Trending archive
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1382 articles
September 20263
Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.
We describe biochemically and functionally validated primary bile acid malabsorption caused by novel biallelic SLC10A2 variants in a child initially diagnosed with Crohn's disease.
ALA-PDT for giant condyloma acuminatum in an immunodeficient child with BCL11B mutation: safety and efficacy.
A pair of siblings with a BCL11B mutation presented with giant condyloma acuminatum and intellectual developmental disorder.
Variants in the Imprinted IGF2 Gene: A Review and Phasing of De Novo Variants Using Long-Read Sequencing.
Two unrelated individuals, a 5-year-old girl and an adult woman, were diagnosed with Silver-Russell syndrome (SRS) and found to have de novo missense variants in IGF2.
August 202621
Pregnancy diet based on ancestral patterns increases growth in subcortical fetal brain regions.
This randomized controlled trial in Ecuador examined the impact of a maternal diet based on ancestral patterns on fetal brain development.
The effect of BIS-guided sevoflurane anesthesia on postoperative nausea and vomiting in pediatric adenoidectomy: a prospective randomized controlled trial.
This prospective randomized controlled trial evaluated the impact of BIS-guided sevoflurane anesthesia on postoperative nausea and vomiting (PONV) in 58 children aged 3-8 undergoing adenoidectomy.
Honey vs. pharmacological treatment for acute cough in children: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effectiveness of honey compared to pharmacological treatments for acute cough in children, analyzing data from 7 studies involving 576 patients.
Interventions for primary pediatric tracheomalacia: A systematic review of the therapeutic landscape and evidence quality.
This systematic review evaluated interventions for primary pediatric tracheomalacia, analyzing 22 studies involving 764 participants.
Paediatric Hand Compartment Syndrome Secondary to Intravenous Contrast Extravasation: A Case Report.
A 9-year-old girl developed hand compartment syndrome after 50 mL of iohexol extravasation during a contrast-enhanced abdominal CT.
Treatment Approaches for Pre-Eruptive Intracoronal Resorption According to Lesion Grade and Pulp Involvement: A Systematic Review of Case Reports and Case Series.
This systematic review synthesized case reports and case series describing treatment of pre-eruptive intracoronal resorption (PEIR), a condition without standardized treatment guidelines.
The NU-HOME RCT home food environment, family meal frequency, meal quality and children's dietary intake and physical activity outcomes.
This randomized controlled trial evaluated secondary outcomes of the NU-HOME family-based obesity-prevention program in 114 rural children aged 7–10 years.
An Individualized Approach to Augmentative and Alternative Communication for Cortical Visual Impairment: One Family's Progression Toward an Accessible Language System.
A young child with cerebral palsy and concomitant cortical visual impairment (CVI) needed an augmentative and alternative communication (AAC) system that accommodated visual and motor support needs.
Behavioral interventions for sleep problems in autistic children: A systematic review.
This systematic review evaluated the effectiveness of behavioral sleep interventions for sleep problems in autistic children under 18 years.
Long-term outcome after fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia: systematic review.
This systematic review assessed long-term outcomes after fetal endoscopic tracheal occlusion (FETO) for congenital diaphragmatic hernia (CDH).
The Impact of Mindfulness as a Session-Introduction on Symptoms and Alliance in Individual Cognitive-Behavioral Therapy With Children and Adolescents: A Randomized Controlled Trial.
This randomized controlled trial examined whether beginning individual cognitive-behavioral therapy sessions with mindfulness improved symptoms or therapeutic alliance among 90 outpatient adolescents aged 11–19 years…
Autologous cricoid graft reconstruction of complete transglottic laryngeal atresia: Case report.
A male infant with congenital high airway obstruction syndrome underwent EXIT-to-tracheostomy at 32 weeks. At three years, he was found to have complete transglottic laryngeal atresia with severe cricoid dysplasia.
HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities.
HOPE Kids 2 was a phase 3, multicenter, double-blind, placebo-controlled randomized trial of voxelotor in children aged 2 to <15 years with sickle cell disease (HbSS/HbSβ⁰) and conditional cerebral blood flow velocities…
Recurrent Sterile Polyserositis Reveals an Underrecognized Autoinflammatory Phenotype in MECP2 Duplication Syndrome.
In a retrospective multicenter review of four patients with MECP2 duplication syndrome, each developed recurrent pleural and/or pericardial effusions with systemic inflammation, including leukocytosis, elevated…
Changes in Composite Cardiovascular Risk Scores from Childhood to Adulthood and Cardiometabolic Outcomes in Adulthood: A Systematic Review.
This systematic review synthesised population-based longitudinal studies examining how composite cardiovascular risk scores change from childhood to adulthood and relate to adult cardiometabolic outcomes.
Child Neurology: Radiologic Evolution and Developmental Correlates in Fetal Cerebral Sinovenous Thrombosis: A Case Report.
This case report discusses two children diagnosed with fetal cerebral sinovenous thrombosis (CSVT) via fetal MRI. Serial neuroimaging revealed significant evolution in cerebrovascular pathology, including changes in…
Dyspnea in Children with Serious Illness.
Dyspnea is a common and distressing symptom in children living with serious illnesses, particularly near the end of life, and requires thoughtful, family-centered assessment and management.
A multi-center, open-labelled, randomized controlled extended phase III non-inferiority clinical trial to evaluate the immunogenicity and tolerability of poliomyelitis vaccine (Vero cells), inactivated, Sabin strains administered with or without routine infant vaccines.
This multi-center, open-label, randomized controlled trial evaluated the immunogenicity and tolerability of inactivated poliomyelitis vaccine (sIPV) administered with or without routine infant vaccines in 1442 healthy…
Long-Term Restoration of Anticoagulant Function After Liver Transplantation for Severe Congenital Protein C Deficiency: A Single-Center Experience Involving Three Pediatric Patients.
Three pediatric patients with severe congenital protein C deficiency underwent liver transplantation, resulting in plasma protein C activity levels exceeding 64% post-surgery.
Malaria Vaccine Rollout in Nigeria: Current Status and Challenges.
This systematic review examined implementation, awareness, acceptance, willingness to pay, and health system readiness for malaria vaccine rollout in Nigeria.
Adjunctive pillar suturing or pharyngoplasty in pediatric adenotonsillectomy for obstructive sleep apnea: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of adjunctive pillar suturing or pharyngoplasty in pediatric adenotonsillectomy for obstructive sleep apnea (OSA).
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