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1382 articles
August 202624
Peroxisomal disorder associated with ACOX1 gain-of-function mimicking neuroinflammatory disease.
A 6-year-old girl presented with motor delay, ichthyosiform eczema, gait disturbance, pain, weakness, areflexia, hypomimia, and hearing loss.
A skeletally immature patient with Diamond-Blackfan anemia with Deferoxamine induced bone dysplasia: An analysis on diffusion tensor imaging.
A 9-year-old boy with Diamond-Blackfan anemia receiving chronic deferoxamine chelation presented with bilateral genu valgum.
Impact of structured exercise-based regimen on frailty in pediatric cirrhosis: A randomized controlled trial.
This randomized controlled pilot trial assessed a structured exercise regimen in children aged 9–18 years with cirrhotic liver disease and frailty, comparing exercise plus standard medical therapy (SMT) with SMT alone.
Efficacy and safety of nasal saline irrigation for allergic rhinitis in children and adolescents: A systematic review and meta-analysis with GRADE assessment.
This systematic review and meta-analysis evaluated the efficacy and safety of nasal saline irrigation (NSI) for allergic rhinitis in children and adolescents.
The efficacy of oral montelukast versus intranasal fluticasone furoate in reducing the severity of pediatric sleep-disordered breathing: A randomized clinical trial.
This randomized clinical trial evaluated the efficacy of oral montelukast versus intranasal fluticasone furoate in reducing sleep-disordered breathing (SDB) severity in children aged 2-15 with adenotonsillar…
Adversity profiles among Canadian families: A secondary data analysis of a randomized controlled trial of the Family Check-Up®.
This randomized controlled trial analyzed data from 206 Canadian families to explore the effectiveness of the Family Check-Up® (FCU®) across different adversity profiles.
Examining Sex-Based Inequities in Pediatric Sports Medicine Research: A Systematic Review.
This Level IV systematic review examined sex-based inclusion in original pediatric sports medicine research published from 2020 to 2024 in 12 interdisciplinary journals.
Generalized Laser-Induced Erythema Under General Anesthesia in Infants: A Case Series.
During Q-switched ruby laser treatment under general anesthesia, three infants—two with nevus of Ota and one with ectopic Mongolian spots—developed rapidly spreading generalized erythema.
Feedback-enhanced electronic monitoring for asthma inhaler adherence: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed feedback-enhanced electronic inhaler monitoring versus standard care in people with asthma.
Toothbrush Design and Developmental Characteristics Influencing Plaque Removal in 7-Year-Old Children: A Randomized Crossover Trial.
This single-blind, randomized three-period crossover trial compared conventional manual, triple-headed manual, and rechargeable powered toothbrushes in 60 typically developing 7-year-old children.
Endoscopic techniques in the treatment of vesicoureteral junction obstruction in children with primary obstructive megaureter: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed endoscopic treatment of vesicoureteral junction obstruction in children with primary obstructive megaureter.
Pharmacogenetic hypersensitivity to somatropin in a child with severe growth hormone deficiency and MC4R p.V166I variant.
A boy with multiple pituitary hormone deficiencies and severe growth hormone deficiency began somatropin at 57 months of age, when his height and growth velocity were low. He carried a heterozygous MC4R p.V166I variant.
"Accessible and Acceptable" Drop-In Mental Health Services for Children With Long-Term Conditions: A Mixed-Methods Exploratory Analysis of Integrated Services From a Health Equity Perspective.
This mixed-methods exploratory analysis evaluated drop-in mental health services for children with long-term conditions across six pediatric healthcare settings.
Oral Rhabdomyomatous Hamartoma in a Paediatric Patient: Case Report a Rare Lesion.
An 8-year-old boy presented with a submucosal nodule on the left lateral border of the tongue. A dermoid cyst was initially suspected, but histopathological examination showed thick, interlacing bundles of skeletal…
Association between clinician team structure and continuous pulse oximetry overuse among infants hospitalized with bronchiolitis: An Eliminating Monitor Overuse Trial substudy.
This secondary analysis of the multicenter Eliminating Monitor Overuse randomized trial examined whether frontline clinician type was associated with continuous pulse oximetry (cSpO₂) overuse among hospitalized children…
The impact of corticosteroid therapy on clinical outcomes in paediatric deep neck space infections: A meta-analysis.
This meta-analysis examined the impact of corticosteroid therapy on clinical outcomes in pediatric patients with deep neck space infections (DNSIs).
Comparison of Iodinated Contrast Doses Based on Total Body Weight and Lean Body Weight in Pediatric Patients: Impact on Image Quality and Contrast Exposure.
This randomized controlled trial evaluated iodinated contrast dosing in 66 pediatric patients (ages 0-16) undergoing abdominal CT, comparing lean body weight (LBW) and total body weight (TBW) dosing protocols.
Spectrum of Neurofascin-155 Autoimmune Nodopathy in a Pediatric Cohort: A Single Center Experience.
This single-center pediatric case series described four patients with anti-neurofascin-155 autoimmune nodopathy. All had distal weakness and sensory loss; three also had tremor and sensory ataxia.
Clinical Profile, Electrophysiology, and Short-Term Outcomes of Pediatric-Onset Autoimmune Nodopathy-A Case Series.
The report describes three children with autoimmune nodopathy associated with antibodies to neurofascin 140, alone or with neurofascin 186.
Effectiveness of the Bladder Stimulation Technique for Infant Urine Collection in the Pediatric Emergency Department: A Randomized Controlled Trial.
This randomized controlled trial compared bladder stimulation with standard positioning for urine collection in 64 nontoilet-trained infants aged 1 to 12 months.
Clinical and Genetic Profile of One Molecularly Confirmed and One Clinically Suspected Case of LZTR1 -Related Noonan Syndrome.
Two unrelated female pediatric patients were evaluated for LZTR1-related Noonan syndrome. The first patient exhibited isolated short stature and subtle dysmorphic features, with a confirmed heterozygous pathogenic…
Effects of Esketamine on Emergence Delirium in Children Undergoing Sevoflurane Anesthesia: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis.
This systematic review and meta-analysis evaluated the efficacy of esketamine in preventing emergence delirium in 916 pediatric patients undergoing sevoflurane anesthesia.
Pediatric Cluster Headache Beyond Diagnostic Criteria: A Case Series and Review of Treatment Response.
The report describes four children—three boys and one girl—diagnosed with cluster headache, a disorder characterized by brief, unilateral pain around the eye with autonomic symptoms.
Severe atopic dermatitis and growth failure associated with a STAT5B gene mutation in a 7-month-old infant.
A 7-month-old boy with no significant perinatal history was referred for a skin condition present for 5 months and severe growth retardation, including low weight for height.
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