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2000 articles
September 202624
Five-year outcomes of partial breast proton beam therapy without lumpectomy for early-stage breast cancer: an interventional prospective study.
This prospective interventional clinical trial evaluated partial breast proton beam therapy (PB-PBT) without tumor resection in women aged 40–70 years with low-risk, early-stage, estrogen receptor-positive…
Transoral robotic reconstruction of a posterior palatal defect using an upper arm flap following polymorphous adenocarcinoma resection: a novel minimally invasive approach.
A 36-year-old female presented with a 1 × 1 cm swelling on the palate, diagnosed as a polymorphous adenocarcinoma after resection.
Disseminated Fusarium infection following cladribine chemotherapy for hairy-cell leukaemia.
A young, healthy patient developed an angioinvasive Fusarium infection following cladribine chemotherapy for hairy cell leukaemia.
Bladder Large Cell Neuroendocrine Carcinoma(LCNEC): A Case Report of Exfoliated Cytology and Pathological Characteristics.
A 77-year-old man presented with recurrent gross hematuria, urinary frequency, urgency, and lumbosacral pain. Imaging revealed a large soft-tissue mass on the bladder wall.
Effect of esketamine on postoperative pulmonary complications after radical surgery for lung cancer: A randomized double-blind controlled trial.
This randomized controlled trial evaluated the effect of perioperative esketamine on postoperative pulmonary complications (PPCs) in 80 patients undergoing thoracoscopic radical lung cancer surgery.
Durable disease control following multidisciplinary treatment including pembrolizumab in POLE-mutated dedifferentiated endometrial carcinoma with brain metastases: A case report.
A 58-year-old woman with POLE-mutated dedifferentiated endometrial carcinoma presented with headache, dizziness, and weakness due to multiple brain and pulmonary metastases.
Risk factors for frailty in older adults with cancer: a systematic review.
This systematic review examined risk factors for frailty in older adults with cancer, integrating data from 30 studies. It identified six categories of influencing factors: disease-related, physiological, psychological…
Cervical Chondrosarcoma: Management Strategies, Technical Considerations, and Long-Term Outcomes.
This article reviews management of cervical spine chondrosarcoma and presents two illustrative cases with long-term follow-up.
Safety and Efficacy of Thermal Ablation for Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma: A Systematic Review of Available Evidence.
This systematic review evaluated the safety and efficacy of thermal ablation techniques (laser ablation, radiofrequency ablation, and microwave ablation) for cervical lymph node metastasis from papillary thyroid…
Safety and efficacy of sonodynamic therapy combined with Stupp regimen in controlling postoperative residual lesions of glioblastoma: A prospective pilot phase I study.
This prospective Phase I trial evaluated the safety and preliminary efficacy of sonodynamic therapy (SDT) combined with the Stupp regimen in 18 newly diagnosed glioblastoma patients with postoperative residual lesions.
Nasal NUT carcinoma with repeated responses during multimodal treatment incorporating radiotherapy: A case report.
A 40-year-old woman with nasal NUT carcinoma presented with severe symptoms including orbital pain, visual impairment, and lower-limb paralysis after initial surgery. Pathologic evaluation confirmed the diagnosis.
Primary breast diffuse large B-cell lymphoma mimicking breast carcinoma: A case report and literature review.
A 59-year-old postmenopausal woman presented with a painless right breast mass, initially suspected to be breast carcinoma based on imaging studies.
Comparative efficacy of traditional Chinese medicine-based non-pharmacological therapies for managing cancer-related fatigue in lung cancer patients: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the efficacy of Traditional Chinese Medicine (TCM)-based non-pharmacological therapies for managing cancer-related fatigue (CRF) in lung cancer patients.
Primary laryngeal paraganglioma with multisystem metastases: A case report.
A patient with laryngeal paraganglioma presented with progressive dysphagia, hoarseness, and dyspnea. Imaging revealed a laryngeal mass, confirmed by histopathology.
Impact of 4D-CT MIP reconstruction method on iGTV definition: A clinical case report.
A case during thoracic radiation therapy planning revealed a discrepancy in tumor extent due to the use of a phase-sorted 4D-CT maximum intensity projection (MIP) dataset, which truncated the inferior tumor boundary.
First-line ibrutinib plus venetoclax for nonblastoid mantle cell lymphoma in patients ≥65 years old or with TP53 mutations.
The phase 3 SYMPATICO study evaluated the efficacy of first-line ibrutinib plus venetoclax in 78 patients with nonblastoid mantle cell lymphoma, specifically those aged ≥65 years or with TP53 mutations.
How I treat chemotherapy-induced thrombocytopenia with thrombopoietin receptor agonists.
The article discusses four cases of chemotherapy-induced thrombocytopenia (CIT), highlighting the complexities of managing this condition.
Fine-Tuning, Retrieval-Augmented Generation, and Hybrid Adaptation of Language Models for Clinical Decision-Making in Health Care: Systematic Review.
This systematic review evaluated the effectiveness of fine-tuning, retrieval-augmented generation (RAG), and hybrid adaptation strategies for transformer-based language models in clinical decision-making.
Dynamic genetic and nongenetic RAS-pathway activation drives resistance to FLT3 and BCL2 inhibitor therapy.
This phase 1b clinical trial investigated the mechanisms of resistance to the BCL2 inhibitor venetoclax and the FLT3 inhibitor gilteritinib in patients with acute myeloid leukemia (AML).
Three-Year Follow-up of the Randomized Trial Comparing Open Versus Laparoscopic Surgery for Primary Tumor Resection in Patients With Noncurable Stage IV Colon Cancer (JCOG1107).
The JCOG1107 trial was a multicenter, open-label, randomized controlled phase III study comparing laparoscopic and open surgery for noncurable stage IV colon cancer.
Evolving idiopathic multicentric Castleman disease with thrombocytopenia, anasarca, fever/hyperinflammation, renal dysfunction and organomegaly presenting with severe hypoalbuminaemia, serositis and bicytopenia before lymphadenopathy.
A man in his early 60s presented with abdominal symptoms, severe hypoalbuminaemia, thrombocytopenia, and marked inflammation, without evident lymphadenopathy.
Orbital lymphoma presenting as preseptal cellulitis in a child with ataxia-telangiectasia.
A young child with ataxia-telangiectasia presented with left periorbital swelling, initially treated as a periorbital infection.
Blinatumomab for Replacing Chemotherapy in Pediatric Acute Lymphoblastic Leukemia.
This Phase III randomized controlled trial evaluated the efficacy of blinatumomab compared to traditional chemotherapy in children with newly diagnosed high-risk B-cell acute lymphoblastic leukemia (ALL).
Effects of self-acupressure on the fatigue-sleep disturbance-depression symptom cluster in breast cancer survivors: a phase III randomised controlled trial.
This phase III randomized controlled trial evaluated the effects of self-acupressure on the fatigue-sleep disturbance-depression symptom cluster (FSDSC) in breast cancer survivors.
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