telangiectasia in a Child.
Brain abscess secondary to pulmonary arteriovenous malformation is rare in children and may be the first manifestation of hereditary hemorrhagic telangiectasia (HHT).
A systematic review of paediatric-specific risk factors for nosocomial infections in paediatric intensive care units, 2005-2024.
This systematic review analyzed 24 observational studies involving 74,960 children in pediatric intensive care units (PICUs) to identify risk factors for nosocomial infections (NIs).
Antibiotic resistance in the paediatric population in Pakistan (1996-2025): a systematic review and meta-analysis.
This systematic review and meta-analysis examined antibiotic resistance in the pediatric population of Pakistan from 1996 to 2025.
Efficacy of different lighting schemes on refractive development and choroidal thickness in school-age children.
This randomized controlled trial examined the effects of a one-year high-illuminance crystal pure full-spectrum lighting scheme on refractive development in 198 school-aged children (6-10 years).
Effect of Antenatal Breastfeeding Counseling on Early Initiation and Exclusive Breastfeeding in India: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed antenatal breastfeeding counseling and education in India, including randomized, quasi-experimental, comparative, and other intervention studies.
Long-Term Clinical Outcomes of Tisagenlecleucel in Pediatric and Young Adult Patients With Relapsed/Refractory ALL.
This 5-year analysis of the global phase II ELIANA trial assessed long-term outcomes after a single tisagenlecleucel infusion in 79 children and young adults with relapsed or refractory B-cell acute lymphoblastic…
Systematic review of pediatric abdominal aortic aneurysms.
This PRISMA-compliant systematic review examined causes, presentation, management, and outcomes of abdominal aortic aneurysms in patients aged 18 years or younger, drawing on eligible case reports and case series.
Skeletal coccidioidomycosis: an atypical pediatric presentation.
A previously healthy 12-year-old presented with 1.5 months of progressive left pelvic pain, night sweats, and weight loss, without respiratory symptoms.
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