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2000 articles
September 202624
API-CAT investigators' decisions on anticoagulation following extended treatment for cancer-associated thrombosis.
The API-CAT trial showed that reduced-dose apixaban was noninferior to full-dose for preventing recurrent venous thromboembolism in cancer patients.
Asynchronous bilateral pulmonary pathology: left-sided congenital pulmonary airway malformation with contralateral malignant pleuropulmonary blastoma in an adolescent.
An adolescent boy with a history of left-sided congenital pulmonary airway malformation (CPAM) presented with dry cough, right-sided chest pain, and breathlessness.
Systemic light chain amyloidosis presenting as jejunal perforation.
A patient with recurrent uterine cancer presented with jejunal perforation, a rare complication of systemic light chain amyloidosis.
Phase 1 study of KHK2455, a long-acting, potent and selective IDO1 inhibitor, in combination with avelumab in patients with locally advanced or metastatic urothelial carcinoma.
This Phase 1 multicenter study assessed the safety and preliminary efficacy of KHK2455, an IDO1 inhibitor, combined with avelumab in adults with locally advanced or metastatic urothelial carcinoma.
Modified single-stapled anastomosis in laparoscopic or robotic low anterior resection for rectal cancer: protocol for a multicentre randomised controlled trial.
This multicentre, parallel-group, superiority randomised controlled trial investigates the modified single-stapled technique (MST) versus the conventional double-stapled technique (DST) in 450 patients undergoing…
Male breast cancer in Arab populations: a systematic review of molecular, genetic, and clinicopathologic characteristics.
This systematic review analyzed 54 studies involving 1,534 male breast cancer (MBC) patients from Arab countries, revealing that invasive ductal carcinoma is the most common subtype (92.6%).
Induction and concurrent aumolertinib with radiotherapy for EGFR-mutated stage III NSCLC: results of phase III ADVANCE trial and real-world validation.
The phase III ADVANCE trial evaluated a chemotherapy-free regimen of aumolertinib combined with radiotherapy in patients with unresectable stage III EGFR-mutated non-small cell lung cancer.
Optimising exercise prescription for cancer-related fatigue, lean mass, physical function and muscle strength in women with breast cancer: a systematic review with dose-response network meta-analysis.
This systematic review and dose-response network meta-analysis evaluated the effects of aerobic, resistance, and combined exercise on cancer-related fatigue, lean mass, physical function, and muscle strength in women…
Psychosocial interventions for children and adolescents across the cancer care continuum: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated psychosocial interventions for children and adolescents (0-19 years) with cancer, analyzing their effects on neurocognitive, psychological, and health-related quality…
Pathological complete necrosis after pulmonary thermal ablation: a systematic review and meta-analysis of ablate-and-resect studies.
This systematic review and meta-analysis examined pathological complete tumor necrosis after pulmonary thermal ablation, using eight ablate-and-resect studies comprising 95 evaluable lesions.
Association between hair cortisol concentration and cancer-related outcomes in adult patients: A systematic review.
This systematic review assessed whether hair cortisol concentration (HCC), a marker of cumulative cortisol exposure, is associated with cancer outcomes in adults with confirmed cancer.
Health-related quality of life with adjuvant immune checkpoint inhibition in renal cell carcinoma: A qualitative study of UK participants in the phase III RAMPART trial.
This qualitative study explored the health-related quality of life (HRQoL) impacts of adjuvant immune checkpoint inhibitors (ICIs) in renal cell carcinoma patients from the RAMPART trial.
Discordant pathologic response to neoadjuvant human epidermal growth factor receptor 2-directed therapy in primary breast tumour and axillary lymph node metastases.
A patient with HER2-positive breast cancer received neoadjuvant chemotherapy and HER2-directed therapy, showing significant histological response in the primary breast tumor.
Financial toxicity among families of children with cancer: a qualitative systematic review and meta-aggregation.
This qualitative systematic review synthesized evidence on financial toxicity experienced by families of children with cancer.
Pre-Spondylectomy Radiofrequency Ablation for Spinal Chordoma: An Illustrative Case and Systematic Review of Clinical Applications and Outcomes.
A patient with an L4 chordoma underwent CT-guided radiofrequency ablation (RFA) followed by vertebroplasty as a pre-spondylectomy adjunct. This approach aimed to reduce tumor burden before a staged en bloc resection.
Extraosseous Ewing sarcoma of the common fibular nerve.
A 64-year-old woman presented with progressive weakness of the left foot, leading to the diagnosis of an intraneural extraosseous Ewing sarcoma of the common fibular nerve.
Biomarker Detection of Lung Cancers Before Clinical Symptoms or the Use of Traditional Imaging Methods in the ITALUNG Trial.
The ITALUNG trial, a randomized controlled trial, assessed the efficacy of Low-Dose Computed Tomography (LDCT) for lung cancer screening in over 3100 high-risk individuals aged 55-69.
Stroke secondary to cancer-associated coagulopathy: a systematic review.
This systematic review examined cancer-associated coagulopathy (CAC) as a cause of ischemic stroke in cancer patients, analyzing 82 studies.
A systematic review of cancer risks associated with MITF variants.
This systematic review and meta-analysis evaluated cancer risks associated with germline MITF variants, focusing on 11 retrospective case-control studies involving 8,606 melanoma patients and 17,953 controls.
Acute myeloid leukemia arising in treated chronic lymphocytic leukemia/small lymphocytic lymphoma: a challenge in analysis of lineage relationship.
A 75-year-old female with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma, previously treated with obinutuzumab and venetoclax, presented with acute myeloid leukemia characterized by…
Integration of early palliative care in cancer treatment: a meta-analysis of 39 randomized controlled trials on clinical outcomes and management optimization.
This meta-analysis of 39 randomized controlled trials involving 8399 cancer patients evaluated the impact of early palliative care (EPC) on quality of life (QoL) and survival outcomes.
Prognostic impact of diabetes or hypertension in smokers with CRPC receiving enzalutamide or abiraterone.
This retrospective analysis of the multicentre, randomised ENABLE study examined whether smoking, diabetes mellitus (DM), or hypertension (HT) were associated with survival in patients with castration-resistant prostate…
Tarlatamab in small cell lung cancer following platinum-based chemotherapy: subgroup analysis of Japanese patients from the DeLLphi-304 study.
This randomized Phase III subgroup analysis evaluated tarlatamab versus amrubicin in Japanese patients with small-cell lung cancer progressing after platinum-based chemotherapy.
The Role of the Antidepressants in Managing Chemotherapy-Induced Neuropathic Pain: A Systematic Review.
This systematic review assessed the efficacy and safety of antidepressants, particularly duloxetine and amitriptyline, in managing chemotherapy-induced peripheral neuropathy (CIPN) pain in adults.
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