Trending archive
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1382 articles
August 202624
Three Generations of X-Linked Hypophosphataemia: The Inter-generational Impact of Burosumab Across the Lifespan.
This case report describes three generations of a family affected by X-linked hypophosphataemia (XLH), each receiving burosumab therapy at different life stages.
Systematic Review of the Relationship Between the Presence and Quality of Sidewalks and Children's Physical Health.
This systematic review examined associations between sidewalk availability or quality and physical health outcomes in children.
Noncoronary sinus of Valsalva aneurysm with rupture into the right atrium.
A 13-year-old boy died suddenly after vomiting, his only initial symptom. Forensic autopsy identified a noncoronary sinus of Valsalva aneurysm that had ruptured into the right atrium, causing acute circulatory…
The optimal stent-strategy in paediatric pyeloplasty: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared internal JJ stents, external transanastomotic stents and stentless repair after Anderson-Hynes pyeloplasty in children with pelvi-ureteric junction obstruction.
Deep versus moderate hypothermia in pediatric cardiac surgery: Systematic review and meta-analysis of early postoperative outcomes.
This systematic review and meta-analysis compared deep hypothermia (DH; <22°C) with moderate hypothermia (MH; 22–30°C) during pediatric cardiac surgery.
Does a clinical assessment of upper airway obstruction in robin sequence correspond to sleep study results?
This randomized controlled trial assessed the correlation between clinical evaluations of obstructive sleep apnea (OSA) severity and sleep study results in 29 infants with Robin sequence.
Neurological effects of encapsulated dexamethasone sodium phosphate in children aged 6-9 years with ataxia telangiectasia (NEAT): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
The NEAT trial was a multicentre, randomised, double-blind, placebo-controlled phase 3 study assessing the efficacy and safety of encapsulated dexamethasone sodium phosphate (eDSP) in children aged 6-9 years with ataxia…
Shared Decision-Making and the Role of Maternalism in Resolving Difficult End-of-Life Decisions.
We explore the spectrum of shared decision-making, especially the idea of maternalism, which combines patient or surrogate preferences and goals with the clinician's responsibility to provide care within the boundaries…
Molecular stability overrides size in giant pediatric pheochromocytoma.
A 16-year-old female presented with severe hypertension and hyperglycemia, initially misdiagnosed with essential hypertension and type 2 diabetes.
Biallelic SLC20A2 loss-of-function in severe early-onset neurodevelopmental disorder with brain calcification.
A child presented in early infancy with refractory seizures, severe hypotonia, left hemiplegia, profound developmental impairment, bilateral cataracts, and progressive intracranial calcification.
Long-Term Effects of Kangaroo Mother Care on Neuromotor Development in Adults Born Preterm: A Transcranial Magnetic Stimulation Study.
This cohort analysis followed 214 young adults born weighing ≤ 1800 g who had originally participated in a randomized trial of Kangaroo Mother Care (KMC) versus conventional neonatal care.
Neonatal Hyperthyroidism: Case Report and Literature Review.
A late preterm infant presented with thyrotoxicosis due to maternal Graves disease, which had been treated with radioactive iodine.
Can fluoxetine's diminished efficacy in pediatric depression be explained by study sites, baseline severity, age, and psychological interventions? A secondary exploratory meta-regression.
This meta-analysis explored factors potentially explaining the declining efficacy of fluoxetine in pediatric depression, focusing on study site number, age, baseline severity, and psychological interventions.
Factors influencing shared decision-making in microtia reconstruction: A systematic review.
This systematic review examined factors influencing shared decision-making (SDM) in pediatric microtia reconstruction, analyzing 235 participants including patients, caregivers, and healthcare providers.
Expanding the clinical and molecular spectrum of SETD5, NEDD4L, and TBL1X related disorders: A case report and literature review.
A male child presented with a complex phenotype including intellectual disability, seizures, periventricular nodular heterotopia (PVNH), congenital central hypothyroidism, and multiorgan malformations.
Efficacy and safety of drinking ice-carbonated water and ice-purified water immediately after extubation in paediatric patients with congenital heart disease: A randomised, controlled three-arm trial.
This randomized controlled trial evaluated the efficacy and safety of ice-carbonated water and ice-purified water in alleviating thirst in 108 children aged 3-12 years post-congenital heart disease surgery.
Disseminated Ganciclovir-Resistant Cytomegalovirus in a Nontransplant Pediatric ALL Patient: A Case Report.
An 8-year-old patient with T-ALL on maintenance chemotherapy developed significant CMV viremia without initial end-organ disease, which progressed to ganciclovir-resistant CMV infection.
Experiences and satisfaction with intensive community care services for children and adolescents with severe mental health disorders: a mixed-methods systematic review.
This mixed-methods systematic review examined experiences and satisfaction with intensive community care services (ICCS), alternatives to inpatient care, among children and adolescents under 18 with severe mental health…
Does Timing Matter? A Clinical Trial of Supporting Play Exploration and Early Development Intervention for Infants Born Preterm in the First Months of Life.
This multisite, three-arm randomized controlled trial evaluated whether the timing of a caregiver-supported, motor-based intervention affected development in 83 infants born very preterm (mean gestational age 26.5 ± 2.0…
Seroefficacy of a 10-valent pneumococcal conjugate vaccine (Pneumosil®) compared with other pneumococcal conjugate vaccines in children.
This randomized controlled trial evaluated the seroefficacy of the 10-valent pneumococcal conjugate vaccine (PCV10 SII) in 716 infants compared to PCV10 GSK and PCV13.
EEG-Guided Sevoflurane Anesthesia and Emergence Delirium in Children: A Randomized Controlled Trial.
This randomized controlled trial evaluated EEG-guided anesthesia using SedLine in 100 children aged 4-10 undergoing dental procedures.
Pre-Extubation Low-Dose Propofol in Pediatric Ear, Nose, and Throat Procedures: A Meta-Analysis With Trial Sequential Analysis.
This meta-analysis evaluated the effects of low-dose propofol before extubation in pediatric patients undergoing ENT procedures. It included ten randomized controlled trials with 414 patients.
Metabolic mimic of inherited bone marrow failure: LMBRD1 (cblF) deficiency in an infant.
An eight-month-old boy presented with macrocytic anemia, reticulocytopenia, neutropenia, infections, failure to thrive, and developmental delay.
Interventions to improve vaccination coverage among children aged 12-23 months in urban slum areas of Asia: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed interventions to improve vaccination coverage among children aged 12–23 months in Asian slum areas.
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