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1382 articles
August 202624
Giardia duodenalis Infection and Pachymeningitis in a Patient With Agammaglobulinemia.
A 14-year-old patient with X-linked agammaglobulinemia presented with persistent fever, bloody diarrhea, and headache. Chronic giardiasis was identified, and brain MRI showed minimal diffuse dural thickening interpreted…
Safety of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in USA and Puerto Rico: Results from a Phase III, randomized, active-controlled study.
This Phase III randomized controlled trial evaluated the safety of the quadrivalent meningococcal conjugate vaccine MenACYW-TT in healthy infants and toddlers in the USA and Puerto Rico.
Comparison of immunogenicity, safety, and efficacy of EVA71 vaccine in children: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the immunogenicity, safety, and efficacy of inactivated EV-A71 vaccines in children, analyzing data from five phase III RCTs involving 36,659 participants.
A 6-Month-Old Infant with Episodes of Unresponsiveness.
A 6-month-old male infant presented with episodes of unresponsiveness and bluish discoloration of the lips. Through a thorough clinical evaluation, including history-taking and physical examination, a differential…
Intracapsular tonsillectomy/tonsillotomy for severe pediatric obstructive sleep apnea A PRISMA-based systematic review and exploratory meta-analytic synthesis of full-text articles.
This systematic review and meta-analysis evaluated the effectiveness and safety of intracapsular tonsillectomy/tonsillotomy combined with adenoidectomy in children with severe obstructive sleep apnea (OSA).
Short Pancreas in Children With Fanconi Anemia: A Report of Three Cases.
Three children with Fanconi anemia presented with a short pancreas, characterized by the absence of the pancreatic tail, identified through computed tomography.
Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases.
This case series discusses two pediatric patients with medication-resistant epilepsy who underwent ketogenic diet therapy (KDT) while managing ileostomies.
Catheter Ablation for Supraventricular Tachycardia in Infants: A Systematic Review and Selective Meta-Analysis.
This systematic review and selective meta-analysis assessed catheter ablation outcomes for supraventricular tachycardia in infants aged 12 months or younger, generally considered for drug-refractory or life-threatening…
Effects of Immediate Skin-to-Skin Contact in Preterm Infants in High-Resource Settings: A Systematic Review.
This systematic review assessed immediate or early skin-to-skin contact (initiated within 1 hour after birth) versus conventional care for inborn preterm infants in high-resource settings.
Ultrasound-Based Assessment of Gastric Fluid Volume in the Pediatric Population Undergoing Elective Surgery: A Prospective, Randomized, Double-Blind Comparison of Carbohydrate-Rich Clear Fluid Versus Water at One- and Two-Hour Fasting Intervals.
This prospective, randomized, double-blind trial compared gastric fluid volume (GFV) after 3 mL/kg of 10% glucose solution or water, followed by a one- or two-hour fast, in 140 healthy children aged 1–12 years…
Cost-Effectiveness of a Child and Parent Mindfulness-Based Training Versus Medication for Childhood ADHD.
This randomized controlled trial evaluated the cost-effectiveness of family mindfulness training ('MYmind') compared to medication for childhood ADHD in 88 children.
Single-stage surgical management versus conventional two-stage management for pediatric choledocholithiasis: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared single-stage with conventional two-stage management of choledocholithiasis in children. Eight retrospective cohort studies included 562 patients.
Systematic review of the mutations in the active antigenic site Ø of the prefusion F protein of the Respiratory Syncytial Virus (RSV) following the implementation of monoclonal antibody prophylaxis.
This systematic review analyzed mutations in the antigenic site Ø of the RSV prefusion F protein following the introduction of the monoclonal antibody nirsevimab in children with confirmed RSV infections.
Caregiver-reported short-term effect and quality of life improvements after tympanostomy tube insertion in children with chronic otitis media with effusion.
This randomized controlled trial evaluated caregiver-reported outcomes following tympanostomy tube insertion (TTI) in 60 children aged 1-4 years with chronic otitis media with effusion.
Chloral hydrate outperforms oral midazolam in facilitating venipuncture in children: A double-blind randomized trial.
This prospective, double-blind randomized trial compared oral chloral hydrate with oral midazolam for facilitating venipuncture in hospitalized children aged 1–5 years in a tertiary hospital emergency department.
Neurocognitive deficits in children with polysomnographically confirmed obstructive sleep apnea: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated neurocognitive deficits in school-aged children (mean age 5-12 years) with polysomnographically confirmed obstructive sleep apnea (OSA).
Socioeconomic determinants of recurrent DKA in US children.
This systematic review examined U.S. observational studies linking socioeconomic factors with recurrent diabetic ketoacidosis (DKA) in children.
Targeting coping strategies, emotion regulation, and self-esteem in children with dyslexia to support mental health: A randomized-controlled trial of Clever Kids.
This pre-registered randomized controlled trial evaluated Clever Kids, a nine-week socio-emotional programme, in 78 children with clinically diagnosed dyslexia (mean age 10.19 years; 54% female).
Pathways of onward HIV disclosure in relationships among young people living with vertically acquired HIV receiving antiretroviral therapy: A qualitative analysis from the BREATHER Plus trial, South Africa.
This qualitative analysis from the BREATHER Plus trial explored how young people living with vertically acquired HIV in KwaZulu-Natal, South Africa, manage onward disclosure in relationships.
Umbilical Cord-Derived Cell-Based Interventions for Bronchopulmonary Dysplasia and Related Complications in Preterm Infants: A Bayesian Sparse-Data Meta-Analysis.
This meta-analysis evaluated umbilical cord-derived cell-based interventions for bronchopulmonary dysplasia (BPD) in preterm infants.
Exploring the Feasibility of Ultrasound-Guided Supraclavicular Nerve Blocks for Distal Forearm Fracture Management in Pediatric Patients.
Three pediatric patients presented with distal forearm fractures requiring reduction. Due to various factors, including the need to monitor the Glasgow coma scale and parental preferences, ultrasound-guided…
Minor physical anomalies in ASD and ADHD: a systematic review and meta-analysis.
This systematic review and meta-analysis examined minor physical anomalies (MPAs) in individuals with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) compared to typically developing…
Functional Outcomes of Pediatrics and Adolescent Pelvic Fractures: A Systematic Review.
This Level III systematic review assessed functional and structural outcomes after pelvic fractures in children and adolescents, drawing on 14 retrospective and prospective cohort studies and case series (n=731).
Autism and Self-Esteem: A Systematic Review Quantifying Differences Between Autistic and Non-Autistic Adolescents and Investigating Associations With Mental Health Difficulties.
This systematic review examined self-esteem in autistic adolescents aged 10–19 years, comparing levels with non-autistic peers and assessing associations with mental health symptoms.
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