Trending archive
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542 articles
January 202610
Associations of Physical Activity Trajectories With Transitions Across Cognitive States: A Multinational Cohort Study.
This multinational cohort study examined whether physical activity (PA) trajectories were associated with transitions among no cognitive impairment, mild cognitive impairment (MCI), and dementia in data from HRS, ELSA…
Dialysis versus conservative kidney management in older adults: why one size does not fit all.
This narrative review synthesized observational, cohort, and systematic review evidence comparing dialysis with conservative kidney management (CKM) in adults aged ≥70 years with stage 4–5 chronic kidney disease.
Systematic Reviews of Psychosocial Interventions for Loneliness Among Older Adults in Community and Residential Care Settings: An Umbrella Review.
This umbrella review, conducted using Joanna Briggs Institute methodology, examined psychosocial interventions for loneliness among older adults in community and residential care settings.
Barriers and Facilitators for the Adaptation and Implementation of Cognitive Stimulation Therapy: A Systematic Review.
This systematic review examined barriers and facilitators encountered when adapting or implementing Cognitive Stimulation Therapy (CST) across countries.
Prolonged remission of dermatomyositis and autoantibody negativization following SARS-CoV-2 infection in an elderly patient.
An 80-year-old patient with dermatomyositis diagnosed in 2014 had initially responded to methotrexate. After severe SARS-CoV-2 infection with significant pulmonary involvement in March 2022, methotrexate was stopped.
Sustained salivary IgG but short-lived IgA responses following primary and booster MenACWY-TT vaccination in older adults.
This phase IV, open-label clinical trial assessed salivary antibody responses after primary MenACWY-TT vaccination in 216 adults aged 65–85 years; 100 participants received a booster one year later.
Intervention Without Borders - an Automated Self-Guided AI-Enhanced Psychoeducation Intervention for Dementia Caregivers: Parallel-Group Randomized Waitlist-Controlled Trial.
This parallel-group randomized waitlist-controlled trial evaluated PDC30, a fully automated, self-guided online psychoeducation intervention, in 274 caregivers from 43 countries.
Association between anaemia and osteoporosis: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined the association between anaemia and osteoporosis in 18 studies involving 861,540 participants.
Diagnostic and Surgical Challenges of Cauda Equina Syndrome in Elderly Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis of Clinical, Radiological, and Surgical Outcomes.
This systematic review and meta-analysis assessed diagnostic presentation, surgery, complications, and recovery in elderly patients with diabetes and confirmed cauda equina syndrome (CES).
Nurse- and Caregiver-Led Oral Health Interventions in Older Adults Living in LongTerm Care Facilities: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed nurse- or caregiver-led oral health interventions for adults aged 60 years and older in long-term care facilities.
December 202510
Factors Affecting Well-Being and Quality of Life From the Perspective of People With Moderate-To-Severe Dementia: A Qualitative Evidence Synthesis.
This systematic review and qualitative thematic synthesis examined what people with moderate-to-severe dementia consider important for well-being and quality of life.
Efficacy of Brexpiprazole on Neuropsychiatric Symptoms and Impact on Caregivers: Pooled Neuropsychiatric Inventory (NPI) Analysis in Patients With Agitation Associated With Dementia due to Alzheimer's Disease.
This exploratory pooled analysis examined Neuropsychiatric Inventory (NPI) outcomes from two randomized, double-blind, placebo-controlled trials of brexpiprazole for agitation associated with Alzheimer’s disease…
Association of Preoperative Frailty and Postoperative Outcomes in Older Adults Undergoing Major Cardiac Procedures: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined preoperative frailty and postoperative outcomes in older adults undergoing major cardiac procedures.
Evaluation of Non-Pharmacological Interventions for Community-Dwelling Individuals With Dementia Experiencing Sleep Disturbances: An Updated Systematic Review.
This updated systematic review examined randomised controlled trials of non-pharmacological interventions for sleep disturbances in community-dwelling people living with dementia.
The impact of the COVID-19 pandemic on osteoporotic fractures: a systematic review and meta-analysis.
This systematic review and meta-analysis examined observational or retrospective studies comparing osteoporotic fracture incidence in 2020 with 2019. Nine studies were included.
Impact of a physiotherapy-led low threshold exercise and protein supplementation intervention to optimise physical function and target frailty in people experiencing homelessness and addiction: The LEAP-II trial.
The LEAP-II trial was a pre-post intervention study at a day service centre, evaluating a physiotherapy-led, low-threshold exercise programme with protein supplementation among people experiencing homelessness and…
Beyond strength: dietary nitrate augments self-selected functional mobility after resistance training in middle-aged adults.
This 12-week randomized, double-blind, placebo-controlled pilot trial tested whether dietary nitrate added to resistance training improved gait and functional mobility in 28 healthy, inactive adults aged 56 ± 7 years.
Cognitive training effects are shaped more by individual brain dynamics than age-evidence from younger and older women.
This randomized controlled trial examined EEG functional connectivity during task switching in 39 younger women aged 18–25 and 40 older women aged 60–75.
Comparing rehabilitation with and without neuromuscular electrical stimulation in hospitalized older adults: Cognitive, functional, and acceptability outcomes from a pragmatic pilot study.
This pragmatic pilot comparative study examined whether adding neuromuscular electrical stimulation (NMES) to usual rehabilitation affected cognition, mobility, and acceptability among 29 hospitalized older adults (mean…
The Impact of Nutritional Status on Oral Health Outcomes and Management in Older Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between nutritional status and oral health in adults aged 75 years or older.
November 20253
Mental Health Outcomes Associated with Elder Abuse: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined quantitative studies of elder abuse and DSM-5-defined mental health outcomes in adults aged 60 years or older. It included 23 studies and 73 effect sizes.
Impact of Chewing Behavior Change on Cognition and Cerebral Hemodynamics.
This randomized controlled trial tested whether encouraging thorough chewing during meals affects cognition and cerebral hemodynamics in adults aged 65 years or older.
Association of the Timed Up and Go Test With Alzheimer's Disease: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined whether Timed Up and Go (TUG) performance is associated with mild cognitive impairment (MCI) or Alzheimer’s disease (AD) in adults.
October 20251
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