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2000 articles
September 202624
Meaning-centered psychotherapy for existential distress in advanced cancer: A culturally informed case report from Vietnam.
A 24-year-old Vietnamese woman with advanced cancer presented with severe depressive symptoms, emotional instability, and passive wishes for death.
A case report on the management of sepsis complicated by eroded mixed hemorrhoids following breast cancer chemotherapy.
A 51-year-old female with stage IIIA breast cancer developed septicemia and eroded mixed hemorrhoids following chemotherapy. She presented with severe neutropenia and a high fever.
Vision loss as the first manifestation of isolated cns relapse in CML blast crisis during flumatinib maintenance therapy: A case report.
A 65-year-old male with chronic myeloid leukemia in complete remission presented with progressive vision loss, indicating isolated CNS relapse.
Intratumoral and Peritumoral Features for Predicting Microvascular Invasion in Hepatocellular Carcinoma: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the effectiveness of radiomics-based models in predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC).
Sarcopenia Is Associated With Severe Treatment Toxicity and Mortality in Older Adults With Advanced Cancer: A Secondary Analysis.
This secondary analysis of a randomized controlled trial examined the impact of sarcopenia on treatment outcomes in 161 older adults (≥ 70 years) with advanced cancer.
Electronic patient-reported outcome platforms used in hematological cancers: a systematic review.
This systematic review examined electronic patient-reported outcome measures (ePROMs) in hematological cancers, identifying 14 platforms from 18 studies.
Fasting-induced metabolic reprogramming as a therapeutic vulnerability in cancer: a systematic mechanistic review of in vitro evidence.
This systematic review evaluated in vitro studies on fasting and fasting-mimicking interventions in cancer cell models. It found that fasting consistently reduced IGF-1 signaling and inhibited key metabolic pathways…
Fourteen-Year Course of Multiple Recurrent and Distantly Metastatic Hepatic Epithelioid Hemangioendothelioma With Serial Ki-67 Evolution: A Case Report.
A 48-year-old woman with hepatic epithelioid hemangioendothelioma (HEHE) underwent right partial hepatectomy after a liver lesion was found incidentally. Histological analysis confirmed the diagnosis.
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.
Mucinous adenocarcinoma presenting as adult colonic intussusception: A case report.
A 75-year-old woman with multiple comorbidities presented with hematochezia, abdominal distension, intermittent colicky pain, and weight loss.
Iberdomide plus daratumumab and dexamethasone versus daratumumab, bortezomib, and dexamethasone in patients with relapsed or refractory multiple myeloma (EXCALIBER-RRMM): an open-label, randomised, controlled, phase 3 trial.
EXCALIBER-RRMM is an ongoing, open-label, randomised phase 3 trial comparing iberdomide, daratumumab, and dexamethasone with daratumumab, bortezomib, and dexamethasone in adults with relapsed or refractory multiple…
Unusual pelvic mass in a young adult: prostatic Ewing's sarcoma with distant metastases.
A man in his 20s presented with urinary obstruction, constipation, and leg pain. Imaging revealed a bulky pelvic mass from the prostate, leading to bilateral hydroureteronephrosis.
Progression-free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the validity of progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints for overall survival (OS) in randomized controlled trials of…
Lung Adenocarcinoma Presenting as Bilateral Nonresolving Pneumonia Mimicking Pulmonary Infection.
A 63-year-old nonsmoking woman presented with chronic cough, low-grade fever, progressive weight loss, and worsening breathlessness.
Pure Red Cell Aplasia Following Neoadjuvant Docetaxel/Carboplatin/Trastuzumab (TCbH) in a 45‑Year‑Old Woman With Breast Cancer Successfully Treated With Cyclosporine.
A 45-year-old woman with HER2-positive breast cancer developed pure red cell aplasia (PRCA) after neoadjuvant treatment with docetaxel/carboplatin/trastuzumab.
Association Between Metabolic and Bariatric Surgery and Melanoma Risk: A Systematic Review and Meta-analysis of Observational Studies.
This systematic review and meta-analysis of observational studies assessed whether metabolic and bariatric surgery (MBS) was associated with melanoma incidence compared with no MBS.
Evaluating the Impact of CYP1A2 Inhibition on the Pharmacokinetics of Savolitinib: A Phase 1 Open-Label Study.
This Phase 1 open-label study assessed the effects of CYP1A2 inhibition by fluvoxamine on the pharmacokinetics of savolitinib in 16 healthy male volunteers.
Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma.
This phase 1 multicenter study evaluated the safety and efficacy of anitocabtagene autoleucel (anito-cel), a BCMA-directed CAR T-cell therapy, in 40 patients with relapsed or refractory multiple myeloma.
Immune Checkpoint Inhibition in Locally Advanced Periocular Squamous Cell Carcinoma (POLA-SCC).
A 75-year-old man presented with recurrent upper eyelid squamous cell carcinoma (SCC) that persisted despite multiple surgical excisions and reconstructive efforts, leading to significant eyelid dysfunction and visual…
Primary Orbital Melanoma: A Systematic Review of Clinical Characteristics, Management and Outcomes.
This systematic review evaluated clinical characteristics, management, and outcomes of 112 patients with histopathologically confirmed primary orbital melanoma (POM).
Jejunal metastatic melanoma presenting with occult gastrointestinal haemorrhage and refractory anaemia.
An elderly man with a history of cutaneous melanoma presented with chronic iron-deficiency anemia and weight loss. Imaging and endoscopy failed to provide a definitive diagnosis, revealing only an aneurysmal jejunal…
When immunotherapy mimics pancreatic cancer: mass-forming immune-related pancreatitis during neoadjuvant treatment for triple-negative breast cancer.
A woman with early triple-negative breast cancer developed four hypermetabolic pancreatic lesions after 4 months of neoadjuvant chemoimmunotherapy, initially suggestive of metastases.
Classic mantle cell lymphoma with aberrant immunohistochemical expression of Fc receptor-like 4/immunoglobulin superfamily receptor translocation-associated 1.
A patient diagnosed with classic mantle cell lymphoma (MCL) presented with typical clinical, morphologic, immunophenotypic, and genetic features.
Prognostic Value of the C-Reactive Protein-Albumin-Lymphocyte Index in Hepatobiliary and Pancreatic Cancers: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in patients with hepatobiliary and pancreatic cancers.
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