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1357 articles
October 202624
Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .
This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.
A Short Evidence-Based, Belief-Focused Educational Video Improves Back Pain Beliefs but Not Lifting Behaviour in Healthy Office Workers: An Exploratory Randomised Controlled Trial.
This assessor-blind exploratory randomised controlled trial assigned 50 healthy office workers to a brief video about back pain beliefs and management or an anatomy-video control.
Low-dose ketamine modulates brain entropy in treatment-resistant depression: Results from two neuroimaging clinical trials.
This analysis of resting-state functional MRI data from two randomized clinical trials examined whether low-dose ketamine changes brain entropy in patients with treatment-resistant depression.
From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.
This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.
Does the "switch the plane" strategy improve outcomes? Anterior vs. posterior repair for recurrence after prior inguinal hernia repair: a systematic review and meta-analysis.
This systematic review and meta-analysis examined outcomes of recurrent unilateral inguinal hernia repair by operative plane, including comparative studies of posterior versus repeat anterior repair after prior anterior…
Berberine improves diabetic foot ulcer healing after tibial transverse osteotomy by inhibiting the PDGF-B/PDGFRβ signaling pathway .
This prospective, single-centre, randomized, placebo-controlled trial evaluated local berberine injections added to tibial transverse osteotomy (TTO) in patients with Wagner grade 2–4 diabetic foot ulcers.
The combination of simethicone and N-acetylcysteine in lidocaine ice popsicle compared with lidocaine ice popsicle alone in patients undergoing unsedated esophagogastroduodenoscopy: A prospective double-blind randomized controlled trial.
This single-centre, prospective, double-blind randomised controlled trial compared a lidocaine ice popsicle containing simethicone and N-acetylcysteine (NAC) with a conventional lidocaine popsicle in 374 adults…
Gut relief revisited: plecanatide in chronic idiopathic constipation and irritable bowel syndrome with constipation - a systematic review and meta-analysis with GRADE assessment.
This systematic review and meta-analysis with GRADE assessment pooled randomized controlled trials comparing plecanatide with placebo in people with chronic idiopathic constipation (CIC) or irritable bowel syndrome with…
Are intervention effects on fruit and vegetable intake maintained after 48 months of follow-up? A randomised controlled community trial.
This randomised controlled community trial assessed whether increases in fruit and vegetable (FV) intake after a 7-month transtheoretical model-based intervention were maintained among users of a Brazilian primary…
Clinical Pathway Management for Platelet-Rich Plasma Therapy in Kellgren-Lawrence Grade I and II Knee Osteoarthritis: A Prospective, Multicenter, Double-Blind Randomized Controlled Trial.
This multicenter, double-blind randomized controlled trial compared a standardized platelet-rich plasma (PRP) pathway with physician-directed conventional PRP care in patients with Kellgren-Lawrence grade I or II knee…
Safety of low lipoprotein(a) levels: the FOURIER trial.
This analysis of the randomized, multicentre FOURIER trial examined associations between lipoprotein(a) [Lp(a)] levels and safety outcomes in patients with stable atherosclerotic cardiovascular disease receiving…
The Impact of Conversational Turn-Taking on Vocabulary Size in Toddlers With Developmental Delays Using Augmentative and Alternative Communication.
This secondary analysis of archival data from two studies examined conversational turn-taking and vocabulary during a 12-week language intervention in 109 parent–child dyads involving children with developmental delays.
Evaluating gain and loss-framed mobile messaging to improve maternal health service uptake: A cluster randomized controlled trial in Jimma, Ethiopia.
This three-arm cluster-randomized controlled trial assessed whether gain- or loss-framed SMS messaging improved maternal health service use among 588 pregnant women in Jimma Zone, Ethiopia.
Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.
This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.
A systematic review of the spectrum of magnetic resonance imaging features of degenerative thoracic myelopathy.
This PRISMA-guided systematic review synthesised evidence on MRI features of degenerative thoracic myelopathy (DTM) and their clinical significance.
Music-based interventions for people with kidney failure undergoing haemodialysis.
This Cochrane systematic review and meta-analysis assessed randomised trials of music-based interventions in people with kidney failure receiving haemodialysis.
Family Resilience and Coping in Disasters, Pandemics, and Large-Scale Crises: A Systematic Review.
This systematic review synthesized peer-reviewed research on family resilience and coping during disasters, pandemics, and sustained adversity.
Adjunctive topical mitomycin C during endoscopic dilation for pediatric caustic esophageal stricture: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis assessed topical mitomycin C (MMC) added to endoscopic dilation for caustic esophageal stricture in children.
Dose-Response Effects of Exercise Training on Circulating Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-analysis of Randomised Controlled Trials.
This systematic review and meta-analysis pooled randomised controlled trials comparing chronic exercise with non-exercising controls to assess circulating brain-derived neurotrophic factor (BDNF).
Does Portable Voice Amplification Improve Vocal Outcomes in Elementary School Teachers? Evidence From Aerodynamic, Acoustic, and Self-Reported Measures.
This randomized controlled trial evaluated portable classroom voice amplification plus vocal hygiene versus vocal hygiene alone in elementary school teachers with voice complaints or normal voices.
Individual Effects of Angiotensin II Receptor Blockers on Major Adverse Cardiovascular Events: A Systematic Review and Network Meta-Analysis.
This systematic review and random-effects network meta-analysis compared angiotensin II receptor blockers (ARBs) for cardiovascular outcomes in randomized trials not primarily designed to study heart failure.
Effectiveness of Implantable Cardioverter-Defibrillator Therapy for Primary Prevention in Patients with Nonischemic Heart Failure with Reduced Ejection Fraction.
This rapid systematic review and meta-analysis assessed primary-prevention implantable cardioverter-defibrillator (ICD) therapy in patients with nonischemic heart failure with reduced ejection fraction, drawing on 18…
Exposure to antidepressant and antipsychotic medicines in pregnant women and risk of gestational diabetes: a systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis pooled observational studies of gestational diabetes mellitus (GDM) among pregnant women exposed to antidepressants or antipsychotics.
Lithium in the Prevention of Postpartum Recurrence of Mood Disorders: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed postpartum mood-disorder recurrence among women with bipolar I or II disorder, comparing those who received prophylactic lithium with those who did not.
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