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1357 articles
October 202624
Comparison of sterile silicone studs and scalp infiltration with lignocaine for the attenuation of the hemodynamic and stress response to skull pin insertion during craniotomy in pediatric neurosurgical patients: a randomized controlled trial : Sterile silicone studs versus lignocaine infiltration for skull pin insertion.
This randomized controlled trial compared sterile silicone studs (SSS) with lignocaine infiltration for skull pin insertion in 64 children aged 12 years or younger undergoing neurosurgery.
Subgroup Analysis of Pooled Phase 3 Efficacy Data From Two Randomized Trials of Gepotidacin Versus Nitrofurantoin in Uncomplicated Urinary Tract Infections (EAGLE-2 and EAGLE-3) Including Participants With Uropathogens Not-Susceptible to Nitrofurantoin.
This pooled subgroup analysis of two phase 3 randomized trials compared gepotidacin with nitrofurantoin in female participants aged ≥12 years with uncomplicated urinary tract infections.
Efficacy and safety of intralesional versus intracoronary administration of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention for acute coronary syndromes: a meta-analysis of randomized controlled trials.
This meta-analysis of nine randomized controlled trials compared intralesional with intracoronary glycoprotein IIb/IIIa inhibitor administration during PCI in patients with acute coronary syndromes.
A Bayesian Re-analysis of the GALFLU Trial of High-Dose vs Standard-Dose Influenza Vaccine Against Hospitalization Outcomes.
This Bayesian re-analysis examined hospitalization outcomes in the GALFLU randomized trial, which compared high-dose with standard-dose inactivated influenza vaccine in adults aged 65–79 years.
Germline BRCA-Lynch syndrome MINAS: report of six Argentinian families and a systematic review of the literature.
This report combined six Argentinian families with a systematic review of 40 publications to describe the phenotype of BRCA-Lynch syndrome (BRCA-LS) MINAS. The analysis included 92 patients from 69 families.
Vascular health after quitting smoking or switching to e-cigarette use: a systematic review of prospective studies with GRADE assessment.
This systematic review assessed prospective evidence on vascular function after smoking cessation or switching to exclusive e-cigarette use among adult smokers.
Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study.
This analysis of HELIOS-B, a double-blind, randomized, placebo-controlled trial, examined individual health-status components in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).
Mitral regurgitation in patients with heart failure and reduced ejection fraction: insights from GALACTIC-HF.
This analysis of the randomized, multicentre GALACTIC-HF trial examined mitral regurgitation (MR) and outcomes in patients with heart failure and reduced ejection fraction.
Can Photobiomodulation improve healing of category II-III pressure ulcers in frail older adults? A quasi-experimental 24-month follow-up study.
This quasi-experimental study compared adjunctive photobiomodulation with standard care for category II and III pressure ulcers in frail adults aged 70 years or older receiving municipal home healthcare.
Assessing stigma and perceptions of respectful care in Malawi's index case testing program: Findings from a cluster randomized controlled trial.
This cluster randomized controlled trial assessed whether enhanced stigma-reduction training improved healthcare worker (HCW) attitudes and client experiences in Malawi’s HIV index case testing program.
Long-term gynecological symptoms and ultrasound and reproductive outcomes after monofilament vs multifilament uterine closure at Cesarean delivery: secondary analysis of randomized controlled trial.
This secondary analysis of a randomized controlled trial compared long-term outcomes after monofilament versus multifilament absorbable uterine closure at Cesarean delivery.
Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing.
This randomized controlled trial tested whether personalizing cognitive remediation (CR) by baseline early auditory processing (EAP) status improved outcomes in 184 outpatient adults with schizophrenia.
An mHealth Stress Management Intervention for Latino Millennial Caregivers: Pilot Feasibility Randomized Controlled Trial.
This pilot feasibility randomized controlled trial evaluated a culturally tailored, automated mobile intervention for stress management and emotional regulation among Latino millennial caregivers in the United States.
Effect of Adding Esketamine to Patient-Controlled Intravenous Analgesia on Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial.
This randomized controlled trial evaluated whether adding esketamine to postoperative patient-controlled intravenous analgesia (PCIA) reduces rebound pain after interscalene brachial plexus block in patients undergoing…
Next-Generation Bed Nets to Control Malaria in Côte d'Ivoire.
This cluster-randomized clinical trial compared pyrethroid-only long-lasting insecticidal nets with piperonyl butoxide-pyrethroid (PBO-py) and chlorfenapyr-pyrethroid (CFP-py) nets in villages in Côte d'Ivoire.
E-Cigarettes with and without Behavioral Support for Smoking Cessation.
This randomized controlled trial compared an e-cigarette starter pack alone, the starter pack plus multisession telephone-based behavioral support, and automated supportive messages among people who smoked and were…
Hippocampal subfield functional connectivity alterations in major depressive disorder: A systematic review and meta-analysis.
This systematic review and meta-analysis examined functional connectivity (FC) involving hippocampal subfields or subregions in major depressive disorder (MDD), comparing findings with healthy controls and summarizing…
Measurement properties of anhedonia-related patient-reported outcome measures in depression-related populations: A COSMIN systematic review.
This COSMIN systematic review evaluated the measurement properties of anhedonia-related patient-reported outcome measures in depression-related populations.
Measuring the impact of migraine: a systematic review of the measurement properties of MIDAS, HIT-6, and MSQoL.
This systematic review compared the measurement properties of MIDAS, HIT-6, and MSQoL for assessing migraine impact. Following COSMIN methods, it included 22 studies with 20,455 participants.
Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.
This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…
Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial.
The multicenter, unblinded pragmatic randomized PRESSURE trial compared a permissive mean arterial pressure (MAP) target (greater than the fifth percentile for age) with usual physician-set targets in hypotensive…
Efficacy and safety of icotrokinra for plaque psoriasis: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed icotrokinra, an oral IL-23 receptor antagonist, in adolescents and adults with moderate-to-severe plaque psoriasis.
The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.
This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.
Effects of Whey Protein Supplementation on Muscle Damage, Hepatic Stress, and Inflammatory Markers in Power- and Endurance-Trained Athletes.
This randomized, double-blind, placebo-controlled trial examined 8 weeks of whey protein supplementation (30 g/day) in 59 male power- and endurance-trained athletes.
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