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1357 articles
October 202624
Erector spinae plane block added to intercostal nerve block versus intercostal nerve block alone for postoperative analgesia in video-assisted thoracoscopic surgery: A randomized controlled trial.
This prospective, randomized controlled trial compared surgical intercostal nerve block (INB) alone with INB plus single-injection erector spinae plane block (ESPB) in 60 adults undergoing elective three-port…
Exposure to natural disasters and vaccination indicators: a systematic review and directions for future research.
This systematic review examined peer-reviewed research on exposure to natural disasters and vaccination indicators, including vaccine administration, coverage, and rates.
Cost-effectiveness of recommended interventions for managing low back pain: A systematic review.
This systematic review assessed the cost-effectiveness of guideline-recommended interventions for non-specific low back pain compared with usual care.
Diagnostic accuracy of high-sensitivity point-of-care troponin assays in emergency department for patients presenting with chest pain: a systematic review.
This systematic review assessed the diagnostic accuracy of four commercially available high-sensitivity point-of-care troponin assays in adults presenting to emergency departments with chest pain suggestive of acute…
STRONG prehabilitation before elective ventral hernia repair: Learnings from recruitment challenges in a randomized controlled trial.
The multicentre, parallel-group STRONG-Hernia randomised controlled trial assessed intensive lifestyle prehabilitation before elective ventral hernia repair in adults with at least one risky smoking, nutrition, alcohol…
Evaluating treatment efficacy for Iliotibial Band Syndrome: A comparison of combined foam rolling and stretching with strengthening exercises versus strengthening alone in athletes.
This randomized controlled trial compared strengthening alone with strengthening plus foam rolling and stretching in 20 athletes with confirmed iliotibial band syndrome.
Efficacy and safety of Lianhua Qingwen versus oseltamivir in children with influenza: a multicenter, randomized, double-blind, positive parallel-controlled study.
This multicenter, randomized, double-blind, positive-controlled trial compared Lianhua Qingwen (LHQW) with oseltamivir in children aged 3–14 years with influenza.
Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial.
This randomized controlled trial compared handgrip and knee-extension isometric training with control in 67 adults with controlled hypertension receiving antihypertensive medication.
Efficacy and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled randomized controlled trials comparing topical with intravenous tranexamic acid (TXA) in patients undergoing primary total knee arthroplasty. Eleven trials were included.
Intra-wound Vancomycin Powder for Surgical Site Infection Prophylaxis in Spinal Surgery: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis examined intra-wound vancomycin powder at closure versus no powder in patients undergoing spinal surgery.
Effectiveness of Wrist-Worn Wearable-Guided Cardiac Rehabilitation Delivered Through Fully Remote or Hybrid Programs in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis assessed randomized trials of wrist-worn wearable-guided cardiac rehabilitation delivered remotely or in hybrid formats during phase II or III rehabilitation for adults with…
Zamtocabtagene autoleucel, a tandem CD20-CD19-directed CAR T-cell therapy, for second line treatment of large B-cell lymphoma in patients ineligible for transplantation (DALY 2-EU): primary analysis of an open-label, multicentre, randomised phase 2 study.
DALY 2-EU was an open-label, multicentre, randomised phase 2 trial comparing tandem CD20-CD19-directed zamtocabtagene autoleucel (zamto-cel) with R-GemOx in adults with second-line relapsed or refractory large B-cell…
Rare and Novel Hepatitis C Virus Genotype Subtypes and Response to Sofosbuvir/Velpatasvir in A5360 (MINMON) Clinical Trial.
This analysis of samples from the multicountry ACTG A5360 (MINMON) clinical trial characterized rare and novel hepatitis C virus (HCV) subtypes and assessed baseline resistance-associated substitutions and response to…
Comparative Effects of Different Mind-Body Exercises on Lung Function, Exercise Capacity, and Quality of Life in Adults with Stable Chronic Obstructive Pulmonary Disease: A Bayesian Network Meta-Analysis.
This Bayesian network meta-analysis assessed mind-body exercises (MBEs) for lung function, exercise capacity, and quality of life in adults with stable COPD.
An Individual Meta-Analysis of Psychological Treatments for Mood and Personality Disorders Using the Severity Diagnostic System of ICD-11.
This individual patient meta-analysis examined whether ICD-11 personality-disorder severity was associated with short-term outcomes in 1,384 patients from four randomised trials of psychological treatments, mainly…
Association of Screen Time With Physical and Mental Health in University Students: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined screen-time duration and physical and mental health outcomes in university students aged 17 years or older.
Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.
This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.
Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.
This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.
Outdoor risky play and health-related outcomes in children aged 3-12 years: A mixed-methods systematic review.
This mixed-methods systematic review synthesised evidence on outdoor risky play and health outcomes in children aged 3–12 years. It included 74 studies: 48 quantitative, 19 qualitative and 7 mixed-methods.
Ruzaltatug rezetecan versus chemotherapy for EGFR-mutated advanced non-small-cell lung cancer progressing after EGFR tyrosine kinase inhibitor therapy (HERON-Lung01): interim analysis of a randomised, open-label, phase 3 trial in China.
HERON-Lung01 was a randomised, open-label, phase 3 trial at 62 sites in China comparing the HER3-directed antibody-drug conjugate ruzaltatug rezetecan with platinum-pemetrexed chemotherapy in patients with EGFR-mutated…
Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.
This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.
Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.
This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.
Safety and Effectiveness of a Novel Laser-Based Intravascular Lithotripsy System for Coronary Calcium: FRACTURE Study.
FRACTURE was a prospective, multicenter, single-arm clinical trial evaluating a laser- and optic-based quad-emitter intravascular lithotripsy system in patients with severely calcified de novo coronary lesions.
Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.
This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.
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